Comprehensive virtual screening of 4.8k flavonoids reveals novel insights into the allosteric inhibition of SARS-CoV-2 M(PRO)

por Paula Vargas Ruiz, Ana, Jiménez Avalos, Gabriel, Delgado, Nicolás E., Olivos Ramírez, Gustavo, Sheen, Patricia, Quiliano, Miguel, Zimic, Mirko
Publicado 2022

Cryo-electron tomography of in vivo reconstituted SARS-CoV-2 replication/transcription organelles

por Buffalo, Cosmo Z., Hurley, James H.
Publicado 2022

Developing lectins as inhibitors of SARS-CoV2

por Guseman, Alex J., Murphy, Linda, Nambulli, Sham, Bhinderwhala, Fatema, Duprex, Paul, Gronenborn, Angela M.
Publicado 2022

Ensemble-based, glycan-dependent epitope analysis of SARS-CoV-2 spike protein

por Chen, Tianle, Kapoor, Karan, Tajkhorshid, Emad
Publicado 2022

Structure function characterization of SARS CoV2 proteases for COVID19 antiviral development

por Greene-Cramer, Rebecca, Bafna, Khushboo, White, Kris, Harish, Balasubramanian, Rosales, Romel, Ramelot, Theresa, Acton, Thomas B., Del Olmo, Elena Moreno, Kehrer, Thomas, Miorin, Lisa, Royer, Catherine A., Garcia-Sastre, Adolfo, Krug, Robert, Montelione, Gaetano T.
Publicado 2022

Expression of SARS-CoV-2-ORF3a protein induces cardiomyocyte damage

por Polina, Iuliia A., Guo, Yugene, Cypress, Michael W., Tolkacheva, Elena G., Sook Jhun, Bong, O-Uchi, Jin
Publicado 2022

Whole-cell quantitative imaging of structural changes induced by SARS-CoV-2 using soft X-ray tomography

por Chen, Jian-Hua, Loconte, Valentina, Cortese, Mirko, Ekman, Axel, Le Gros, Mark A., Bartenschlager, Ralf, Weinhardt, Venera, Larabell, Carolyn A.
Publicado 2022

Machine learning reveals the critical interactions for SARS-CoV-2 spike protein binding to ACE2

por Pavlova, Anna, Zhang, Zijian, Acharya, Atanu, Lynch, Diane L., Tik Pang, Yui, Mou, Zhongyu, Parks, Jerry M., Chipot, Christophe J., Gumbart, James C.
Publicado 2022

Fluorescence correlation spectroscopy measurements of proteins expressed inside microcapsules

por Liu, Chao, Hoang-Phou, Steven A., Ye, Congwang, Laurence, Matthew J., Rubinfeld, Bonnee, Desautels, Thomas A., Smith, Willaim L., Fong, Erika J., Watkins, Nicholas N., Gilmore, Sean F., Shusteff, Maxim, Laurence, Ted A., Coleman, Matthew A.
Publicado 2022

Automated refinement protocol to improve the quality of protein structures deposited in the protein data bank, applied to SARS-Cov-2

por Farrell, Joseph, Haddadian, Esmael J.
Publicado 2022

Decreased interfacial dynamics caused by the N501Y mutation in the SARS-Cov-2 s1 spike:ACE2 complex

por Ahmed, Wesam S., Philip, Angelin M., Biswas, Kabir H.
Publicado 2022

Binding and compaction function of structural domains of SARS-CoV-2 nucleocapsid (N) protein on a single stranded nucleic acid substrate

por Morse, Michael, Sefcikova, Jana, Rouzina, Ioulia, Beuning, Penny J., Williams, Mark C.
Publicado 2022

Impact of SARS-CoV-2 spike protein on α7 nicotinic acetylcholine receptor in cells

por Tillman, Tommy S., Xu, Yan, Tang, Pei
Publicado 2022

Conformational changes in SARS-CoV-2 spike from the delta variant enhances viral transmissibility

por Venkatakrishnan, Varun, Braet, Sean, Buckley, Theresa, Anand, Ganesh S.
Publicado 2022

Predictive mathematical models of the growth of the COVID-19 pandemic

por Luis Fernández-Martínez, Juan, Fernández-Muñiz, Zulima, Cernea, Ana, Kloczkowski, Andrzej
Publicado 2022

Nanoscale membrane curvature facilitate chikungunya viral replication complex assembly via nonstructural protein 1

por Miao, Xinwen, Yien Law, Cheok, Law, Yee-Song, Zeng, Yongpeng, Bia Tan, Yaw, Zhang, Kuo, Zhuang, Yinyin, Wu, Jiawei, Gao, Weibo, Luo, Dahai, Zhao, Wenting
Publicado 2022

Elucidating the distinct structural features of the SARS-CoV-2 spike protein fusion domain

por Birtles, Daniel
Publicado 2022

Intricacies of the SARS-CoV-2 spike transmembrane trimer organization

por Aliper, Elena T., Krylov, Nikolay A., Polyansky, Anton A., Efremov, Roman G.
Publicado 2022

Characterizing the roles of chemo-mechanical couplings in the differential behavior of SARS-CoV-1 and SARS-CoV-2 spike glycoprotein

por Isu, Ugochi H., Govind Kumar, Vivek, Derakhshani-Molayousefi, Mortaza, Polasa, Adithya, Moradi, Mahmoud
Publicado 2022

Direct imaging of RNA loaded lipid-nanoparticles’ self assembly and cellular expression for cancer immunotherapy and RNA-based vaccines

por Ashbrook, Jewel, Chung, Michael C., Mendez-Gomez, Hector, Sayour, Elias, Guan, Juan
Publicado 2022