EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration

por Jayatilaka, Hasini, Giri, Anjil, Karl, Michelle, Aifuwa, Ivie, Trenton, Nicholaus J., Phillip, Jude M., Khatau, Shyam, Wirtz, Denis
Publicado 2018

FGF21 induced by carbon monoxide mediates metabolic homeostasis via the PERK/ATF4 pathway

por Joe, Yeonsoo, Kim, Sena, Kim, Hyo Jeong, Park, Jeongmin, Chen, Yingqing, Park, Hyeok-Jun, Jekal, Seung-Joo, Ryter, Stefan W., Kim, Uh Hyun, Chung, Hun Taeg
Publicado 2018

Reduced SERCA activity underlies dysregulation of Ca(2+) homeostasis under atmospheric O(2) levels

por Keeley, Thomas P., Siow, Richard C. M., Jacob, Ron, Mann, Giovanni E.
Publicado 2018

Hexose-6-phosphate dehydrogenase controls cancer cell proliferation and migration through pleiotropic effects on the unfolded-protein response, calcium homeostasis, and redox balan...

por Tsachaki, Maria, Mladenovic, Natasa, Štambergová, Hana, Birk, Julia, Odermatt, Alex
Publicado 2018

Harnessing an RNA-mediated chaperone for the assembly of influenza hemagglutinin in an immunologically relevant conformation

por Yang, Seung Won, Jang, Yo Han, Kwon, Soon Bin, Lee, Yoon Jae, Chae, Wonil, Byun, Young Ho, Kim, Paul, Park, Chan, Lee, Young Jae, Kim, Choon Kang, Kim, Young Seok, Choi, Seong Il, Seong, Baik Lin
Publicado 2018

Androgens trigger different growth responses in genetically identical human hair follicles in organ culture that reflect their epigenetic diversity in life

por Miranda, Benjamin H., Charlesworth, Matthew R., Tobin, Desmond J., Sharpe, David T., Randall, Valerie A.
Publicado 2018

AMPK in skeletal muscle function and metabolism

por Kjøbsted, Rasmus, Hingst, Janne R., Fentz, Joachim, Foretz, Marc, Sanz, Maria-Nieves, Pehmøller, Christian, Shum, Michael, Marette, André, Mounier, Remi, Treebak, Jonas T., Wojtaszewski, Jørgen F. P., Viollet, Benoit, Lantier, Louise
Publicado 2018

Differential susceptibility of Dectin-1 isoforms to functional inactivation by neutrophil and fungal proteases

por Griffiths, James S., Thompson, Aiysha, Stott, Matthew, Benny, Ankita, Lewis, Natalie A., Taylor, Philip R., Forton, Julian, Herrick, Sarah, Orr, Selinda J., McGreal, Eamon P.
Publicado 2018

Depletion of microglia augments the dopaminergic neurotoxicity of MPTP

por Yang, Xiaoxia, Ren, Honglei, Wood, Kristofer, Li, Minshu, Qiu, Shenfeng, Shi, Fu-Dong, Ma, Cungen, Liu, Qiang
Publicado 2018

Molecular basis for intestinal mucin recognition by galectin-3 and C-type lectins

por Leclaire, Charlotte, Lecointe, Karine, Gunning, Patrick A., Tribolo, Sandra, Kavanaugh, Devon W., Wittmann, Alexandra, Latousakis, Dimitrios, MacKenzie, Donald A., Kawasaki, Norihito, Juge, Nathalie
Publicado 2018

Intraring allostery controls the function and assembly of a hetero-oligomeric class II chaperonin

por Shoemark, Deborah K., Sessions, Richard B., Brancaccio, Andrea, Bigotti, Maria Giulia
Publicado 2018

Analysis of chromatin accessibility in decidualizing human endometrial stromal cells

por Vrljicak, Pavle, Lucas, Emma S., Lansdowne, Lauren, Lucciola, Raffaella, Muter, Joanne, Dyer, Nigel P., Brosens, Jan J., Ott, Sascha
Publicado 2018

Therapeutic exploitation of IPSE, a urogenital parasite-derived host modulatory protein, for chemotherapy-induced hemorrhagic cystitis

por Mbanefo, Evaristus C., Le, Loc, Pennington, Luke F., Odegaard, Justin I., Jardetzky, Theodore S., Alouffi, Abdulaziz, Falcone, Franco H., Hsieh, Michael H.
Publicado 2018

Dynamic structure mediates halophilic adaptation of a DNA polymerase from the deep-sea brines of the Red Sea

por Takahashi, Masateru, Takahashi, Etsuko, Joudeh, Luay I., Marini, Monica, Das, Gobind, Elshenawy, Mohamed M., Akal, Anastassja, Sakashita, Kosuke, Alam, Intikhab, Tehseen, Muhammad, Sobhy, Mohamed A., Stingl, Ulrich, Merzaban, Jasmeen S., Di Fabrizio, Enzo, Hamdan, Samir M.
Publicado 2018

Epicutaneous administration of the pattern recognition receptor agonist polyinosinic–polycytidylic acid activates the MDA5/MAVS pathway in Langerhans cells

por Tajpara, Pooja, Schuster, Christopher, Schön, Elisabeth, Kienzl, Philip, Vierhapper, Martin, Mildner, Michael, Elbe-Bürger, Adelheid
Publicado 2018

Medullary thick ascending limb impairment in the Gla(tm)Tg(CAG-A4GALT) Fabry model mice

por Maruyama, Hiroki, Taguchi, Atsumi, Nishikawa, Yuji, Guili, Chu, Mikame, Mariko, Nameta, Masaaki, Yamaguchi, Yutaka, Ueno, Mitsuhiro, Imai, Naofumi, Ito, Yumi, Nakagawa, Takahiko, Narita, Ichiei, Ishii, Satoshi
Publicado 2018

Differential roles for cryptochromes in the mammalian retinal clock

por Wong, Jovi C. Y., Smyllie, Nicola J., Banks, Gareth T., Pothecary, Carina A., Barnard, Alun R., Maywood, Elizabeth S., Jagannath, Aarti, Hughes, Steven, van der Horst, Gijsbertus T. J., MacLaren, Robert E., Hankins, Mark W., Hastings, Michael H., Nolan, Patrick M., Foster, Russell G., Peirson, Stuart N.
Publicado 2018

Eliciting unnatural immune responses by activating cryptic epitopes in viral antigens

por Lee, Young Jae, Yu, Ji Eun, Kim, Paul, Lee, Jeong-Yoon, Cheong, Yu Cheol, Lee, Yoon Jae, Chang, Jun, Seong, Baik Lin
Publicado 2018

Macrophage-derived extracellular vesicles mediate smooth muscle hyperplasia: role of altered miRNA cargo in response to HIV infection and substance abuse

por Sharma, Himanshu, Chinnappan, Mahendran, Agarwal, Stuti, Dalvi, Pranjali, Gunewardena, Sumedha, O’Brien-Ladner, Amy, Dhillon, Navneet K.
Publicado 2018

Effective control of neuropathic pain by transient expression of hepatocyte growth factor in a mouse chronic constriction injury model

por Nho, Boram, Lee, Junghun, Lee, Junsub, Ko, Kyeong Ryang, Lee, Sung Joong, Kim, Sunyoung
Publicado 2018