Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans

por Movérare-Skrtic, Sofia, Nilsson, Karin H., Henning, Petra, Funck-Brentano, Thomas, Nethander, Maria, Rivadeneira, Fernando, Coletto Nunes, Glaucia, Koskela, Antti, Tuukkanen, Juha, Tuckermann, Jan, Perret, Christine, Souza, Pedro Paulo Chaves, Lerner, Ulf H., Ohlsson, Claes
Publicado 2019

NEAT1 is overexpressed in Parkinson’s disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress

por Simchovitz, Alon, Hanan, Mor, Niederhoffer, Naomi, Madrer, Nimrod, Yayon, Nadav, Bennett, Estelle R., Greenberg, David S., Kadener, Sebastian, Soreq, Hermona
Publicado 2019

AhR–ROR-γt complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus

por Chuang, Huai-Chia, Chen, Yi-Ming, Chen, Ming-Han, Hung, Wei-Ting, Yang, Huang-Yu, Tseng, Yang-Hao, Tan, Tse-Hua
Publicado 2019

Macrophage-derived insulin-like growth factor-1 is a key neurotrophic and nerve-sensitizing factor in pain associated with endometriosis

por Forster, Rachel, Sarginson, Alexandra, Velichkova, Atanaska, Hogg, Chloe, Dorning, Ashley, Horne, Andrew W., Saunders, Philippa T. K., Greaves, Erin
Publicado 2019

The nucleoside diphosphate kinase NDK-1/NME1 promotes phagocytosis in concert with DYN-1/Dynamin

por Farkas, Zsolt, Petric, Metka, Liu, Xianghua, Herit, Floriane, Rajnavölgyi, Éva, Szondy, Zsuzsa, Budai, Zsófia, Orbán, Tamás I., Sándor, Sára, Mehta, Anil, Bajtay, Zsuzsa, Kovács, Tibor, Jung, Sung Yun, Afaq Shakir, Muhammed, Qin, Jun, Zhou, Zheng, Niedergang, Florence, Boissan, Mathieu, Takács-Vellai, Krisztina
Publicado 2019

NDUFAB1 protects against obesity and insulin resistance by enhancing mitochondrial metabolism

por Zhang, Rufeng, Hou, Tingting, Cheng, Heping, Wang, Xianhua
Publicado 2019

The RNA-binding protein ILF3 binds to transposable element sequences in SINEUP lncRNAs

por Fasolo, Francesca, Patrucco, Laura, Volpe, Massimiliano, Bon, Carlotta, Peano, Clelia, Mignone, Flavio, Carninci, Piero, Persichetti, Francesca, Santoro, Claudio, Zucchelli, Silvia, Sblattero, Daniele, Sanges, Remo, Cotella, Diego, Gustincich, Stefano
Publicado 2019

Comparative benefits of simvastatin and exercise in a mouse model of vascular cognitive impairment and dementia

por Trigiani, Lianne J., Royea, Jessika, Tong, Xin-Kang, Hamel, Edith
Publicado 2019

The Plasmodium falciparum Hsp70-x chaperone assists the heat stress response of the malaria parasite

por Day, Jemma, Passecker, Armin, Beck, Hans-Peter, Vakonakis, Ioannis
Publicado 2019

CAT1/SLC7A1 acts as a cellular receptor for bovine leukemia virus infection

por Bai, Lanlan, Sato, Hirotaka, Kubo, Yoshinao, Wada, Satoshi, Aida, Yoko
Publicado 2019

Temporal dynamics of learning-promoted synaptic diversity in CA1 pyramidal neurons

por Sakimoto, Yuya, Kida, Hiroyuki, Mitsushima, Dai
Publicado 2019

N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health

por Hofer, Dina C., Zirkovits, Gabriel, Pelzmann, Helmut J., Huber, Katharina, Pessentheiner, Ariane R., Xia, Wenmin, Uno, Kyosuke, Miyazaki, Toh, Kon, Kanta, Tsuneki, Hiroshi, Pendl, Tobias, Al Zoughbi, Wael, Madreiter-Sokolowski, Corina T., Trausinger, Gert, Abdellatif, Mahmoud, Schoiswohl, Gabriele, Schreiber, Renate, Eisenberg, Tobias, Magnes, Christoph, Sedej, Simon, Eckhardt, Matthias, Sasahara, Masakiyo, Sasaoka, Toshiyasu, Nitta, Atsumi, Hoefler, Gerald, Graier, Wolfgang F., Kratky, Dagmar, Auwerx, Johan, Bogner-Strauss, Juliane G.
Publicado 2019

Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D(3) and parathyroid hormone–induced osteoclastogenesis

por Conaway, H. Herschel, Henning, Petra, Lie, Antia, Tuckermann, Jan, Lerner, Ulf H.
Publicado 2019

Acyl-CoA synthetase 6 regulates long-chain polyunsaturated fatty acid composition of membrane phospholipids in spermatids and supports normal spermatogenic processes in mice

por Shishikura, Kyosuke, Kuroha, Sayoko, Matsueda, Shinnosuke, Iseki, Hachiro, Matsui, Takeshi, Inoue, Azusa, Arita, Makoto
Publicado 2019

Abnormal lacuno-canalicular network and negative correlation between serum osteocalcin and Cobb angle indicate abnormal osteocyte function in adolescent idiopathic scoliosis

por Chen, Huanxiong, Zhang, Jiajun, Wang, Yujia, Cheuk, Ka-Yee, Hung, Alec L. H., Lam, Tsz-Ping, Qiu, Yong, Feng, Jian Q., Lee, Wayne Y. W., Cheng, Jack C. Y.
Publicado 2019

Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulposus cell phenotype through cell shape

por Fearing, Bailey V., Jing, Liufang, Barcellona, Marcos N., Witte, Savannah Est, Buchowski, Jacob M., Zebala, Lukas P., Kelly, Michael P., Luhmann, Scott, Gupta, Munish C., Pathak, Amit, Setton, Lori A.
Publicado 2019

AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR

por Collodet, Caterina, Foretz, Marc, Deak, Maria, Bultot, Laurent, Metairon, Sylviane, Viollet, Benoit, Lefebvre, Gregory, Raymond, Frederic, Parisi, Alice, Civiletto, Gabriele, Gut, Philipp, Descombes, Patrick, Sakamoto, Kei
Publicado 2019

Catalytically inactive receptor tyrosine kinase PTK7 activates FGFR1 independent of FGF

por Shin, Won-Sik, Lee, Hae Won, Lee, Seung-Taek
Publicado 2019

Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis

por Colas, Romain A., Nhat, Le Thanh Hoang, Thuong, Nguyen Thuy Thuong, Gómez, Esteban A., Ly, Lucy, Thanh, Hai Hoang, Mai, Nguyen Thi Hoang, Phu, Nguyen Hoan, Thwaites, Guy E., Dalli, Jesmond
Publicado 2019

Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6

por Bianchi, Federica, Veggi, Daniele, Santini, Laura, Buricchi, Francesca, Bartolini, Erika, Lo Surdo, Paola, Martinelli, Manuele, Finco, Oretta, Masignani, Vega, Bottomley, Matthew J., Maione, Domenico, Cozzi, Roberta
Publicado 2019