Dendritic cells, engineered to overexpress 25-hydroxyvitamin D 1α-hydroxylase and pulsed with a myelin antigen, provide myelin-specific suppression of ongoing experimental allergic...

por Li, Chih-Huang, Zhang, Jintao, Baylink, David J., Wang, Xiaohua, Goparaju, Naga Bharani, Xu, Yi, Wasnik, Samiksha, Cheng, Yanmei, Berumen, Edmundo Carreon, Qin, Xuezhong, Lau, Kin-Hing William, Tang, Xiaolei
Publicado 2017

NAADP-mediated Ca(2+) signaling promotes autophagy and protects against LPS-induced liver injury

por Rah, So-Young, Lee, Young-Hoon, Kim, Uh-Hyun
Publicado 2017

Novel selective β(1)-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease

por Baker, Jillian G., Gardiner, Sheila M., Woolard, Jeanette, Fromont, Christophe, Jadhav, Gopal P., Mistry, Shailesh N., Thompson, Kevin S. J., Kellam, Barrie, Hill, Stephen J., Fischer, Peter M.
Publicado 2017

Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4

por Collins, Paul J., McCully, Michelle L., Martínez-Muñoz, Laura, Santiago, César, Wheeldon, James, Caucheteux, Stephan, Thelen, Sylvia, Cecchinato, Valentina, Laufer, Julia M., Purvanov, Vladimir, Monneau, Yoan R., Lortat-Jacob, Hugues, Legler, Daniel F., Uguccioni, Mariagrazia, Thelen, Marcus, Piguet, Vincent, Mellado, Mario, Moser, Bernhard
Publicado 2017

13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis

por Walker, Mary E., Souza, Patricia R., Colas, Romain A., Dalli, Jesmond
Publicado 2017

A TSPO ligand attenuates brain injury after intracerebral hemorrhage

por Li, Minshu, Ren, Honglei, Sheth, Kevin N., Shi, Fu-Dong, Liu, Qiang
Publicado 2017

Differential role of pannexin-1/ATP/P2X(7) axis in IL-1β release by human monocytes

por Parzych, Katarzyna, Zetterqvist, Anna V., Wright, William R., Kirkby, Nicholas S., Mitchell, Jane A., Paul-Clark, Mark J.
Publicado 2017

Gestational disruptions in metabolic rhythmicity of the liver, muscle, and placenta affect fetal size

por Papacleovoulou, Georgia, Nikolova, Vanya, Oduwole, Olayiwola, Chambers, Jenny, Vazquez-Lopez, Marta, Jansen, Eugene, Nicolaides, Kypros, Parker, Malcolm, Williamson, Catherine
Publicado 2017

Physiologic regulation of heart rate and blood pressure involves connexin 36–containing gap junctions

por Lall, Varinder K., Bruce, Gareth, Voytenko, Larysa, Drinkhill, Mark, Wellershaus, Kerstin, Willecke, Klaus, Deuchars, Jim, Deuchars, Susan A.
Publicado 2017

APMAP interacts with lysyl oxidase–like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion

por Pessentheiner, Ariane R., Huber, Katharina, Pelzmann, Helmut J., Prokesch, Andreas, Radner, Franz P. W., Wolinski, Heimo, Lindroos-Christensen, Josefine, Hoefler, Gerald, Rülicke, Thomas, Birner-Gruenberger, Ruth, Bilban, Martin, Bogner-Strauss, Juliane G.
Publicado 2017

PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease

por Dumont, Vincent, Tolvanen, Tuomas A., Kuusela, Sara, Wang, Hong, Nyman, Tuula A., Lindfors, Sonja, Tienari, Jukka, Nisen, Harry, Suetsugu, Shiro, Plomann, Markus, Kawachi, Hiroshi, Lehtonen, Sanna
Publicado 2017

Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei

por Macedo, Juan P., Currier, Rachel B., Wirdnam, Corina, Horn, David, Alsford, Sam, Rentsch, Doris
Publicado 2017

Cathepsin B as a potential cystatin M/E target in the mouse hair follicle

por Oortveld, Merel A. W., van Vlijmen-Willems, Ivonne M. J. J., Kersten, Ferry F. J., Cheng, Tsing, Verdoes, Martijn, van Erp, Piet E. J., Verbeek, Sjef, Reinheckel, Thomas, Hendriks, Wiljan J. A. J., Schalkwijk, Joost, Zeeuwen, Patrick L. J. M.
Publicado 2017

A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K(+) channels in carbon monoxide–induced proarrhythmic early afterdepolarizations

por Al-Owais, Moza M., Hettiarachchi, Nishani T., Kirton, Hannah M., Hardy, Matthew E., Boyle, John P., Scragg, Jason L., Steele, Derek S., Peers, Chris
Publicado 2017

Influence of intergenerational in utero parental energy and nutrient restriction on offspring growth in rural Gambia

por Eriksen, Kamilla G., Radford, Elizabeth J., Silver, Matt J., Fulford, Anthony J. C., Wegmüller, Rita, Prentice, Andrew M.
Publicado 2017

Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis

por Chen, Xiao, Zhi, Xin, Pan, Panpan, Cui, Jin, Cao, Liehu, Weng, Weizong, Zhou, Qirong, Wang, Lin, Zhai, Xiao, Zhao, Qingiie, Hu, Honggang, Huang, Biaotong, Su, Jiacan
Publicado 2017

Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence

por Benn, Andreas, Hiepen, Christian, Osterland, Marc, Schütte, Christof, Zwijsen, An, Knaus, Petra
Publicado 2017

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families

por Voloshanenko, Oksana, Gmach, Philipp, Winter, Jan, Kranz, Dominique, Boutros, Michael
Publicado 2017

The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling

por Galuppo, Paolo, Vettorazzi, Sabine, Hövelmann, Julian, Scholz, Claus-Jürgen, Tuckermann, Jan Peter, Bauersachs, Johann, Fraccarollo, Daniela
Publicado 2017

Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways

por Cheng, Jianghong, Zhong, Yanhong, Chen, Shuai, Sun, Yan, Huang, Lantang, Kang, Yujia, Chen, Baozhen, Chen, Gang, Wang, Fengli, Tian, Yingpu, Liu, Wenjie, Feng, Gen-Sheng, Lu, Zhongxian
Publicado 2017