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309741por Lu, Nian, Jiang, Yao-Fei, Xia, Wei-Xiong, Huang, Ying, Xie, Chuan-Miao, Xu, Cheng, Ye, Yan-Fang, Liu, Guo-Ying, Bei, Wei-Xin, Ke, Liang-Ru, Li, Wang-Zhong, Zhang, Cheng, Wang, Xin, Liu, Qin, Chen, Xi, Chen, Zi-Xiong, Xie, Changqing, Liang, Hu, Xiang, Yan-Qun“…Patients were enrolled and received sintilimab (200 mg) plus bevacizumab (7.5 mg/kg) intravenously every 3 weeks. Intention-to-treat population was included in primary endpoint analyses and safety analyses. …”
Publicado 2023
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309742“…It is also known as K2, spice, or fake weed, and these are popular as recreational drugs [Kourouni I et al. …”
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309743por Chen, Mengting, Ma, Liling, Yu, Huiqing, Huang, Shaoyi, Zhang, Junhui, Gong, Juan, Yang, Liejun, Chen, Lan, Luo, Haojun, Tian, Ling, Wang, Sixiong“…Patients were randomly (1:1) divided into two groups to receive four cycles (three weeks for each cycle) of programmed cell death-1 (PD-1) plus chemotherapy plus placebo (control group, n = 30) or to receive PD-1 plus chemotherapy plus JK5G postbiotics (JK5G group, n = 30). …”
Publicado 2023
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309744por Amariles, Pedro, Sabater-Hernández, Daniel, García-Jiménez, Emilio, Rodríguez-Chamorro, Miguel Ángel, Prats-Más, Rosa, Marín-Magán, Francisco, Galán-Ceballos, José Antonio, Jiménez-Martín, José, Faus, María José“…Study outcomes were assessed at baseline and at 16 and 32 weeks after randomization. The primary outcome measures were the proportions of patients achieving BP, TC, and BP/TC therapeutic goals (BP lower than 140/90 mm Hg for patients with uncomplicated hypertension and lower than 130/80 mm Hg for patients with diabetes, chronic kidney disease, or history of myocardial infarction or stroke; TC lower than 200 mg per dL for patients without CVD and lower than 175 mg per dL for patients with CVD). …”
Publicado 2012
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309745“…METHODS: Liquid medication measurements by patients or caregivers were observed in a convenience sample of community pharmacy patrons in Korea during a 2-week period in March 2011. Participants included all patients or caregivers (N = 300) who came to the pharmacy to buy over-the-counter liquid medication or to have a liquid medication prescription filled during the study period. …”
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309746“…Depressive symptoms were considered to be present if patients had a score on the Patient Health Questionnaire-2 of 3 or higher (the tool uses a Likert scale to determine the frequency [0 = not at all; 3 = nearly every day] that they had depressed mood and lack of pleasure in usual activities in the past 2 weeks; responses were summed and dichotomized). RESULTS: Analyses included 34 252 adolescents (12-16 years of age; mean [SD] age, 13.7 [0.8] years; 17 557 [51.3%] male, 7284 [21.3%] Asian or Pacific Islander, 2587 [7.6%] Black], 9061 [26.5%] Hispanic, 75 [0.2%] American Indian or Indigenous, 12 176 [35.5%] White, and 3069 [9%] other or unknown). …”
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309747por Toren, Eliana, Kepple, Jessica D., Coutinho, Kristen V., Poole, Samuel O., Deeba, Iztiba M., Pierre, Tanya H., Liu, Yanping, Bethea, Maigen M., Hunter, Chad S.“…Transcriptomic analysis of 14-week-old SSBP3(Δβ-cell) islets revealed a decrease in β-cell function gene expression (Ins, MafA, Ucn3), increased stress and dedifferentiation markers (Neurogenin-3, Aldh1a3, Gastrin), and shared differentially expressed genes between SSBP3, Ldb1, and Isl1 in adult β-cells. …”
Publicado 2023
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309748“…After confirmation, AG was administrated at a dose of 1 g/L in drinking water for two weeks. Urine was collected to measure the glomerular filtration rate (GFR), and the immune reactivity for AT(1) and AT(2) proteins was analyzed by immunoblotting. …”
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309749“…ABSTRACT: In this study, an eight-week feeding trial was performed to investigate the effects of different taurine supplementation levels (0.0% as control, 1.0%, 1.5%, 2.0%, 2.5%, and 3.0%) on the growth performance, lipid composition, and antioxidant ability in juvenile ivory shells Babylonia areolata. …”
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309750por Derbak, Hanane, Imre, Kálmán, Benabdelhak, Amira Chahrazad, Moussaoui, Mohamed, Kribeche, Amina, Kebbi, Rosa, Ayad, Abdelhanine“…ABSTRACT: The study was designed to evaluate the effects of the total alkaloid extract of Algerian Peganum harmala seeds on sexual behavior and male reproductive function. After two weeks of acclimatization, the male mice were randomly divided into four groups (seven mice in each group). …”
Publicado 2023
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309751por Kedir, Seman, Tamiru, Metekia, Tadese, Dawit Adisu, Takele, Lishan, Mulugeta, Melaku, Miresa, Ashenafi, Wamatu, Jane, Alkhtib, Ashraf, Burton, Emily“…For each treatment, six replicates were performed with four 24-week-old laying hens for a total of 96 chickens. …”
Publicado 2023
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309752“…Participating women were recruited in weeks 17 to 18 of pregnancy from 1999 to 2008 and were prospectively followed up after childbirth. …”
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309753por Lopes, Rodrigo T, da Rocha, Gustavo Chapetta, Svacina, Maria Adriana, Meyer, Björn, Šipka, Dajana, Berger, Thomas“…METHODS: We interviewed 312 participants recruited over the internet and randomized 189 participants with moderate to severe depression (according to the Patient Health Questionnaire–9 and a semistructured interview) to an intervention condition (treatment as usual plus immediate access to Deprexis for 90 days, n=94) or to a control condition (treatment as usual and delayed access to Deprexis, after 8 weeks, n=95). RESULTS: Participants from the immediate access group logged in at Deprexis an average of 14.81 (SD 12.16) times. …”
Publicado 2023
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309754por Silwal, Sashi, Parajuli, Kristina, Acharya, Astha, Ghimire, Ajnish, Pandey, Savita, Pandey, Ashok, Poudyal, Anil, Bista, Bihungum, Gyanwali, Pradip, Dhimal, Meghnath“…Approximately 10% of COVID-19 affected people have symptoms that last more than 3–4 weeks and experience numerous symptoms causing an impact on everyday functioning, social, and cognitive function. …”
Publicado 2023
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309755por Hamada, Yohhei, Quartagno, Matteo, Law, Irwin, Malik, Farihah, Bonsu, Frank Adae, Adetifa, Ifedayo M.O., Adusi-Poku, Yaw, D'Alessandro, Umberto, Bashorun, Adedapo Olufemi, Begum, Vikarunnessa, Lolong, Dina Bisara, Boldoo, Tsolmon, Dlamini, Themba, Donkor, Simon, Dwihardiani, Bintari, Egwaga, Saidi, Farid, Muhammad N., Celina G.Garfin, Anna Marie, Mae G Gaviola, Donna, Husain, Mohammad Mushtuq, Ismail, Farzana, Kaggwa, Mugagga, Kamara, Deus V., Kasozi, Samuel, Kaswaswa, Kruger, Kirenga, Bruce, Klinkenberg, Eveline, Kondo, Zuweina, Lawanson, Adebola, Macheque, David, Manhiça, Ivan, Maama-Maime, Llang Bridget, Mfinanga, Sayoki, Moyo, Sizulu, Mpunga, James, Mthiyane, Thuli, Mustikawati, Dyah Erti, Mvusi, Lindiwe, Nguyen, Hoa Binh, Nguyen, Hai Viet, Pangaribuan, Lamria, Patrobas, Philip, Rahman, Mahmudur, Rahman, Mahbubur, Rahman, Mohammed Sayeedur, Raleting, Thato, Riono, Pandu, Ruswa, Nunurai, Rutebemberwa, Elizeus, Rwabinumi, Mugabe Frank, Senkoro, Mbazi, Sharif, Ahmad Raihan, Sikhondze, Welile, Sismanidis, Charalambos, Sovd, Tugsdelger, Stavia, Turyahabwe, Sultana, Sabera, Suriani, Oster, Thomas, Albertina Martha, Tobing, Kristina, Van der Walt, Martie, Walusimbi, Simon, Zaman, Mohammad Mostafa, Floyd, Katherine, Copas, Andrew, Abubakar, Ibrahim, Rangaka, Molebogeng X.“…For alcohol drinking ≥ twice per week vs no alcohol drinking, the estimates were imprecise (OR 1.59, 95% CI 0.70–3.62) for subclinical TB and OR 1.43, 95% CI 0.59–3.46 for symptomatic TB). …”
Publicado 2023
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309756“…While cerebritis, intracranial abscesses, and infarcts can be seen early in the disease due to the angioinvasive nature, perineural spread and skull base infiltration are seen 3–4 weeks after disease onset. Exaggerated soft-tissue enhancement in the post-operative bed after debridement can be a normal finding and must not be interpreted as disease progression.…”
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309757por Mitchell, Ellen Siobhan, Fabry, Alexander, Ho, Annabell Suh, May, Christine N, Baldwin, Matthew, Blanco, Paige, Smith, Kyle, Michaelides, Andreas, Shokoohi, Mostafa, West, Michael, Gotera, Kim, El Massad, Omnya, Zhou, Anna“…The index date was defined as the first day of a 3-month treatment window during which Noom Weight was used at least once per week on average. Inverse probability treatment weighting was used to balance sociodemographic covariates between the 2 cohorts. …”
Publicado 2023
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309758por Jiao, Anqi, Sun, Yi, Avila, Chantal, Chiu, Vicki, Slezak, Jeff, Sacks, David A., Abatzoglou, John T., Molitor, John, Chen, Jiu-Chiuan, Benmarhnia, Tarik, Getahun, Darios, Wu, Jun“…Short-term exposures were represented by binary variables of heatwaves with 9 different definitions (combining percentile thresholds with 3 durations; ie, ≥2, ≥3, and ≥4 consecutive days) during the last gestational week. MAIN OUTCOMES AND MEASURES: The primary outcome was SMM during delivery hospitalization, measured by 20 subconditions excluding blood transfusion. …”
Publicado 2023
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309759“…STUDY DESIGN: In a single-center cohort observational study design (data collection done from 1984–1988, analysis done in 2022), a prospective cranial ultrasound screening study (1984–1988) was carried out on 5,301 live-born infants, including 571 (10.8%) preterm infants (≤36 weeks gestation), on the day of discharge of the mother at 5 to 8 days postpartum from a level 3 perinatal center. …”
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309760por Mwacalimba, Kennedy, Hillier, Andrew, Rosenbaum, Michele, Brennan, Christopher, Amodie, Deborah“…Oclacitinib therapy was also associated with an 83% reduction in concomitant treatments, including a 100% reduction in systemic antimicrobial therapy over eight weeks. DISCUSSION: Dogs receiving oclacitinib showed no increase in antimicrobial therapy transactions compared to glucocorticoid recipients at the initial pyoderma diagnosis. …”
Publicado 2023
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