“…Immunophenotyping of peripheral blood was performed before the third dose of tozinameran (timepoint-1) and four weeks later (timepoint-2) to quantify the absolute counts of lymphocyte subpopulations, including CD3(+)CD4(+) T cells, CD3(+)CD8(+) T cells, B cells, and NK cells. …”
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“…Patient reported outcome measures were collected pre-operatively and at regular intervals after surgery (6 weeks, 3 months, 6 months, and then yearly). Visual analog scale for pain (VAS), Hip disability and Osteoarthritis (HOOS) junior, and Patient Reported Outcomes Measurement Information System (PROMIS) Physical Function scores were collected via electronic data capture. …”
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“…Two dosages of AK112 (10 or 20 mg/kg) were examined in each cohort, and the drug was administered intravenously on day 1 of each 3-week treatment cycle. The primary endpoints were the investigator-assessed objective response rate (ORR) and safety. …”
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“…METHODS: Healthy murine aortas were harvested from 10- to 14-week-old C57/Bl6J male and female mice and compared under different storage protocols (24 hours) to immediate arterial testing. …”
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“…Each participant drank two beverages, one containing a blend of three food-derived oligopeptides (treatment, 0.5 g/kg body weight in total) and the other without (control), with a 2-week washout period between two experiments. The cyclists completed a one-day pattern protocol that consisted of intraday fasting, 30 min of sitting still, 85 min of prolonged exercise plus a 5-min sprint (PE), a short recovery period of 60 min, a 20-min time trial (TT), and recovery till next morning. …”
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“…CASE DESCRIPTION: A 49-year-old female office worker presented to A&E with a two-week history of arthralgia and fatigue. Over the past two days, she had also noticed the development of periorbital swelling and a rash on her eyelids and her upper back. …”
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“…Prior to starting biologics, his asthma had been poorly controlled with salbutamol, Fostair, tiotropium inhalers and low-dose corticosteroids. Within weeks, he developed symmetrical arthralgias involving small joints, particularly his wrists and knuckles, as well as significant early morning stiffness lasting more than one hour. …”
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“…As of December 2022, they have received evinacumab 15 mg/kg intravenously every four weeks for a mean of 12.2 months (SD = 11.3). Their mean incremental LDL-C reduction is 49.4% (SD = 8.9) on evinacumab along with reduced apheresis frequency for those on serial apheresis. …”
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“…The T4DM study randomized 1007 men (age 50-74 yr, waist ≥95 cm, serum T ≤14.0 nmol/L, no pathological hypogonadism) with impaired glucose tolerance or newly diagnosed type 2 diabetes to T undecanoate (1000 mg) or matching placebo injections every 12 weeks for 24 months with a lifestyle program. At study’s end, T treatment reduced OGTT diabetes diagnosis by 40% without change in HbA(1)C. …”
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“…Each cycle, administered four weeks apart, comprised Irinotecan 50 mg/m(2)/day intravenously (IV) plus Temozolomide 150 mg/m(2)/day orally (days 1–5); naxitamab 2.25 mg/kg/day IV on days 2, 4, 8 and 10, (total 9 mg/kg or 270 mg/m(2) per cycle), and GM-CSF 250 mg/m(2)/day subcutaneously was used (days 6–10). …”
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“…During this period, the most favorable growth parameters were observed in groups D2 (420 ± 91 g) and PC (407 ± 103 g), in which piglets obtained a mixture of pancreatic enzymes (lipase, amylase, and protease) at 3 weeks of age, and significantly higher weight gain and feed intake were observed compared with groups NC (378 ± 114 g) and D1 (381 ± 96 g) (p ≤ 0.007). …”
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“…METHODS: The study cohort consisted of Chinese KPSC members aged ≥50 years who received two doses of RZV 4 weeks to ≤6 months apart; second doses were accrued from 6/1/2018 to 12/31/2020. …”
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“…Samples were acquired on the cytometer within a week of staining and analyzed using FlowJo 10.8.0 software. …”
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“…Tumor regression induced by intratumoral IL-2 application may be a fast process (requiring about a week) in the case of a highly vascular tumor since IL-2 induces vascular leakage/edema and consequently massive tumor necrosis. …”
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“…The patient was discharged to his usual residence a week later and follow-up was organised with both the endocrinologists and ophthalmologists. …”
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“…Previous studies in our lab have shown that MIN6 cells encapsulated as aggregates maintain their viability throughout 4 weeks of culture in 20% oxygen. MIN6 aggregates cultured at 2 or 1% oxygen showed both signs of necrotic cells (still about 85-90% viable) by staining with ethidium bromide as well as morphological changes relative to cells in 20% oxygen. …”
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“…In the New Jersey DoD runs, repeated clusters indicated a 10-week GI outbreak at Fort Dix; adding VA data that dominated the record counts gave the same clusters with no added cases, so the DoD event was probably self-contained. …”
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“…Two thirds of the EDs reported a lag time of less than one week between the visit and assignment of diagnosis codes. …”
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“…Covariates for month and day of week were included to control for temporal trends in ED visits. …”
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“…INTERVENTION: Eligible patients were randomized (1:1:1) to receive a once-daily, optimized dose of lisdexamfetamine (30, 50 or 70 mg/day), placebo or OROS-MPH (18, 36 or 54 mg/day) for 7 weeks. MAIN OUTCOME MEASURES: In this post hoc analysis, efficacy was assessed using the ADHD-RS-IV and Clinical Global Impressions-Improvement (CGI-I) scale. …”
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