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311701por Mitchell, Kirstin R, Mercer, Catherine H, Ploubidis, George B, Jones, Kyle G, Datta, Jessica, Field, Nigel, Copas, Andrew J, Tanton, Clare, Erens, Bob, Sonnenberg, Pam, Clifton, Soazig, Macdowall, Wendy, Phelps, Andrew, Johnson, Anne M, Wellings, Kaye“…Associations were also noted with engaging in fewer than four sex acts in the past 4 weeks (3·13 [2·58–3·79] and 3·38 [2·80–4·09]), having had same sex partners (2·28 [1·56–3·35] and 1·60 [1·16–2·20]), paying for sex (in men only; 2·62 [1·46–4·71]), and higher numbers of lifetime sexual partners (in women only; 2·12 [1·68–2·67] for ten or more partners). …”
Publicado 2013
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311702Genotoxicity of charged particles of importance in space flight using murine kidney epithelial cellspor Kronenberg, Amy, Gauny, Stacey, Grossi, Gianfranco, Dan, Cristian, Grygoryev, Dmytro, Turker, Mitchell“…The irradiated kidney cells were also seeded in mutation assays within 1 week post-irradiation to determine the Aprt mutant fraction at the earliest time post-exposure. …”
Publicado 2014
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311703por Tilbrook, H.E., Hewitt, C.E., Aplin, J.D., Semlyen, A., Trewhela, A., Watt, I., Torgerson, D.J.“…SUMMARY OF BACKGROUND DATA: A large multicentre RCT using intention-to-treat (ITT) analysis found that participants with chronic low back pain who were offered a 12-week progressive programme of yoga plus usual GP care had better back function than those offered usual GP care alone. …”
Publicado 2014
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311704por Pace, David, Khatami, Ameneh, McKenna, Jennifer, Campbell, Danielle, Attard-Montalto, Simon, Birks, Jacqueline, Voysey, Merryn, White, Catherine, Finn, Adam, Macloed, Emma, Faust, Saul N, Kent, Alison Louise, Heath, Paul T, Borrow, Ray, Snape, Matthew D, Pollard, Andrew J“…Participants Healthy infants aged 6-12 weeks followed up until age 24 months. Interventions In the priming phase of the trial 509 infants were randomised in a 10:10:7:4 ratio into four groups to receive either a single MenC-cross reacting material 197 (CRM) dose at 3 months; two doses of MenC-CRM at 3 and 4 months; a single MenC-polysaccharide-tetanus toxoid (TT) dose at 3 months; or no MenC doses, respectively. …”
Publicado 2015
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311705por Lu, Wenbin, Xie, ZhuoYing, Tang, Yong, Bai, Ling, Yao, Yuyu, Fu, Cong, Ma, Genshan“…Increased survival of transplanted MSCs (13±3/mm(2) vs. 4±1/mm(2), p<0.001) and significantly decreased TdT-mediated dUTP nick end labeling (TUNEL)(+) cardiac myocytes (17.44%±6.26% vs. 39.49%±13.28%, p<0.001) were then identified in the infarct zone three days after AMI induction in the PMSNs-siCCR2 group. Three weeks after MSC injection, significant increases were observed in the vascular density (235.5±39.6/mm(2) vs. 147.4±20.3/mm(2), p<0.001) and the cardiac myosin-positive area (21.7%±8.4% vs. 13.2%±4.4%, p<0.001) of the infarct border zone. …”
Publicado 2015
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311706por Borneman, Tami“…They walked for miles into Hungary, where they found shelter in a convent for several weeks. The Mother Superior collected money so he could take the train to Budapest and arranged for him to stay in a Catholic home. …”
Publicado 2014
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311707por Wilkins, Anna, Mossop, Helen, Syndikus, Isabel, Khoo, Vincent, Bloomfield, David, Parker, Chris, Logue, John, Scrase, Christopher, Patterson, Helen, Birtle, Alison, Staffurth, John, Malik, Zafar, Panades, Miguel, Eswar, Chinnamani, Graham, John, Russell, Martin, Kirkbride, Peter, O'Sullivan, Joe M, Gao, Annie, Cruickshank, Clare, Griffin, Clare, Dearnaley, David, Hall, Emma“…UCLA Prostate Cancer Index (UCLA-PCI), including Short Form (SF)-36 and Functional Assessment of Cancer Therapy-Prostate (FACT-P), or Expanded Prostate Cancer Index Composite (EPIC) and SF-12 quality-of-life questionnaires were completed at baseline, pre-radiotherapy, 10 weeks post-radiotherapy, and 6, 12, 18, and 24 months post-radiotherapy. …”
Publicado 2015
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311708por Farrar, Diane, Fairley, Lesley, Santorelli, Gillian, Tuffnell, Derek, Sheldon, Trevor A, Wright, John, van Overveld, Lydia, Lawlor, Debbie A“…METHODS: We used data (including results of a 26–28 week gestation oral glucose tolerance test) of women from the Born in Bradford study, a prospective study that recruited women attending the antenatal clinic at the Bradford Royal Infirmary, UK, between 2007 and 2011 and who intended to give birth to their infant in that hospital. …”
Publicado 2015
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311709por Heyderman, Robert S, Madhi, Shabir A, French, Neil, Cutland, Clare, Ngwira, Bagrey, Kayambo, Doris, Mboizi, Robert, Koen, Anthonet, Jose, Lisa, Olugbosi, Morounfolu, Wittke, Frederik, Slobod, Karen, Dull, Peter M“…Participants were divided into three groups on the basis of their HIV infection status (no infection, infection and high CD4 cell count [>350 cells per μL], and infection and low CD4 cell count [>50 to ≤350 cells per μL]) and received a 5 μg dose of glycoconjugate GBS vaccine (serotypes Ia, Ib, and III, with CRM(197) [Novartis Vaccines, Siena, Italy]) intramuscularly at 24–35 weeks' gestation. GBS serotype-specific antibody concentrations were measured before vaccination (day 1), day 15, day 31, and at delivery, and in infants at birth and day 42 of life. …”
Publicado 2016
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311710por Tang, Lydia Shuk Yee, Masur, Jack, Sims, Zayani, Nelson, Amy, Osinusi, Anu, Kohli, Anita, Kattakuzhy, Sarah, Polis, Michael, Kottilil, Shyam“…There was no statistically significant difference in pill counts, adherence to study visits between groups, nor mean serum concentrations of GS-331007 for each group at week 2 of treatment (P = 0.72). Among patients with HIV co-infection, pre-treatment BDI scores were similar among patients treated with sofosbuvir, and those treated with interferon (sofosbuvir-based 5.24, IFN-based 6.96; P = 0.14); however, a dichotomous effect on was observed during treatment. …”
Publicado 2016
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311711Epigenetics of amphetamine-induced sensitization: HDAC5 expression and microRNA in neural remodeling“…METHODS: We compared the expression of HDAC5 mRNA in an acute exposure paradigm (in which animals experienced a single drug exposure [A1]) and in a chronic-abstinence-challenge paradigm (in which animals were exposed to the drug once every other day for seven doses, then underwent 2 weeks of abstinence followed by a challenge dose [A7WA]). …”
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311712por Neal, Joel W., Dahlberg, Suzanne E., Wakelee, Heather A., Aisner, Seena C., Bowden, Michaela, Huang, Ying, Carbone, David P., Gerstner, Gregory J., Lerner, Rachel E., Rubin, Jerome L., Owonikoko, Taofeek K., Stella, Philip J., Steen, Preston D., Khalid, Ahmed Ali, Ramalingam, Suresh S.“…Imaging was performed every 8 weeks. At the time of radiographic progression, there was optional crossover for patients in either single agent arm to receive combination therapy. …”
Publicado 2016
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311713“…The patients in the duloxetine group received doxazosin 4 mg + duloxetine 30 mg once a day, and the dosage of duloxetine was increased to 60 mg after a week. The patients in the doxazosin group received doxazosin 4 mg once a day. …”
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311714por Dandona, Rakhi, Kumar, G. Anil, Kumar, Amit, Singh, Priyanka, George, Sibin, Akbar, Mohammad, Dandona, Lalit“…A stillbirth was defined as a foetal death with a gestation period of ≥28 weeks wherein the foetus did not show any sign of life. …”
Publicado 2017
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311715por Silas, Diana Rebecca, Adler, Kelly, Kenney, Raymond James, Messing, Susan, Giordano, Brian D.“…This was accomplished by determining the regression of these outcomes from pre-op measurement to the first follow-up visit and then from the first follow-up visit through the 5-7 week, 3-4 month, 5-7 month and 10-14 month visits. …”
Publicado 2017
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311716por Lopez, H. L., Habowski, S. M., Sandrock, J. E., Raub, B., Kedia, A., Bruno, E. J., Ziegenfuss, T. N.“…METHODS: One-hundred and five (105) overweight, apparently healthy male and female subjects (35–70 years of age) were pre-screened and randomized to one of three groups for 84 days: placebo, AyuFlex1 (250 mg twice daily) or AyuFlex2 (500 mg twice daily) in a randomized, double-blind, placebo-controlled design. A two-week placebo lead-in period was used to improve data quality/validity. …”
Publicado 2017
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311717“…For over two months he was in a critical medical condition because of septicaemia, he suffered acute pain, and every two weeks had a series of surgeries (skin transplantations). …”
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311718por Alistar, Angela, Morris, Bonny B., Desnoyer, Rodwige, Klepin, Heidi D., Hosseinzadeh, Keyanoosh, Clark, Clancy, Cameron, Amy, Leyendecker, John, D’Agostino, Ralph, Topaloglu, Umit, Boteju, Lakmal W., Boteju, Asela R., Shorr, Rob, Zachar, Zuzana, Bingham, Paul M., Ahmed, Tamjeed, Crane, Sandrine, Shah, Riddhishkumar, Migliano, John J., Pardee, Timothy S., Miller, Lance, Hawkins, Gregory, Jin, Guangxu, Zhang, Wei, Pasche, Boris“…The starting dose of CPI-613 was 500 mg/m(2)/day; the dose level was then escalated by doubling the previous dose if there was no toxicity greater than Grade 2 within 4 weeks attributed as probably or definitely related to CPI-613. …”
Publicado 2017
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311719“…They had a lower employment rate (33.3% vs 54.2%, P = 0.016) and amongst those who were employed less number of working hours per week (median of 23 vs 40, P = 0.005). They reported higher number of hospitalizations in the last 1 year (mean ± SE of mean of 2.90 ± 0.77 vs 1.26 ± 0.23, P = 0.047). …”
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311720“…Non-responders were crossed over to the other treatment after a 6-week break. Cycles were initially monitored with ultrasound follicle tracking then mid-luteal serum progesterone measurement in subsequent cycles. …”
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