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311801“…Furthermore, sub-group analyses were conducted by separating studies into those that examined the effects of CrM as an acute training response (i.e., after one muscle-damaging exercise bout) and those that examined the chronic training response (i.e., examining the acute response after the last training session following several weeks of training). RESULTS: According to the meta-analysis, the CrM group exhibited significantly lower indirect muscle damage markers (i.e., creatine kinase, lactate dehydrogenase, and/or myoglobin) at 48–90 h post-exercise for the acute training response (SMD − 1.09; p = 0.03). …”
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311802“…The results showed that the scores of the four dimensions of emotion regulation in the first two groups were less than 2 points, and the difference was not statistically significant (P > 0.05). After 8 weeks of emotion regulation intervention, the average scores of initiative, negotiation psychological mastery, tension evaluation and conflict attitude in the intervention group were significantly higher than those in the control group (P < 0.01). …”
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311803“…MRC-5 cell line was obtained from a 14 week old fetal normal lung tissue. Quantitative analysis of the proteome and phosphorylated proteome in these normal lung cells and lung cancer cells with different metastatic capacities can identify key pathways and regulatory proteins associated with lung cancer metastasis and progression. …”
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311804por Sansone, Nathália MS, Boschiero, Matheus N, Valencise, Felipe E, Palamim, Camila VC, Marson, Fernando AL“…METHODS: We performed an epidemiological analysis for the first 67 epidemiological weeks of the COVID-19 pandemic in Brazil (from February 22, 2020, to April 04, 2021) using the data available at OpenDataSUS of the Brazilian Ministry of Health, a data set containing data from Brazilian hospitalized individuals. …”
Publicado 2022
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311805por Fizazi, Karim, Retz, Margitta, Petrylak, Daniel P, Goh, Jeffrey C, Perez-Gracia, Jose, Lacombe, Louis, Zschäbitz, Stefanie, Burotto, Mauricio, Mahammedi, Hakim, Gravis, Gwenaelle, Bastos, Diogo Assed, McCune, Steven L, Vázquez Limón, Juan Carlos, Kwan, Edmond M, Castellano, Daniel, Fléchon, Aude, Saad, Fred, Grimm, Marc-Oliver, Shaffer, David R, Armstrong, Andrew J, Bhagavatheeswaran, Prabhu, Amin, Neha P, Ünsal-Kaçmaz, Keziban, Wang, Xuya, Li, Jun, Loehr, Andrea, Pachynski, Russell K“…Patients received nivolumab 480 mg every 4 weeks plus rucaparib 600 mg two times per day (nivolumab dosing ≤2 years). …”
Publicado 2022
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311806por Liu, Wenjun, Xiong, Hao, Wang, Wei, Chen, Shuai, Li, Fengfeng, Liu, Junjian, Yan, Hede, Zhang, Jingwei, Qian, Yun, Fan, Cunyi“…Outcomes were assessed at 6 weeks, 6 months, and 1 year postoperatively and annually thereafter. …”
Publicado 2022
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311807“…RCTs in patients with insomnia disorder applying trazodone in one arm of interventions at least 1 week, and reporting PSG parameters in the outcomes were eligible. …”
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311808“…The patients with previous history of pulmonary tuberculosis who presented with symptoms of cough, hemoptysis, fever, shortness of breath, chest pain, and weight loss of ˃12-week duration were enrolled in the study. Relevant investigations including blood tests, chest imaging, sputum examination for bacterial infections, fungal (KOH mount), and tuberculosis (AFB smear, CBNAAT, mycobacterial cultures) were done. …”
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311809“…Following a multi-disciplinary team discussion, the patient was treated with rituximab 500mg two weeks apart with 100mg of methylprednisolone as premedication prior to the infusions. …”
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311810“…Her main disabling SSs symptom was refractory belching, intermittent dysphagia and reflux disease resulting in poor oral intake and resultant malnutrition. She had 4-week trial of antibiotics to treat for presumptive small intestine bacterial overgrowth (SIBO) due to persistent belching but had no evident improvement. …”
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311811por Barui, Sanghita, Sanyal, Parikshit, Rajmohan, K. S., Malik, Ajay, Dudani, Sharmila“…The training set was also circulated to medical students (MS) of the college for a week. An online quiz, consisting of a random selection of 100 images from the validation set, was conducted on students (after obtaining informed consent) who volunteered for the study. 66 students participated in the quiz, providing 6557 responses. …”
Publicado 2022
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311812por Makhlouf, Yasmine, Ferjani, Hanene Lassoued, Ben Ammar, Lobna, Nessib, Dorra B, triki, Wafa, Maatallah, Kaouther, Kaffel, Dhia, Hamdi, Wafa“…Methotrexate (MTX) was prescribed in 30% of cases with a mean dose of 7.91 mg/week [7.5–10]. Only one patient was on sulfasalazine. …”
Publicado 2022
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311813por Fietze, Ingo, Bassetti, Claudio L. A., Mayleben, David W., Pain, Scott, Seboek Kinter, Dalma, McCall, William V.“…Daridorexant 50 mg progressively improved IDSIQ total and domain scores from week 1 onwards similarly in both groups; daridorexant 25 mg improved IDSIQ scores, but only in younger adults. …”
Publicado 2022
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311814por Bahramkhani-Zaringoli, Leili, Mirzaei-Alamouti, Hamidreza, Aschenbach, Jörg R., Vazirigohar, Mina, Patra, Amlan Kumar, Jafari-Anarkooli, Iraj, Ganjkhanlou, Mahdi, Alipour, Daryoush, Mansouryar, Morteza“…The highest differences of DMI between fat-supplemented and CON-lambs were observed in week 3 of the adaptation period (p = 0.010). PALM- or SOY-supplementation lowered DM and NDF digestibility compared with CON (p < 0.05), and SOY caused the lowest organic matter (OM) digestibility compared with CON and PALM lambs (62.0 vs. 67.6 and 66.9; p < 0.05). …”
Publicado 2022
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311815por Vasquez, Daniela N., Giannoni, Roberto, Salvatierra, Adriana, Cisneros, Karina, Lafosse, Diego, Escobar, María F., Montenegro, Martín, Juárez, Paula, Visani, Lucía, Mandich, Verónica, Barrozo, Erika, Kirschbaum, Mariana, Das Neves, Andrea V., Valenti, María F., Canseco, María C., Romero, Ignacio, Macharé, Pedro, Marquez, Ana K., Rodriguez, Eva, Palacio, Cristina, Rapela, Laura, Amillategui Scenna, José M., Nuñez, Rosshanna, Torres, Sebastián, González, Miguel A., Franconieri, Lorena, Nasner, Daniela, Okurzaty, Patricia, Plotnikow, Gustavo A., Intile, Alfredo D.“…RESULTS: Ninety-one patients were admitted to 21 ICUs at 29.2 ± 4.9 weeks; 63 patients (69%) delivered in ICU. Maximal ventilatory support was as follows: IMV, 69 patients (76%); high-flow nasal cannula, 20 patients (22%); and noninvasive mechanical ventilation, 2 patients (2%). …”
Publicado 2023
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311816por Drummond, Rosa, Patel, Mayuri, Myers, Madalyn, Ritter, Alexandra, Hurvitz, Julie A., Goetzinger, Katherine R., Crimmins, Sarah D.“…OBJECTIVE: With emerging data on the safety of 39-week inductions, we aimed to: (1) determine if Class III obesity, including morbid obesity, is an independent risk factor for nonachievement of complete dilation and vaginal delivery after induction of labor, (2) evaluate the characteristics of the induction of labor course and immediate complications, and (3) evaluate the number of induction agents necessary to be associated with vaginal deliveries. …”
Publicado 2022
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311817“…Mice were placed on a high sodium diet (to suppress physiologic renin) and orally provided the GqDREADD ligand, clozapine N-oxide (CNO; n=10) or control (n=8) for 6 weeks followed by collection of blood and adrenals. …”
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311818por Jain, Arad, Patel, Tushar P, Altman, Elizabeth K, Tugarinov, Nicol, Levi, Noah J, Elizondo, Diana M, Arner, Brooke E, Roberson, Robin B, Caron, Alexandre, Elmquist, Joel K, Yanovski, Jack A“…MC3R reactivation in the liver caused a partial recovery from the obesity phenotype of Mc3rtb/tb mice exposed to 45 kcal% energy fat diet for 12 weeks, particularly in female mice. Recovery of hepatic Mc3r was sufficient to partially reverse the increased percentage fat mass of Mc3rtb/tb (Mc3rtb/tb: n=11, 55.3 ± 0.8% (SEM); Mc3rtb/tb, Alb-Cre+/+: n=13, 52.4 ± 0.8%; BL/6: n=14, 39.7 ± 2.1%, p=0. 017). …”
Publicado 2022
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311819por Weldearegay, Haftom Gebrehiwot, Kahsay, Alemayehu Bayray, Godefay, Hagos, Petrucka, Pammla, Medhanyie, Araya Abrha“…The first round of data collection (baseline) took place two weeks prior the inauguration of the intervention, 05 October to 04 November 2019. …”
Publicado 2022
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311820por Zhu, Xiaofei, Liu, Wenyu, Cao, Yangsen, Ju, Xiaoping, Zhao, Xianzhi, Jiang, Lingong, Ye, Yusheng, Zhang, Huojun“…METHODS: In this open-label, randomised, controlled, phase 2 trial, eligible patients with pancreatic ductal adenocarcinoma characterized by mutant KRAS and positive immunohistochemical staining of PD-L1 and documented post-operative local recurrence were randomly assigned using an interactive voice or web response system, without stratification, to receive stereotactic body radiation therapy (SBRT) with doses ranging from 35 to 40Gy in five fractions, pembrolizumab 200 mg every three weeks and oral trametinib 2 mg once daily (SBRT + K + M) or SBRT and gemcitabine (1000 mg/m(2)) on day 1 and 8 of each 21-day cycle (SBRT + G) until disease progression in our hospital in China. …”
Publicado 2022
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