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  1. 1741
    “…In Capan-1 tumour-bearing mice rucaparib accumulated and was retained in the tumours, and PARP was inhibited for 7 days following a single dose of 10 mg kg(−1) i.p or 150 mg kg(−1) p.o. by 70% and 90%, respectively. Weekly dosing of 150 mg kg(−1) p.o once a week was as effective as 10 mg kg(−1) i.p daily for five days every week for 6 weeks in delaying Capan-1 tumour growth. …”
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    Tumour cell retention of rucaparib, sustained PARP inhibition and efficacy of weekly as well as daily schedules
  2. 1742
    “…CONCLUSIONS: We found that potential PA admissions among persons with PD varied systematically by day of the week, with a significant peak on weekends and holidays.…”
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    Weekly and Holiday-Related Patterns of Panic Attacks in Panic Disorder: A Population-Based Study
  3. 1743
    “…We expected that the course of 18 weekly inhibitory LF rTMS applied to the dorsolateral prefrontal cortex (DLPFC) would enhance autonomic balance by facilitating frontal inhibition of limbic activity thus resulting in decreased overall heart rate (HR), increased HRV (in a form of increased HF power), decreased LF power (resulting in decreased LF/HF ratio), and decreased SCL. …”
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    Effects of weekly low-frequency rTMS on autonomic measures in children with autism spectrum disorder
  4. 1744
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    Phase I study of combination therapy with weekly paclitaxel and cyclophosphatamide for advanced or recurrent breast cancer
  5. 1745
    “…Here, we treated obese male mice on high-fat diet with rapamycin given intermittently: either weekly (once a week) or alternating bi-weekly (three injections every other week). …”
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    Weekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat diet
  6. 1746
    “…PURPOSE: The purpose of this study was to evaluate the safety and efficacy of low-dose-intensity bevacizumab and weekly irinotecan as salvage treatment for patients with platinum- and taxanes-resistant advanced epithelial ovarian cancer. …”
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    Low-dose-intensity bevacizumab with weekly irinotecan for platinum- and taxanes-resistant epithelial ovarian cancer
  7. 1747
    “…If stroke occurs frequently on a specific day of the week, it is assumed that other factors, that is, ‘triggering factors’, induce stroke. …”
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    Weekly variations of stroke occurrence: an observational cohort study based on the Kyoto Stroke Registry, Japan
  8. 1748
    “…METHODS: Patients received intravenous irinotecan 175 mg/m(2) on day 1 and oral capecitabine 1000 mg/m(2) (800 mg/m(2) for patients >65 years of age) twice daily on days 2–8, followed by a 1-week rest, and bevacizumab 5 mg/kg as an intravenous infusion on day 1 every 2 weeks. …”
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    Capecitabine and irinotecan with bevacizumab 2-weekly for metastatic colorectal cancer: the phase II AVAXIRI study
  9. 1749
    “…The aim of the present study was to explain changes in bone turnover markers using once-weekly teriparatide with a simulation model. Temporary increases in bone formation markers and subsequent decreases were observed during once-weekly teriparatide treatment for 72 weeks. …”
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    New simulation model for bone formation markers in osteoporosis patients treated with once-weekly teriparatide
  10. 1750
    “…Since 2012, a new generation GLP-1 agent, exenatide once weekly (QW), has been available for patients with T2DM in the USA, but not as yet in the People’s Republic of China. …”
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    Exenatide once-weekly injection for the treatment of type 2 diabetes in Chinese patients: current perspectives
  11. 1751
    “…RESULTS: MPR over 5 years was 20.8 and 60.9 % for daily and weekly BPs (p < 0.001), respectively. MPR over 1 year was 38.6, 70.6, and 77.7 % for daily, weekly, and monthly BPs (P < 0.001), respectively. …”
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    Compliance and persistence with daily, weekly, and monthly bisphosphonates for osteoporosis in Japan: analysis of data from the CISA
  12. 1752
    “…Herein, we report the case of a Japanese woman with advanced EMPD successfully controlled by monthly but not weekly docetaxel therapy. We also demonstrate the possibility that a monthly regimen of docetaxel is a more effective and optimal schedule than a weekly one through this case report.…”
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    A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy
  13. 1753
    “…The volume of fluid compartments was measured by bioimpedance. RESULTS: Weekly dialytic removal of 12.79 ± 8.71 mmol calcium was found in 17 patients, whereas 9.48 ± 8.07 mmol calcium was absorbed per week from dialysis fluid in 8 patients. …”
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    Quantification of Dialytic Removal and Extracellular Calcium Mass Balance during a Weekly Cycle of Hemodialysis
  14. 1754
    “…The cumulative probability was 18.9%. The weekly miscarriage rate declined steadily with increasing gestation until approximately 20 weeks. …”
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    Weekly miscarriage rates in a community-based prospective cohort study in rural western Kenya
  15. 1755
    por Gim, Mi-Na, Choi, Jung-Hyun
    Publicado 2016
    “…[Purpose] The present study examined the effect of individual weekly exercise time on resting metabolic rate and VO(2max) (maximal oxygen uptake), which are important components of individual health indexes. …”
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    The effects of weekly exercise time on VO(2max) and resting metabolic rate in normal adults
  16. 1756
    “…The aim of the present study was to compare weekly physical activity (PA) and obesity-related markers in athlete and non-athlete university students. …”
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    Weekly physical activity patterns of university students: Are athletes more active than non-athletes?
  17. 1757
    “…INTRODUCTION: Randomized studies have shown that bortezomib (BTZ) can be given weekly via intravenous (IV) route or twice weekly via subcutaneous (SC) route with lower neuropathy risk and no loss of anti-myeloma efficacy compared to original standard IV twice weekly schedule. …”
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    Neuropathy and efficacy of once weekly subcutaneous bortezomib in multiple myeloma and light chain (AL) amyloidosis
  18. 1758
    por Kang, Mo-Yeol, Hong, Yun-Chul
    Publicado 2017
    “…OBJECTIVES: To investigate the association between spouse weekly working hours (SWWH) and the estimated 10-years risk of cardiovascular disease (CVD). …”
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    Crossover effect of spouse weekly working hours on estimated 10-years risk of cardiovascular disease
  19. 1759
    “…Several GLP-1 receptor agonists are available as weekly injections. These medications vary in their injection delivery systems, and these differences could impact quality of life and treatment preference. …”
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    Health state utilities associated with attributes of weekly injection devices for treatment of type 2 diabetes
  20. 1760
    “…Average costs over the entire period were $2,720 per week for the targeted treatment group and $3,453 per week for the control group, (P = 0.036). …”
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    Precision oncology in advanced cancer patients improves overall survival with lower weekly healthcare costs
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