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242por Schimpl, Marianne, Zheng, Xiaowei, Borodkin, Vladimir S., Blair, David E., Ferenbach, Andrew T., Schüttelkopf, Alexander W., Navratilova, Iva, Aristotelous, Tonia, Albarbarawi, Osama, Robinson, David A., Macnaughtan, Megan A., van Aalten, Daan M.F.“…Protein O-GlcNAcylation is an essential post-translational modification on hundreds of intracellular proteins in metazoa, catalyzed by O-GlcNAc transferase using unknown mechanisms of transfer and substrate recognition. …”
Publicado 2012
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243por Sirivarasai, Jintana, Wananukul, Winai, Kaojarern, Sming, Chanprasertyothin, Suwannee, Thongmung, Nisakron, Ratanachaiwong, Wipa, Sura, Thanyachai, Sritara, PiyamitEnlace del recurso
Publicado 2013
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244“…Development of Nourseothricin N-acetyl transferase (NAT) as a selection marker for mammalian cells is described. …”
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245Global Analysis of Apicomplexan Protein S-Acyl Transferases Reveals an Enzyme Essential for Invasionpor Frénal, Karine, Tay, Chwen L, Mueller, Christina, Bushell, Ellen S, Jia, Yonggen, Graindorge, Arnault, Billker, Oliver, Rayner, Julian C, Soldati-Favre, Dominique“…However, nothing is known so far about the repertoire of protein S-acyl transferases (PATs) that catalyse this modification in Apicomplexa. …”
Publicado 2013
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247“…P-glycoprotein (P-gp) and glutathione S-transferase π (GST-π) are not only drug-resistance markers, but also prognostic markers of various cancers. …”
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248por Borodkin, Vladimir S., Schimpl, Marianne, Gundogdu, Mehmet, Rafie, Karim, Dorfmueller, Helge C., Robinson, David A., vanAalten, Daan M. F.“…Inhibitors of OGT (O-GlcNAc transferase) are valuable tools to study the cell biology of protein O-GlcNAcylation. …”
Publicado 2014
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249por Leonel, Camila, Gelaleti, Gabriela B, Jardim, Bruna V, Moschetta, Marina G, Regiani, Vitor R, Oliveira, Juliana G, Zuccari, Debora APC“…BACKGROUND: Glutathione (GSH) is one of the most important agents of the antioxidant defense system of the cell because, in conjunction with the enzymes glutathione peroxidase (GSH-Px) and glutathione S transferase pi (GSTpi), it plays a central role in the detoxification and biotransformation of chemotherapeutic drugs. …”
Publicado 2014
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250por Odebrecht Vargas Nunes, Sandra, Pizzo de Castro, Márcia Regina, Ehara Watanabe, Maria Angelica, Losi Guembarovski, Roberta, Odebrecht Vargas, Heber, Vissoci Reiche, Edna Maria, Kaminami Morimoto, Helena, Dodd, Seetal, Berk, Michael“…Laboratory assessment included glutathione-S-transferases M1 (GSTM1) and T1 (GSTT1), which were detected by a multiplex-PCR protocol. …”
Publicado 2014
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251por Mao, Yu, Qi, Xiaolong, Xu, Wenjun, Song, Haoming, Xu, Mingxin, Ma, Wanrong, Zhou, Lin“…BACKGROUND: Atherosclerosis is a chronic inflammatory process, in which oxidative stress is the key event. Gamma-glutamyl transferase (GGT) is a cellular production of oxidants. …”
Publicado 2014
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252“…The glutathione transferase (GST) superfamily plays key roles in the detoxification of various xenobiotics. …”
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253“…Glutathione transferases (GST) were purified from locally isolated bacteria, Acinetobacter calcoaceticus Y1, by glutathione-affinity chromatography and anion exchange, and their substrate specificities were investigated. …”
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254“…OBJECTIVE(S): Glaucoma is the second leading cause of blindness and it is related to oxidative stress based on numerous studies. Glutathione S-transferases (GSTs) are members of multigenic family, which have important role in cells as an antioxidant. …”
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255por Huygen, Kris“…The Ag85 complex is a 30–32 kDa family of three proteins (Ag85A, Ag85B, and Ag85C), which all three possess enzymatic mycolyl-transferase activity involved in the coupling of mycolic acids to the arabinogalactan of the cell wall and in the biogenesis of cord factor. …”
Publicado 2014
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256“…BACKGROUND/AIMS: Glutathione S-transferases (GSTs) are cytosolic enzymes excreted from renal tubules following tubular damage. α-GST primarily originates from proximal tubules, while π-GST from distal tubules and collecting ducts. …”
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257por de Oliveira, Diêgo Madureira, de Farias, Marcel Tavares, Teles, André Lacerda Braga, dos Santos Junior, Manoelito Coelho, de Cerqueira, Martins Dias, Lima, Rute Maria Ferreira, El-Bachá, Ramon Santos“…The enzyme glutathione S-transferases (GST) detoxify electrophilic xenobiotics and endogenous secondary metabolites formed during oxidative stress. …”
Publicado 2014
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258“…Glutathione transferases (GST) are an ancient superfamily comprising a large number of paralogous proteins in a single organism. …”
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259por Pégeot, Henri, Koh, Cha San, Petre, Benjamin, Mathiot, Sandrine, Duplessis, Sébastien, Hecker, Arnaud, Didierjean, Claude, Rouhier, Nicolas“…Glutathione transferases (GSTs) constitute a superfamily of enzymes with essential roles in cellular detoxification and secondary metabolism in plants as in other organisms. …”
Publicado 2014
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