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281por Oyamada, Masahito, Dempo, Kimimaro, Fujimoto, Yoshinori, Takahashi, Hidetoshi, Satosh, Mutsumi I., Mori, Michio, Masuda, Ryuichi, Yoshida, Michihiro C., Satosh, Kimihiko, Sato, Kiyomi“…Spontaneous occurrence of placental glutathione S‐transferase (GST‐P)‐positive foci was observed in the livers of 5‐month‐old LEC rats. …”
Publicado 1988
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282“…In addition, As stimulates the generation of free radicals and reactive oxygen species (ROS), resulting in oxidative stress. Glutathione S-transferases (GSTs) quench reactive molecules with the addition of glutathione (GSH) and protect the cell from oxidative damage. …”
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283por Rafie, Karim, Gorelik, Andrii, Trapannone, Riccardo, Borodkin, Vladimir S., van Aalten, Daan M. F.“…[Image: see text] O-GlcNAc transferase (OGT) is an essential glycosyltransferase that installs the O-GlcNAc post-translational modification on the nucleocytoplasmic proteome. …”
Publicado 2018
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284por Hernandez, Emmanuel Pacia, Kusakisako, Kodai, Talactac, Melbourne Rio, Galay, Remil Linggatong, Hatta, Takeshi, Fujisaki, Kozo, Tsuji, Naotoshi, Tanaka, Tetsuya“…Presently, the major method of control for this tick is the use of chemical acaricides. The glutathione S-transferase (GST) system is one mechanism through which the tick metabolizes these acaricides. …”
Publicado 2018
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285por Sharma, Rohit, Terrão, Monica Cristina, Castro, Felipe Freitas, Breitling, Reinhard, Faça, Vitor, Oliveira, Eduardo Brandt, Cruz, Angela Kaysel“…Leucyl, phenylalanyl-tRNA protein transferase and arginyl-tRNA protein transferase are key components of this pathway in E. coli and eukaryotes, respectively. …”
Publicado 2018
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286por Bertini, Simone, Saccomanni, Giuseppe, Del Carlo, Sara, Digiacomo, Maria, Gargini, Claudia, Piano, Ilaria, Campisi, Giuseppe Matteo, Ghidoni, Riccardo, Macchia, Marco, Manera, Clementina“…In this work, we reported the application and validation of an improved high-performance liquid chromatography method coupled with a fluorimetric detector (HPLC-FL) to screen the activity of two heterocyclic derivatives reported as serine palmitoyl transferase (SPT) inhibitors. The analytical conditions were optimized in terms of the derivatization procedure, chromatographic condition, extraction procedure, and method validation according to EMEA guidelines. …”
Publicado 2017
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287por Rodrigues-Fleming, Gabriela Helena, Fernandes, Glaucia Maria de Mendonça, Russo, Anelise, Biselli-Chicote, Patrícia Matos, Netinho, João Gomes, Pavarino, Érika Cristina, Goloni-Bertollo, Eny Maria“…AIM: To evaluate the association between polymorphisms in glutathione S transferases (GSTs) and the risk of sporadic colorectal cancer (SCRC), tumor progression and the survival of patients. …”
Publicado 2018
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288por Wei, Zhen, Song, Jinglue, Wang, Guanghui, Cui, Ximao, Zheng, Jun, Tang, Yunlan, Chen, Xinyuan, Li, Jixi, Cui, Long, Liu, Chen-Ying, Yu, WeiEnlace del recurso
Publicado 2018
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289“…Piperlongumine (PL) is an anticancer compound whose activity is related to the inhibition of human glutathione transferase of pi class (GSTP1) overexpressed in cancerous tumors and implicated in the metabolism of electrophilic compounds. …”
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290“…Tea (Camellia sinensis L.) contains abundant secondary metabolites, which are regulated by numerous enzymes. Hydroxycinnamoyl transferase (HCT) is involved in the biosynthesis pathways of polyphenols and flavonoids, and it can catalyze the transfer of hydroxyconnamoyl coenzyme A to substrates such as quinate, flavanol glycoside, or anthocyanins, thus resulting in the production of chlorogenic acid or acylated flavonol glycoside. …”
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291por Robert-Hazotte, Aline, Faure, Philippe, Neiers, Fabrice, Potin, Catherine, Artur, Yves, Coureaud, Gérard, Heydel, Jean-Marie“…Indeed and second, both the presence and activity of glutathione transferases were evidenced in the nasal mucus of neonates using proteomic and HPLC analysis respectively. …”
Publicado 2019
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293por Barkovskaya, Anna, Seip, Kotryna, Hilmarsdottir, Bylgja, Maelandsmo, Gunhild M., Moestue, Siver A., Itkonen, Harri M.“…In breast cancer, expression of the enzyme that catalyzes O-GlcNAcylation – O-GlcNAc-transferase (OGT), and the extent of protein O-GlcNAcylation, are upregulated in tumor tissue, and correlate with cancer progression. …”
Publicado 2019
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294por Smith, Gaynor A., Lin, Tzu-Huai, Sheehan, Amy E., Van der Goes van Naters, Wynand, Neukomm, Lukas J., Graves, Hillary K., Bis-Brewer, Dana M., Züchner, Stephan, Freeman, Marc R.“…Here, we show that the Drosophila glutathione S-transferase (GST) Gfzf prevents mitochondrial hyperfusion in axons. …”
Publicado 2019
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295“…Although glutathione (GSH) and GSH-dependent enzymes, such as glutathione transferases (GSTs), are thought to have been developed by cyanobacteria to cope with the reactive oxygen species (ROS) that they massively produced by their active photosynthesis, there had been no in vivo analysis of the role of GSTs in cyanobacteria so far. …”
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296por Moghazy, Thanaa Fathy, Elattar, Hoda Aly, Eldeeb, Mona Kamal, Rashad, Radwa Mohammed, Farouk, Ayman Mohamed, Farrag, Assmaa Mostafa“…Conclusion: Glutathione-S-Transferase P1 Promotor methylation plays a role in breast cancer development.…”
Publicado 2019
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297“…High concentration of alpha-glutathione S-transferase (α-GST) in the liver and its short half-life make this enzyme clinically useful in assessing hepatocellular damage. …”
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298“…A frequently cited family of methods employs phosphopantetheinyl transferases (PPTases) to attach probes, provided as conjugates of Coenzyme A. …”
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299por Barnes, Jarrod W., Tian, Liping, Krick, Stefanie, Helton, E. Scott, Denson, Rebecca S., Comhair, Suzy A. A., Dweik, Raed A.“…The serine/threonine hydroxyl-linked N-Acetylglucosamine (O-GlcNAc) transferase (OGT) has been shown to drive pulmonary arterial smooth muscle cell (PASMC) proliferation in IPAH. …”
Publicado 2019
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300por Lacombe, Amanda Meneses Ferreira, Soares, Iberê Cauduro, Mariani, Beatriz Marinho de Paula, Nishi, Mirian Yumie, Bezerra-Neto, João Evangelista, Charchar, Helaine da Silva, Brondani, Vania Balderrama, Tanno, Fabio, Srougi, Victor, Chambo, José Luiz, Costa de Freitas, Ricardo Miguel, Mendonca, Berenice Bilharinho, Hoff, Ana O., Almeida, Madson Q., Weigand, Isabel, Kroiss, Matthias, Zerbini, Maria Claudia Nogueira, Fragoso, Maria Candida Barisson Villares“…Therefore, the discovery of new prognostic biomarkers is of enormous interest. Sterol-O-acyl transferase 1 (SOAT1) is involved in cholesterol esterification and lipid droplet formation. …”
Publicado 2020
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