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341por Yin, Jianxing, Wang, Xiefeng, Ge, Xin, Ding, Fangshu, Shi, Zhumei, Ge, Zehe, Huang, Guang, Zhao, Ningwei, Chen, Dongyin, Zhang, Junxia, Agnihotri, Sameer, Cao, Yuandong, Ji, Jing, Lin, Fan, Wang, Qianghu, Zhou, Qigang, Wang, Xiuxing, You, Yongping, Lu, Zhimin, Qian, Xu“…This conversion is catalyzed by hypoxanthine phosphoribosyl transferase 1 (HPRT1), which is highly expressed in human GBMs. …”
Publicado 2023
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342“…[Image: see text] Terminal deoxynucleotidyl transferase (TdT) is an unusual DNA polymerase that adds untemplated dNTPs to 3′-ends of DNA. …”
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343por Otto, Helge, Reche, Pedro A, Bazan, Fernando, Dittmar, Katharina, Haag, Friedrich, Koch-Nolte, Friedrich“…BACKGROUND: ADP-ribosylation is an enzyme-catalyzed posttranslational protein modification in which mono(ADP-ribosyl)transferases (mARTs) and poly(ADP-ribosyl)transferases (pARTs) transfer the ADP-ribose moiety from NAD onto specific amino acid side chains and/or ADP-ribose units on target proteins. …”
Publicado 2005
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344“…When male guinea pigs were given a single dose of Cd (2.0 mg Cd2+/kg, ip) 72 hr prior to sacrifice, the hepatic reduced glutathione (GSH) level did not change although glutathione S-transferase (GST) activities toward the substrates 1-chloro-2,4-dinitrobenzene (CDNB), 1,2-dichloro-4-nitrobenzene (DCNB), ethacrynic acid (EAA), and 1,2-epoxy-3-(p-nitrophenoxy) propane (ENPP) increased significantly as compared to controls. …”
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345por Randall, B. J., Angus, B., Akiba, R., Hall, A., Cattan, A. R., Proctor, S. J., Jones, R. A., Horne, C. H.“…Using an indirect immunohistochemical technique on paraffin sections, employing a polyclonal antibody to the acidic (placental) form of glutathione-S-transferase (GST), we have evaluated cytoplasmic and nuclear staining in a series of 67 cervical biopsies including normal non neoplastic tissue, immature squamous metaplasia, all grades of cervical intraepithelial neoplasia (CIN) and invasive carcinomas of keratinising and non-keratinising types. …”
Publicado 1990
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346“…Drug resistance in haemopoietic cells may be partly related to the expression of the glutathione-s-transferase (GST) pi and mdr-1 genes. We have used RNA slot blotting techniques to investigate the expression of GST pi in peripheral blood and bone marrow of eleven normal subjects, nine patients with myelodysplastic syndrome (MDS), eighteen patients with acute myeloblastic leukaemia (AML), and thirty-two patients with chronic lymphocyte leukaemia (CLL). …”
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347por Skoog, L., Ost, A., Biberfeld, P., Christensson, B., Hast, R., Lagerlöf, B., Nordenskjöld, B., Reizenstein, P.“…A retrospective study was undertaken to evaluate terminal transferase activity and glucocorticoid receptor content as predictors of prognosis in 52 adult patients with acute myeloid leukemia (AML). …”
Publicado 1984
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348“…The characteristics of a single-cell immunofluorescence assay for terminal deoxynucleotidyl transferase (terminal transferase, TdT) is described. …”
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350por Fernández-Hernando, Carlos, Fukata, Masaki, Bernatchez, Pascal N., Fukata, Yuko, Lin, Michelle I., Bredt, David S., Sessa, William C.“…Importantly, inhibition of DHHC-21 palmitoyl transferase, but not DHHC-3, in human endothelial cells reduces eNOS palmitoylation, eNOS targeting, and stimulated NO production. …”
Publicado 2006
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351“…BACKGROUND: In contrast to many other organisms, the malarial parasite Plasmodium falciparum possesses only one typical glutathione S-transferase. This enzyme, PfGST, cannot be assigned to any of the known GST classes and represents a most interesting target for antimalarial drug development. …”
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352Publicado 1986“…Protein BA was noted to share a number of chemical and physical properties with a family of cytoplasmic enzymes, the glutathione S-transferases. Comparison of the published amino acid composition of protein BA and glutathione S-transferases showed marked similarities. …”
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353por Shang, Wei, Liu, Wei-Hong, Zhao, Xiu-He, Sun, Qin-Jian, Bi, Jian-Zhong, Chi, Zhao-Fu“…BACKGROUND: Glutathione S-transferases (GSTs) play an important role in metabolizing anti-epileptic drugs (AEDs) in liver. …”
Publicado 2008
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354por Vaillancourt, France, Fahmi, Hassan, Shi, Qin, Lavigne, Patrick, Ranger, Pierre, Fernandes, Julio C, Benderdour, Mohamed“…Glucose uptake was assessed by 2-deoxy-D-[(3)H]-glucose. The role of GSH-S-transferase A4-4 (GSTA4-4) in controlling HNE-induced chondrocyte apoptosis was investigated by chondrocyte transfection with small interfering RNA (siRNA) or with the expression vector of GSTA4-4. …”
Publicado 2008
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355por Voorhees, Rebecca M., Weixlbaumer, Albert, Loakes, David, Kelley, Ann C., Ramakrishnan, V.“…Protein synthesis is catalyzed in the peptidyl transferase center (PTC), located in the large (50S) subunit of the ribosome. …”
Publicado 2009
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356por McGrath, Daniel R, Frydoonfar, Hamid, Hunt, Joshua J, Dunkley, Chris J, Spigelman, Allan D“…They are known to induce carcinogen-metabolizing (phase II) enzymes, including the glutathione S-transferase (GST) family. Other effects in humans are not well documented. …”
Publicado 2010
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357
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358por da Fonseca, Rute R, Johnson, Warren E, O'Brien, Stephen J, Vasconcelos, Vítor, Antunes, Agostinho“…BACKGROUND: Cytosolic glutathione transferases (cGST) are a large group of ubiquitous enzymes involved in detoxification and are well known for their undesired side effects during chemotherapy. …”
Publicado 2010
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359“…In the present study, we cloned and sequenced the entire coding regions of two glutathione S-transferase (GST) genes encoding PxGSTs and PxGSTe from the diamondback moth, Plutella xylostella L. …”
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360por Chi, Yunhua, Cheng, Yansong, Vanitha, Jeevanandam, Kumar, Nadimuthu, Ramamoorthy, Rengasamy, Ramachandran, Srinivasan, Jiang, Shu-Ye“…Glutathione S-transferases (GSTs) exist in various eukaryotes and function in detoxification of xenobiotics and in response to abiotic and biotic stresses. …”
Publicado 2011
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