-
441“…[Image: see text] The untemplated activity of terminal deoxynucleotidyl transferase (TdT) represents its most appealing feature. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
442por Rojek, Joanna, Tucker, Matthew R., Rychłowski, Michał, Nowakowska, Julita, Gutkowska, Małgorzata“…Rab proteins are anchored to membranes via posttranslational addition of two geranylgeranyl moieties by the Rab Geranylgeranyl Transferase enzyme (RGT), which consists of RGTA, RGTB and REP subunits. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
443por Cervoni, Matteo, Lo Sciuto, Alessandra, Bianchini, Chiara, Mancone, Carmine, Imperi, Francesco“…PEtN modification can be due to either endogenous (chromosomally encoded) PEtN transferase(s) (e.g., EptA in P. aeruginosa) or plasmid borne MCR enzymes, commonly found in enterobacteria. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
444por Liu, Yanjun, Moural, Timothy, Koirala B K, Sonu, Hernandez, Jonathan, Shen, Zhongjian, Alyokhin, Andrei, Zhu, Fang“…Arthropod Glutathione S-transferases (GSTs) constitute a large family of multifunctional enzymes that are mainly associated with xenobiotic or stress adaptation. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
445por Zhang, Hongyan, He, Jun, Zhao, Yili, Wu, Qifei, Zou, Tiejun, Sun, Jianhua, Zhu, Haitao, Wang, Xinyang, Sun, Fa, Xing, Junping, Tang, Kaifa“…OBJECTIVE: To investigate the relationship between glutathione S-transferase enzyme (GSTM1, T1, and P1) genetic variants and semen quality in men with idiopathic infertility. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
446“…Peptide bond formation on the ribosome requires that aminoacyl-tRNAs and peptidyl-tRNAs are properly positioned on the A site and the P site of the peptidyl transferase center (PTC) so that nucleophilic attack can occur. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
447“…In vitro ADP-ribosyl transferase activity of exotoxin A protein extract was also explored by monitoring its cytotoxicity on Hep-2 cells using sulforhodamine B cytotoxicity assay. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
448por Pedersen, Tobias Bruun, Nielsen, Mikkel Rank, Kristensen, Sebastian Birkedal, Spedtsberg, Eva Mie Lang, Sørensen, Trine, Petersen, Celine, Muff, Jens, Sondergaard, Teis Esben, Nielsen, Kåre Lehmann, Wimmer, Reinhard, Gardiner, Donald Max, Sørensen, Jens Laurids“…The biosynthetic pathways for the fungal polyketides bikaverin and bostrycoidin, from Fusarium verticillioides and Fusarium solani respectively, were reconstructed and heterologously expressed in S. cerevisiae alongside seven different phosphopantetheinyl transferases (PPTases) from a variety of origins spanning bacterial, yeast and fungal origins. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
449por Zhang, Aiqin, Luo, Rui, Li, Jiawen, Miao, Rongqing, An, Hui, Yan, Xiufeng, Pang, Qiuying“…Glutathione (GSH) conjugation with intermediates is required for the biosynthesis of glucosinolate (GSL) by serving as a sulfur supply. Glutathione-S-transferases (GSTs) primarily work on GSH conjugation, suggesting their involvement in GSL metabolism. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
450por Inaba, Kazue, Ebihara, Kana, Senda, Miki, Yoshino, Ryunosuke, Sakuma, Chisako, Koiwai, Kotaro, Takaya, Daisuke, Watanabe, Chiduru, Watanabe, Akira, Kawashima, Yusuke, Fukuzawa, Kaori, Imamura, Riyo, Kojima, Hirotatsu, Okabe, Takayoshi, Uemura, Nozomi, Kasai, Shinji, Kanuka, Hirotaka, Nishimura, Takashi, Watanabe, Kodai, Inoue, Hideshi, Fujikawa, Yuuta, Honma, Teruki, Hirokawa, Takatsugu, Senda, Toshiya, Niwa, Ryusuke“…RESULTS: Here, we report that several flavonoids, including daidzein, inhibit the activity of glutathione S-transferase Noppera-bo (Nobo), an enzyme used for the biosynthesis of the insect steroid hormone ecdysone, in the yellow fever mosquito Aedes aegypti. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
451por Segura-Aguilar, Juan, Muñoz, Patricia, Inzunza, Jose, Varshney, Mukesh, Nalvarte, Ivan, Mannervik, Bengt“…The explanation of this paradox is the existence of protective tools against aminochrome neurotoxicity composed of the enzymes DT-diaphorase, expressed in these neurons, and glutathione transferase M2-2, expressed in astrocytes. Recently, it has been reported that dopaminergic neurons can be protected by glutathione transferase M2-2 from astrocytes, which secrete exosomes containing the protective enzyme.…”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
452por Zheng, Yanhui, Yan, Weizhu, Dou, Chao, Zhou, Dan, Chen, Yunying, Jin, Ying, Yang, Lulu, Zeng, Xiaotao, Cheng, Wei“…A Mg(2+)‐dependent protein flavin mononucleotide (FMN) transferase (FmnB; UniProt: LMRG_02181) in EET is responsible for the transfer of electrons from intracellular to extracellular by hydrolyzing cofactor flavin adenine dinucleotide (FAD) and transferring FMN. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
453por Duan, Qiang, Li, Guo-Rui, Qu, Yi-Peng, Yin, Dong-Xue, Zhang, Chun-Ling, Chen, Yong-Sheng“…Euphorbiaceae, a family of plants mainly grown in the tropics and subtropics, is also widely distributed all over the world and is well known for being rich in rubber, oil, medicinal materials, starch, wood and other economically important plant products. Glutathione S-transferases (GSTs) constitute a family of proteins encoded by a large supergene family and are widely expressed in animals, bacteria, fungi and plants, but with few reports of them in Euphorbiaceae plants. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
454por Cheng, Bo, Hong, Xiaoliang, Wang, Linfang, Cao, Yuanyuan, Qin, Dengli, Zhou, Han, Gao, Dianshuai“…METHODS: The expression of glutathione S‐transferase A4 (GSTA4) in glioblastoma and the effect of curzerene on the expression of GSTA4 and matrix metalloproteinase 9 and the activation of the mTOR pathway were detected by Western blotting and RT‐PCR, and the effects of curzerene treatment on glioma malignant character were detected by cell biological assays. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
455por Jin, Yi, Tan, Yanjie, Zhao, Pengxiang, Guo, Yu, Chen, Shilin, Wu, Jian, Ren, Zhuqing“…However, unclear molecular mechanism of hepatic steatosis impedes the therapy of this hepatic steatosis. Glutathione-S-transferase mu 2 (GSTM2), as a member of phase II drug metabolizing enzymes (DMEs), regulates cellular antioxidant and detoxificant. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
456por Alroomi, Moudhi, Rajan, Rajesh, Alsaber, Ahmad, Pan, Jiazhu, Abdullah, Mohammed, Abdelnaby, Hassan, Aboelhassan, Wael, AlNasrallah, Noor, Al‐Bader, Bader, Malhas, Haya, Ramadhan, Maryam, Hussein, Soumoud, Alotaibi, Naser, Al Saleh, Mohammad, Zhanna, Kobalava D., Almutairi, Farah“…BACKGROUND: This study investigates in‐hospital mortality amongst patients with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and its relation to serum levels of gamma‐glutamyl transferase (GGT). METHODS: Patients were stratified according to serum levels of gamma‐glutamyl transferase (GGT) (GGT<50 IU/L or GGT≥50 IU/L). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
457Glutathione S-transferase: a candidate gene for berry color in muscadine grapes (Vitis rotundifolia)por Varanasi, Aruna, Worthington, Margaret, Nelson, Lacy, Brown, Autumn, Chizk, Thomas Mason, Threlfall, Renee, Howard, Luke, Conner, Patrick, Figueroa-Balderas, Rosa, Massonnet, Mélanie, Cantu, Dario, Clark, John R“…In this study, we identified glutathione S-transferase4 as a likely candidate gene for anthocyanin transport within the berry color locus. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
458por Fan, Hui-Hui, Li, Bao-Qing, Wu, Ke-Yun, Yan, Hai-Dan, Gu, Meng-Jie, Yao, Xing-Hao, Dong, Hao-Jia, Zhang, Xiong, Zhu, Jian-Hong“…Enzymes including cytochromes P450 (CYPs), esterases and glutathione S-transferases (GSTs) are responsible for the xenobiotic metabolism and may functionally compensate each other for subtypes in the same class. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
459por Tang, Feng, Yang, Chao, Li, Feng-Ping, Yu, Dong-Hu, Pan, Zhi-Yong, Wang, Ze-Fen, Li, Zhi-Qiang“…Emerging evidence has shown that zinc finger Asp-His-His-Cyc-type (ZDHHC) palmitoyl transferases participate in regulating tumor progression and the immune microenvironment. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
460por Gondane, Aishwarya, Poulose, Ninu, Walker, Suzanne, Mills, Ian G, Itkonen, Harri M“…Co-targeting of O-GlcNAc transferase (OGT) and the transcriptional kinase cyclin-dependent kinase 9 (CDK9) is toxic to prostate cancer cells. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto