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481por Aioub, Ahmed A. A., Hashem, Ahmed S., El-Sappah, Ahmed H., El-Harairy, Amged, Abdel-Hady, Amira A. A., Al-Shuraym, Laila A., Sayed, Samy, Huang, Qiulan, Abdel-Wahab, Sarah I. Z.“…Insect glutathione S-transferases (GSTs) serve critical roles in insecticides and other forms of xenobiotic chemical detoxification. …”
Publicado 2023
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482por Dodge, Greg J., Anderson, Alyssa J., He, Yi, Liu, Weijing, Viner, Rosa, Imperiali, Barbara“…Here, we leverage cutting-edge methods to stabilize, purify, and structurally characterize WbaP, a phosphoglycosyl transferase (PGT) from Salmonella enterica (LT2) O-antigen biosynthesis without detergent solubilization from the lipid bilayer. …”
Publicado 2023
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483por Yuce, Ahmet, Keles, Mevlut, Benli, Erdal, Cirakoglu, Abdullah, Yazici, Ibrahim, Nalbant, Ismail“…We aimed to investigate the gamma glutamyl transferase (GGT) levels, a serum biomarker not affected by situations other than cancer causing elevated PSA. …”
Publicado 2023
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484
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485por Kato, Naoki, Ebihara, Kana, Nogawa, Toshihiko, Futamura, Yushi, Inaba, Kazue, Okano, Akiko, Aono, Harumi, Fujikawa, Yuuta, Inoue, Hideshi, Matsuda, Kazuhiko, Osada, Hiroyuki, Niwa, Ryusuke, Takahashi, Shunji“…In addition to these known biological activities, we revealed that the compounds showed inhibitory activity against the insect steroidogenic glutathione S-transferase Noppera-bo. Engineering the decalin configurations would be useful not only to find derivatives with better biological activities but also to discover overlooked biological activities.…”
Publicado 2023
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486
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487por Grussy, Katarzyna, Łaska, Magdalena, Moczurad, Wiktoria, Król-Kulikowska, Magdalena, Ściskalska, Milena“…Glutathione S-transferases are a family of enzymes, whose main role is to detoxify cells from many exogenous factors, such as xenobiotics or carcinogens. …”
Publicado 2023
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488
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489por Ketterer, B, Harris, J M, Talaska, G, Meyer, D J, Pemble, S E, Taylor, J B, Lang, N P, Kadlubar, F F“…Cytosolic glutathione S-transferases (GSTs) are a supergene family of dimeric enzymes capable of detoxifying a number of carcinogenic electrophiles. …”
Publicado 1992
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490“…With the aid of immunohistochemical methods the localization of the various isoenzymes of glutathione S-transferase was investigated. The alpha isoenzyme was present solely in the proximal tubular cells of the human kidney, while the pi form was restricted to the distal convoluted tubules, the thin loop of Henle, and the collecting ducts. …”
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491por Imboden, Medea, Downs, Sara H, Senn, Oliver, Matyas, Gabor, Brändli, Otto, Russi, Erich W, Schindler, Christian, Ackermann-Liebrich, Ursula, Berger, Wolfgang, Probst-Hensch, Nicole M“…Deficiency in antioxidative and detoxifying Glutathione S-transferase (GST) gene has been associated with poorer lung function in children, smokers and patients with respiratory diseases. …”
Publicado 2007
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492“…The aim of the present study was to analyse in invasive carcinomas of the uterine cervix, the anionic glutathione S transferase (GST pi) gene, possibly implicated in the drug resistance of human cancers. …”
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493“…Optimized methods for extraction and enzyme assay in crude tissue preparations were used to determine the amounts of terminal deoxnucleotidyl transferase (TdT) in malignant lymphomas. The TdT concentration was increased only in lymphoblastic lymphomas (LL) and was as high in these tumours as in the white blood cells from untreated patients with acute lymphoblastic leukaemia (ALL). …”
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494
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495Publicado 1987“…Studies using deletion mutagenesis indicate that a processing recognition site lies proximal to the normal cleavage position between gln32 and ser33 of pre-ornithine carbamyl transferase (pOCT). pOCT cDNA was manipulated to delete codons specifying amino acids 22-30 of the signal sequence. …”
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496
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497“…Here, experiments in vivo and in vitro demonstrate that Akr1p, a polytopic membrane protein containing a DHHC cysteine-rich domain (CRD), is a palmitoyl transferase (PTase). In vivo, we find that the casein kinase Yck2p is palmitoylated and that Akr1p function is required for this modification. …”
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498
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499por Li, Yu-Fen, Gauderman, W. James, Conti, David V., Lin, Pi-Chu, Avol, Edward, Gilliland, Frank D.“…BACKGROUND: Glutathione S-transferase P1 (GSTP1) plays a role in a spectrum of respiratory diseases; however, the effects of sequence variation across the entire locus in asthma pathogenesis have yet to be determined. …”
Publicado 2008
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500por Zheng, T, Holford, T R, Zahm, S H, Owens, P H, Boyle, P, Zhang, Y, Zhang, B, Wise, J P, Stephenson, L P, Ali-Osman, F“…Recent studies suggest that genetic polymorphisms of glutathione S-transferases (GSTs) may modify this relation. To determine if breast cancer risk is associated with GSTM1 and GSTT1 genetic polymorphisms, and to evaluate the effect modification between GST genotypes and alcohol consumption in the risk of breast cancer, we conducted a case–control study in the state of Connecticut in the period 1998 and 2001. …”
Publicado 2003
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