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10201por Lu, Juan, An, Jianhong, Wang, Jiawei, Cao, Xiaowen, Cao, Yuqing, Huang, Chengjie, Jiao, Shiming, Yan, Dongsheng, Lin, Xinhua, Zhou, Xiangtian“…Immunofluorescence staining were performed to assess proteins distribution and terminal deoxynucleotidyl transferase dUTP nick-end labeling staining were used for determining apoptosis. …”
Publicado 2022
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10202por Jo, Sung-Hyun, Park, Han-Gyu, Song, Won-Suk, Kim, Seong-Min, Kim, Eun-Jung, Yang, Yung-Hun, Kim, Jae-Seok, Kim, Byung-Gee, Kim, Yun-Gon“…To confirm the role of PEA in CAMP resistance of EcN, minimum inhibitory concentrations (MICs) of polymyxin B and colistin were determined using a wild-type strain and a mutant strain with deletion of eptA gene encoding PEA transferase. Our results confirmed that MICs of polymyxin B and colistin for the wild-type were twice as high as those for the mutant. …”
Publicado 2019
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10203“…The findings illustrated that IL2RB contents were remarkably linked to tumor immune invasion, tumor microenvironment, TMB, MSI, DNA repair genes, methyl transferases, immune modulatory factors, and immune or molecular subtypes in pan-cancer. …”
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10204por Xu, Duling, Li, Hongyan, Katsube, Takanori, Huang, Guomin, Liu, Jiadi, Wang, Bing, Zhang, Hong“…Analysis of 8-hydroxy-2 deoxyguanosine (8-OHdG), a biomarker of oxidative DNA damage, was performed with immunofluorescence, and terminal deoxynucleotidyl transferase-mediated nick end labeling assays were used to detect apoptotic cells. …”
Publicado 2022
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10205por Li, Chuanshun, Zhao, Yaoyao, Qi, Yuting, Duan, Chonghao, Zhang, Hengyang, Zhang, Quan“…In addition, the transgenic wheat plants displayed significantly higher peroxidase (POD) and glutathione S-transferase (GST) activity, as well as markedly lower malondialdehyde (MDA) content than that of the WT during salt stress conditions. …”
Publicado 2022
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10206por Cawley, Niamh X., Lyons, Anna T., Abebe, Daniel, Luke, Rachel, Yerger, Julia, Telese, Rebecca, Wassif, Christopher A., Bailey-Wilson, Joan E., Porter, Forbes D.“…To test the importance of complex asparagine-linked glycosylation in NPC1 pathology, we generated NPC1 knock-out mice deficient in MGAT5, a key Golgi-resident glycosyl transferase involved in complex asparagine-linked glycosylation. …”
Publicado 2022
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10207por Rehman, Rukhshanda, Sial, Nuzhat, Ismail, Amina, Hussain, Shabir, Abid, Sobia, Javed, Maryium, Nadeem, Khansa, Ayoub, Muhammad“…The concentrations of serum urea, glutamyl transferase (GGT), and triglycerides (TG) were lower in untreated (T0) and treated groups (T1, T2, T3, and T4). …”
Publicado 2022
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10208por Martinez-Sanchez, Luisa, Cobbaert, Christa M., Noordam, Raymond, Brouwer, Nannette, Blanco-Grau, Albert, Villena-Ortiz, Yolanda, Thelen, Marc, Ferrer-Costa, Roser, Casis, Ernesto, Rodríguez-Frias, Francisco, den Elzen, Wendy P. J.“…The upper limits of Gamma-glutamyl transferase were markedly higher in the Dutch study compared to Vall d’Hebron results. …”
Publicado 2022
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10209“…In this study, we explored the inhibition potential of compounds from Cucurbita maxima using molecular docking studies on Schistosoma mansoni purine nucleoside phosphorylase (SmPNP) and Schistosoma haematobium 28-kDa glutathione S-transferase (Sh28kDaGST). Following molecular docking studies and analysis of the active sites, the primary amino acids that were observed and shown to be involved in the SmPNP-ligand interaction are CYS 33, ARG 86, HIS 88, TYR 90, ALA 118, ALA 119, PRO 200, TYR 202, GLU 203, VAL 219, MET 221, THR 244, ASN 245, PRO 257 and HIS 259. …”
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10210por Mansour, Abdallah Tageldein, Alsaqufi, Ahmed Saud, Omar, Eglal Ali, El-Beltagi, Hossam S., Srour, Tarek Mohamed, Yousef, Mokhtar Ibrahim“…In addition, glutathione reduced contents, glutathione S-transferases, glutathione peroxidase, catalase, and superoxide dismutase activities significantly increased with different dietary supplementation in a dose-dependent manner. …”
Publicado 2022
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10211por Li, Xiaoting, Huang, Hantang, Rizwan, Hafiz Muhammad, Wang, Naiyu, Jiang, Jingyi, She, Wenqin, Zheng, Guohua, Pan, Heli, Guo, Zhixiong, Pan, Dongming, Pan, Tengfei“…Among these DEGs, PAL (phenylalanine ammonia lyase), HCT (hydroxycinnamoyl-CoA shikimate/quinate hydroxycinnamoyl transferase), 4CL2 (4-coumarate: CoA ligase), C4H (cinnamate 4-hydroxylase), C3′H (p-coumarate 3-hydroxylase), and CCoAOMT1 (caffeoyl CoA 3-Omethyltransferase) were the most distinct DEGs in granulated juice sacs. …”
Publicado 2022
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10212por Attar, Roba, Alatawi, Eid A., Aba Alkhayl, Faris F., Alharbi, Khloud Nawaf, Allemailem, Khaled S., Almatroudi, Ahmad“…Two vaccine candidates were evaluated for epitope prediction including the superoxide dismutase and gamma-glutamyl transferase protein. The epitope prediction phase involved the prediction of a variety of B-Cell and T-cell epitopes, and the epitopes that met certain criteria, such as antigenicity, immunogenicity, non-allergenicity, and non-toxicity were chosen. …”
Publicado 2022
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10213por Tian, Gang, Liu, Chuanjie, Gong, Qi, Yu, Zhiping, Wang, Haitao, Zhang, Daoqiang, Cong, Haibo“…The necrosis and apoptosis of the femoral head was evaluated by histological and Terminal-deoxynucleoitidyl Transferase Mediated Nick End Labeling (TUNEL) assay. …”
Publicado 2021
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10214por Maleita, Carla, Esteves, Ivânia, Braga, Mara E. M., Figueiredo, Joana, Gaspar, Marisa C., Abrantes, Isabel, de Sousa, Hermínio C.“…Moreover, the potential mode of action of JUG/1,4-NTQ was investigated for the first time on RKN, through the assessment of reactive oxygen species (ROS) generation, acetylcholinesterase (AChE) in vitro inhibitory activity and expression analysis of ache and glutathione-S-transferase (gst) genes. 1,4-NTQ was the most active compound, causing ≥50% J2 mortality at 250 ppm, within 24 h. …”
Publicado 2022
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10215“…Western blot analysis, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) staining, Immunohistochemistry (IHC), and flow cytometry were carried out in every experimental group. …”
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10216por Abobaker, Halima, Omer, Nagmeldin A., Hu, Yun, Idriss, Abdulrahman A., Zhao, Ruqian“…Betaine significantly (P < 0.05) increased adrenal expression of genes involved in one-carbon metabolism and DNA methylation, such as S-adenosyl homocysteine hydrolase, betaine-homocysteine-methyltransferase, methionine adenosyl transferase and DNA methyltransferases, yet the promoter regions of most steroidogenic genes were significantly (P < 0.05) hypomethylated. …”
Publicado 2022
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10217“…Molecular analyses including loss-of-function and ChIP assays demonstrated a role for the concerted action of the transcription factor YY1 and the arginine methyl transferase PRMT5 in restricting the expression of Itch gene by conferring repressive symmetrical H4R3me2 marks on its promoter. …”
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10218“…Our objective was to estimate the contributions of C-reactive protein (CRP), gamma glutamyl transferase (GGT), and micronutrient antioxidants (bilirubin, carotenoids, uric acid, vitamins A, C–E?) …”
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10219por He, Ting, Xu, Tongshuo, Muhae-Ud-Din, Ghulam, Guo, Qingyun, Liu, Taiguo, Chen, Wanquan, Gao, Li“…On the basis of gene ontology, the upregulated proteins were linked with metabolic process, catalytic activity, transferase activity, photosynthetic membrane, extracellular region and oxidoreductase activity. …”
Publicado 2022
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10220por Wang, Yanwu, Shen, Ning, Spurlin, Gervase, Korm, Sovannarith, Huang, Sarah, Anderson, Nicole M., Huiting, Leah N., Liu, Hudan, Feng, Hui“…Metabolomics flux analysis of T-ALL reveals enhanced reductive carboxylation upon genetic depletion of the E2 subunit of KGDHC, dihydrolipoamide-succinyl transferase (DLST), mimicking pharmacological inhibition of the complex. …”
Publicado 2022
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