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1021por Bhattacharjee, Pritha, Paul, Somnath, Banerjee, Mayukh, Patra, Deblina, Banerjee, Priyam, Ghoshal, Nanda, Bandyopadhyay, Arun, Giri, Ashok K.“…The gene for glutathione-S-transferase (GST) M1 (GSTM1), a member of the GST-superfamily, is widely studied in cancer risk with regard to the homozygous deletion of the gene (GSTM1 null), leading to a lack of corresponding enzymatic activity. …”
Publicado 2013
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1022“…S-acylation of eukaryotic proteins is the reversible attachment of palmitic or stearic acid to cysteine residues, catalysed by protein S-acyl transferases that share an Asp-His-His-Cys (DHHC) motif. …”
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1023por Shafqat, Naeem, Kavanagh, Kate L., Sass, Jörn Oliver, Christensen, Ernst, Fukao, Toshiyuki, Lee, Wen Hwa, Oppermann, Udo, Yue, Wyatt W.“…Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency is a rare inherited metabolic disorder of ketone metabolism, characterized by ketoacidotic episodes and often permanent ketosis. …”
Publicado 2013
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1024“…BACKGROUND: Human papillomavirus (HPV) infection is considered the major cause of cervical cancer (CC), but a number of infected women do not develop invasive lesions, suggesting the role of genetic susceptibility and environmental co-factors for cancer outbreak. Glutathione S- transferases (GSTs) are multifunctional enzymes that play a key role in the detoxification of varieties of both endogenous products of oxidative stress and exogenous carcinogens. …”
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1025por López-Fernández, Loida, Ruiz-Roldán, Carmen, Pareja-Jaime, Yolanda, Prieto, Alicia, Khraiwesh, Husam, Roncero, M. Isabel G.“…In silico analysis revealed the existence of seven putative N-glycosyl transferase encoding genes (named gnt) in F. oxysporum f.sp. lycopersici genome. gnt2 deletion mutants showed a dramatic reduction in virulence on both plant and animal hosts. …”
Publicado 2013
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1026por Martins, José Carlos, Campos, Alexandre, Osório, Hugo, da Fonseca, Rute, Vasconcelos, Vítor“…This fact highlights the potential role of detoxification enzymes, such as glutathione transferases (GSTs), in this bivalve resistance. Nevertheless, the GST system has not been extensively described in these organisms. …”
Publicado 2014
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1027“…Glutathione S-transferases (GSTs) are multifunctional proteins encoded by large gene family in plants, which play important role in cellular detoxification of several endobiotic and xenobiotic compounds. …”
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1028por Bourke, Claire D., Nausch, Norman, Rujeni, Nadine, Appleby, Laura J., Trottein, François, Midzi, Nicholas, Mduluza, Takafira, Mutapi, Francisca“…An anti-schistosome vaccine based on Schistosoma haematobium glutathione-S-transferase (GST) is currently in Phase III clinical trials, but little is known about the immune responses directed against this antigen in humans naturally exposed to schistosomes or how these responses change following PZQ treatment. …”
Publicado 2014
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1029por Dey, Tapan, Gogoi, Kabita, Unni, Bala Gopalan, Kalita, Munmi, Bharadwaz, Moonmee, Bhattacharjee, Minakshi, Boruah, Pranab Kumar, Bora, Thaneswar, Ozah, Dibyajyoti, Kalita, ManojEnlace del recurso
Publicado 2014
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1030por Chen, Xu, Makarewicz, Jacek M., Knauf, Jeffrey A., Johnson, Linda K., Fagin, James A.“…These data suggest that farnesyl transferase inhibitors should be reevaluated as targeted agents for human HRAS-driven cancers, such as those of bladder, thyroid and other epithelial lineages.…”
Publicado 2013
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1031“…O-GlcNAc Transferase (OGT) catalyzes protein O-GlcNAcylation, an abundant and dynamic nuclear and cytosolic modification linked to epigenetic regulation of gene expression. …”
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1032“…The S-layer proteins as well as other surface-exposed proteins are modified via N-glycosylation, in which the oligosaccharyl transferase AglB catalyzes the final step of the transfer of the glycan tree to the nascent protein. …”
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1033por Afrand, Mohammadhosain, Khalilzadeh, Saeedhossein, Bashardoost, Nasrollah, Sheikhha, Mohammad Hasan“…The aim of this study was to assess the possible association between genetic polymorphisms of the glutathione S-transferase-Theta (GSTT1) and the risk of the development of DM in Zoroastrian females in Yazd, Iran. …”
Publicado 2015
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1034por Xie, Yue, Zhou, Xuan, Chen, Lin, Zhang, Zhihe, Wang, Chengdong, Gu, Xiaobin, Wang, Tao, Peng, Xuerong, Yang, Guangyou“…BACKGROUND: Baylisascaris schroederi, an intestinal nematode of the giant panda, is the cause of the often fatal disease, baylisascariasis. Glutathione S-transferases (GSTs) are versatile enzymes that can affect parasite survival and parasite-host interactions and, are therefore, potential targets for the development of diagnostic tests and vaccines. …”
Publicado 2015
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1035“…To study the effects of glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) polymorphisms on age-related cataract (ARC). …”
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1036“…Albuminuria and elevated gamma-glutamyl transferase increased the risk of hypertension (adjusted hazard ratio 1.4–1.7) in this population. …”
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1038por Sawers, L, Ferguson, M J, Ihrig, B R, Young, H C, Chakravarty, P, Wolf, C R, Smith, G“…Platinum drugs are metabolised by glutathione S-transferase P1 (GSTP1), which is abundantly, but variably expressed in ovarian tumours. …”
Publicado 2014
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1039por de Abreu, Francine B., Gallagher, Torrey L., Liu, Emmeline Z., Tsongalis, Gregory J.Enlace del recurso
Publicado 2014
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1040por AFRAND, Mohammadhosain, BASHARDOOST, Nasrollah, SHEIKHHA, Mohammad Hasan, AFKHAMI-ARDEKANI, Mohammad“…BACKGROUND: The aim of this study was to assess the possible association between genetic polymorphisms of the glutathione S-transferase (GST) gene family and the risk of the development of metabolic syndrome (MS) in Zoroastrian females in Yazd, Iran. …”
Publicado 2015
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