-
10481por Hegazy, Ahmed Medhat, Farid, Ayman Samir, Hafez, Ahmed S., Eid, Rania M., Nasr, Soad M.“…RESULTS: CNC improved MCDD-induced liver dysfunctions by recovering serum alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase activities to their normal levels. The glutathione (GSH) level and superoxide dismutase (SOD) activity significantly decreased, while lipid peroxidation (as reflected by malondialdehyde [MDA]) markedly increased in the liver tissue of the MCDD group. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10482por Kiiskinen, Tuomo, Mars, Nina J., Palviainen, Teemu, Koskela, Jukka, Rämö, Joel T., Ripatti, Pietari, Ruotsalainen, Sanni, Palotie, Aarno, Madden, Pamela A. F., Rose, Richard J., Kaprio, Jaakko, Salomaa, Veikko, Mäkelä, Pia, Havulinna, Aki S., Ripatti, Samuli“…When adjusted for self-reported alcohol consumption, education, marital status, and gamma-glutamyl transferase blood levels in 28,639 participants with comprehensive baseline data from prospective cohorts, the risk estimate between the highest and lowest quintiles of the PRS was 1.58 (CI = 1.26–1.99, p = 8.2 × 10(–5)). …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10483por Zheng, Wei, Li, Hui, Zhang, Hui, Zhang, Chao, Zhu, Zhonglin, Liang, Hong, Zhou, Yifeng“…Additionally, O-GlcNAcylation transferase (OGT) was the downstream target of miR-7-5p. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10484por Gericke, Oliver, Hansen, Nikolaj Lervad, Pedersen, Gustav Blichfeldt, Kjaerulff, Louise, Luo, Dan, Staerk, Dan, Møller, Birger Lindberg, Pateraki, Irini, Heskes, Allison Maree“…Subsequently, cis-prenyl transferases (CPTs) capable of making NNPP were identified in each species. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10485Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Studypor Kamath, Binita M., Ye, Wen, Goodrich, Nathan P., Loomes, Kathleen M., Romero, Rene, Heubi, James E., Leung, Daniel H., Spinner, Nancy B., Piccoli, David A., Alonso, Estella M., Guthery, Stephen L., Karpen, Saul J., Mack, Cara L., Molleston, Jean P., Murray, Karen F., Rosenthal, Philip, Squires, James E., Teckman, Jeffrey, Wang, Kasper S., Thompson, Richard, Magee, John C., Sokol, Ronald J.“…The median gamma glutamyl transferase also dropped from 612 to 268 in the same age groups. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10486por Ishii, Takamasa, Sasaki, Yosuke, Maeda, Tadashi, Komatsu, Fumiya, Suzuki, Takeshi, Urita, Yoshihisa“…Logistic regression revealed that EBV-IM was predicted by younger age, short onset-to-visit interval, lymphadenopathy, tonsillar white coat, hepatosplenomegaly, atypical lymphocytosis, and elevations of lactate dehydrogenase and gamma-glutamyl transferase. All regression models had areas under the curve of >0.9. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10487“…CMAE at doses of 125 and 250 mg/kg decreased in serum proteins and the activity of aspartate amino transferase, and increased the activity of catalase. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10488por Yang, Shunying, Hao, Dongli, Jin, Man, Li, Yi, Liu, Zengtai, Huang, Yanan, Chen, Tianxiang, Su, Yanhua“…Next, the vigorous induction of glutathione transferase (GST) genes and enzyme activities along with the rise of glutathione (GSH) production suggest the activation of GSH cycling for ROS cleavage. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10489por Hu, Guang-Fu, Wang, Cheng, Hu, Guang-Xia, Wu, Ge, Zhang, Chengjiao, Zhu, Wei, Chen, Cong, Gu, Yutong, Zhang, Hongwei, Yang, Zi’ang“…Apoptotic cell number was detected by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL). …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10490por Turja, Raisa, Sanni, Steinar, Stankevičiūtė, Milda, Butrimavičienė, Laura, Devier, Marie-Hélène, Budzinski, Hélène, Lehtonen, Kari K.“…Biological effects of oil exposure were examined using a battery of biomarkers consisting of enzymes of the antioxidant defense system (ADS), lipid peroxidation, phase II detoxification (glutathione S-transferase), neurotoxicity (acetylcholinesterase inhibition), and geno- and cytotoxicity (micronuclei and other nuclear deformities). …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10491por Jiang, Ya, Bai, Xue, Li, Ting-Ting, AL-Hawwas, Mohammed, Jin, Yuan, Zou, Yu, Hu, Yue, Liu, Lin-Yi, Zhang, Ying, Liu, Qing, Yang, Hao, Ma, Jun, Wang, Ting-Hua, Liu, Jia, Xiong, Liu-Lin“…The HI-induced neurological injury was evaluated by Zea-longa scores, Triphenyte-trazoliumchloride (TTC) staining the Terminal Deoxynucleotidyl Transferased Utp Nick End Labeling (TUNEL) and immunofluorescent staining. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10492por Xiong, Fu, Cao, Yanyan, Guo, Xiaopeng, Zhang, Hongsen, Wang, Jihua, Xiong, Bin, Liang, Bin, Zheng, Chuansheng“…The tumor growth rates, necrosis rates and intrahepatic metastasis were measured, and hematoxylin-eosin (HE), transferase-mediated dUTP-biotin nick end labelling (TUNEL) and Ki67 staining were conducted in each group. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10493“…Using methionyl-tRNA formyl transferase (MTFMT)-deficient cells, which exhibit impaired mitochondrial activity, we examined the role of mitochondrial integrity in regulating innate defense against infection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10494por Yang, Liu, Cao, Huan, Sun, Dong, Hou, Bin, Lin, Ling, Shen, Zhong-Yang, Song, Hong-Li“…Liver function in outflow perfusate was detected by biochemical methods; liver tissue histopathology was observed by hematoxylin–eosin staining; hepatocyte ultrastructure was observed by transmission electron microscopy; hepatocyte apoptosis was detected by terminal deoxynucleotidyl transferase dUTP nick end labeling; liver microcirculation–related indicators were detected by immunofluorescence, immunohistochemistry, Western blotting, and enzyme-linked immunosorbent assay. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10495por Matsui, Hiroshi, Utsumi, Takahiro, Maru, Natsumi, Taniguchi, Yohei, Saito, Tomohito, Hino, Haruaki, Ishida, Mitsuaki, Tsuta, Koji, Murakawa, Tomohiro“…We did not see either keratin-positive thymocytes or terminal deoxynucleotidyl transferase-positive lymphocytes. Furthermore, deviation in the kappa chain and lambda chain-positive plasma cells was not noted. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10496por Liang, Jinhua, Ning, Yongzhong, Dong, Li, Ma, Xiufeng, Li, Shu, Yang, Heran, Li, Qi, Chen, Ling, Gao, Lingjuan, Xu, Yanmin“…Cell viability was assessed by the water-soluble tetrazolium salt (WST-1) assay, and cell apoptosis was assessed by flow cytometry and the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) assay. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10497“…Cell apoptosis was detected using terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. The levels of proteins were measured using Western blot. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10498por Bastug, Aliye, Bodur, Hurrem, Erdogan, Serpil, Gokcinar, Derya, Kazancioglu, Sumeyye, Kosovali, Behiye Deniz, Ozbay, Bahadır Orkun, Gok, Gamze, Turan, Isil Ozkocak, Yilmaz, Gulsen, Gonen, Canan Cam, Yilmaz, Fatma Meric“…ICU patients had lower lymphocytes, percentage of large unstained cell (%LUC), hemoglobin, total protein, and albumin, but higher leucocytes, neutrophils, neutrophil–lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), platelet-lymphocytes ratio (PLR), urea, creatinine, aspartate amino transferase (AST), lactate dehydrogenase (LDH), and D-dimer when compared with non-critically ill patients (p < 0.001). …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10499por Pang, Raymand, Martinello, Kathryn A., Meehan, Christopher, Avdic-Belltheus, Adnan, Lingam, Ingran, Sokolska, Magda, Mutshiya, Tatenda, Bainbridge, Alan, Golay, Xavier, Robertson, Nicola J.“…There was a correlation between Lac/NAA and overall cell death [terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL)] [mean Lac/NAA basal ganglia and thalamus (BGT) voxel r = 0.722, white matter (WM) voxel r = 0.784, p < 0.01] and microglial activation [ionized calcium-binding adapter molecule 1 (Iba1)] (BGT r = −0.786, WM r = −0.632, p < 0.01). …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10500por Zacharia, Anish, Saidemberg, Daniel, Mannully, Chanchal Thomas, Kogan, Natalya M, Shehadeh, Alaa, Sinai, Reut, Zucker, Avigail, Bruck-Haimson, Reut, Goldstein, Nir, Haim, Yulia, Dani, Christian, Rudich, Assaf, Moussaieff, Arieh“…The differential abundance of phosphatidylcholines we found can be attributed at least partially to higher expression of phosphatidylethanolamine methyl transferase (PEMT). PEMT-deficient embryonic stem cells showed a dramatic decrease in adipogenesis, and the resulting adipocytes exhibited lower accumulation of lipid droplets, in line with the lower concentrations of glycerolipids in VAT. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto