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10521por Li, Ertao, Qin, Jianhui, Feng, Honglin, Li, Jinqiao, Li, Xiaofeng, Nyamwasa, Innocent, Cao, Yazhong, Ruan, Weibin, Li, Kebin, Yin, Jiao“…Notably, some immune-related genes, such as peptidoglycan recognition protein SC1 (PGRP-SC1), pro-phenoloxidase activating enzyme-I (PPAE-I) and glutathione s-transferase (GST), were induced at both treatment points. …”
Publicado 2021
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10522por Gong, Jin-Yu, Peng, Si-Yin, Xing, Kai, Fan, Li, Tan, Sheng-Lan, Luo, Zhi-Ying, Yuan, Hai-Yan, Xu, Ping, Luo, Jian-Quan“…The association between Glutathione S-transferase Pi 1(GSTP1) genetic polymorphism (rs1695, 313A>G) and cyclophosphamide-induced toxicities has been widely investigated in previous studies, however, the results were inconsistent. …”
Publicado 2021
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10523por Gan, Qinyi, Gong, Beilei, Sun, Manli, Cao, Zhujun, Zheng, Yuyan, Zhang, Yajie, Wen, Pengfei, Shen, Yuanbing, Hong, Lei, Hou, Tingting, Jia, Yuqin, Li, Wei, Li, Hecheng, Xie, Qing“…LFTs included alanine transaminase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, and total bilirubin. Patients were considered with abnormal LFTs when any value of these tests was higher than upper limit of normal. …”
Publicado 2021
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10524“…Cell apoptosis was assessed in vivo by caspase 3 detection in Western blots and measurement of apoptosis in neurons and glial cells by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. Apoptosis was analyzed by flow cytometry in HT22 cells. …”
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10525por Chen, Ke, Zeng, Jin, Sun, Yi, Ouyang, Wei, Yu, Gan, Zhou, Hui, Zhang, Yangjun, Yao, Weimin, Xiao, Wei, Hu, Junhui, Xing, Jinchun, Xiao, Kefeng, Wu, Lily, Chen, Zhiqiang, Ye, Zhangqun, Xu, Hua“…METHODS: Affinity purification and mass spectrometry (AP‐MS) screening, glutathione‐s‐transferase (GST) pull‐down and co‐immunoprecipitation (Co‐IP) assays were performed to detect the interacting proteins of HIF2α. …”
Publicado 2021
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10526“…METHODS: Lepeophtheirus salmonis microsomal glutathione S-transferase 1 like (LsMGST1L) and LsPGES3L were investigated by sequencing, phylogenetics, transcript localization and expression studies. …”
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10527por Jacobus, Ana Paula, Stephens, Timothy G., Youssef, Pierre, González-Pech, Raul, Ciccotosto-Camp, Michael M., Dougan, Katherine E., Chen, Yibi, Basso, Luiz Carlos, Frazzon, Jeverson, Chan, Cheong Xin, Gross, Jeferson“…All genomes of bioethanol yeasts have amplified SNO2(3)/SNZ2(3) gene clusters for vitamin B1/B6 biosynthesis, and display ubiquitous presence of a particular family of SAM-dependent methyl transferases, rare in S. cerevisiae. Widespread amplifications of quinone oxidoreductases YCR102C/YLR460C/YNL134C, and the structural or punctual variations among aquaporins and components of the iron homeostasis system, likely represent adaptations to industrial fermentation. …”
Publicado 2021
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10528por Shi, Qiong, Ni, Xiaomei, Lei, Ming, Xia, Quansong, Dong, Yan, Zhang, Qiao, Wang, Weiping“…METHODS: Co-immunoprecipitation (co-IP) and glutathione S-transferase (GST)-pulldown assays were employed to evaluate the interaction of ISL1 with CDK1. …”
Publicado 2021
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10529“…METHODS: Along with a brief review of the evidence available on HoFH we describe the treatment of two Saudi Arabian patients with HoFH diagnosed and treated in accordance with local clinical practices and with the microsomal triglyceride transferase protein inhibitor lomitapide. RESULTS: HoFH in Saudi Arabia is characterized by problems associated with consanguinity, a lack of access to lipoprotein apheresis, and pressures to proceed to liver transplant. …”
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10530por Peng, Hewei, Xie, Xiaoxu, Pan, Xinting, Zheng, Jing, Zeng, Yidan, Cai, Xiaoling, Hu, Zhijian, Peng, Xian-E“…Significant associations of red meat intakes with serum levels of γ-glutamyl transferase, alanine transaminase, aspartate aminotransferase, total triglyceride and high-density lipoprotein cholesterol were found (r(s) = 0.176; P < 0.001; r(s) = 0.128; P < 0.001; r(s) = 0.060; P = 0.016; r(s) = 0.085; P = 0.001; r(s) = − 0.074; P = 0.003). …”
Publicado 2021
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10531por Yu, Guo, Ali, Zakir, Sajjad Khan, Anam, Ullah, Kalim, Jamshaid, Humzah, Zeb, Alam, Imran, Muhammad, Sarwar, Sadia, Choi, Han-Gon, ud Din, Fakhar“…Advanced analyses including survival rate, immunohistopathology, and terminal deoxynucleotidyl transferase dUTP nick end labelling (TUNEL) assays were performed to evaluate apoptosis in vivo. …”
Publicado 2021
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10532“…We planned a subgroup analysis based on O(6)-methylguanine-DNA methyl-transferase (MGMT) status. We followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses. …”
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10533por Damerum, Annabelle, Smith, Hazel K., Clarkson, GJJ, Truco, Maria José, Michelmore, Richard W., Taylor, Gail“…Several promising candidate genes in this region were associated with WUE, including aquaporins, late embryogenesis abundant proteins, an abscisic acid-responsive element binding protein and glutathione S-transferases involved in redox homeostasis following drought stress were also identified. …”
Publicado 2021
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10534por He, Lin, Ip, Dennis Kai Ming, Tam, Greta, Lui, Vincent Chi Hang, Tam, Paul Kwong Hang, Chung, Patrick Ho Yu“…A total of 51 eligible studies were included in the systematic review, and data from 12 (4182 subjects) were extracted for meta-analysis regarding the following 2 domains: (1) serum matrix metallopeptidase-7 (MMP-7), interleukin33 (IL-33) and γ-glutamyl transferase (GGT) to differentiate BA from non-BA; (2) the aspartate aminotransferase to platelet ratio index (APRi) to predict post-KPE liver fibrosis/cirrhosis. …”
Publicado 2021
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10535por Yadav, Chandra Bhan, Tokas, Jayanti, Yadav, Devvart, Winters, Ana, Singh, Ram B., Yadav, Rama, Gangashetty, Prakash I., Srivastava, Rakesh K., Yadav, Rattan S.“…This identified 18 candidate genes related to antioxidant pathway genes (flavanone 7-O-beta-glycosyltransferase, GDSL esterase/lipase, glutathione S-transferase) residing within or near the association signal that can be selected for further functional characterization. …”
Publicado 2021
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10536por Garcia, Erika, Stratakis, Nikos, Valvi, Damaskini, Maitre, Léa, Varo, Nerea, Aasvang, Gunn Marit, Andrusaityte, Sandra, Basagana, Xavier, Casas, Maribel, de Castro, Montserrat, Fossati, Serena, Grazuleviciene, Regina, Heude, Barbara, Hoek, Gerard, Krog, Norun Hjertager, McEachan, Rosemary, Nieuwenhuijsen, Mark, Roumeliotaki, Theano, Slama, Rémy, Urquiza, Jose, Vafeiadi, Marina, Vos, Miriam B., Wright, John, Conti, David V., Berhane, Kiros, Vrijheid, Martine, McConnell, Rob, Chatzi, Lida“…Established liver injury biomarkers, including alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase, and cytokeratin-18, were measured in serum between ages 6–10 years. …”
Publicado 2021
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10537“…RESULTS: Aided by in silico retrobiosynthesis analysis, we designed a novel 3-phenylpropanol biosynthetic pathway extending from l-phenylalanine and comprising the phenylalanine ammonia lyase (PAL), enoate reductase (ER), aryl carboxylic acid reductase (CAR) and phosphopantetheinyl transferase (PPTase). We screened the enzymes from plants and microorganisms and reconstructed the artificial pathway for conversion of 3-phenylpropanol from l-phenylalanine. …”
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10538por Niazi, Yasmeen, Thomsen, Hauke, Smolkova, Bozena, Vodickova, Ludmila, Vodenkova, Sona, Kroupa, Michal, Vymetalkova, Veronika, Kazimirova, Alena, Barancokova, Magdalena, Volkovova, Katarina, Staruchova, Marta, Hoffmann, Per, Nöthen, Markus M., Dusinska, Maria, Musak, Ludovit, Vodicka, Pavel, Hemminki, Kari, Försti, Asta“…For the base excision repair pathway, the implicated genes PARP1 and PARP2 encode poly(ADP-ribosyl) transferases with multiple regulatory functions. PARP1 and PARP2 have an important role in maintaining genome stability through diverse mechanisms. …”
Publicado 2021
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10539por Martin, Brian, Vanderpool, Rebecca R., Henry, Brian L., Palma, Joshua B., Gabris, Beth, Lai, Yen-Chun, Hu, Jian, Tofovic, Stevan P., Reddy, Rajiv P., Mora, Ana L., Gladwin, Mark T., Romero, Guillermo, Salama, Guy“…Relaxin decreased Nrf2 and glutathione transferases but not glutathione-reductase. High-dose RLX improved pulmonary arterial compliance (measured by Doppler flow), suppressed VF even after burst-pacing, n = 2/6). …”
Publicado 2021
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10540por Borković-Mitić, Slavica, Stojsavljević, Aleksandar, Vujotić, Ljiljana, Matić, Siniša, Mitić, Bojan, Manojlović, Dragan, Pavlović, Slađan“…The following antioxidant parameters were determined: activities of total, manganese-containing, and copper/zinc-containing superoxide dismutase (TotSOD, MnSOD and CuZnSOD), activities of catalase, glutathione peroxidase, glutathione S-transferase, glutathione reductase and acetylcholine esterase (AChE), the concentrations of glutathione and sulfhydryl groups and of manganese (Mn), copper (Cu), zinc (Zn), and selenium (Se). …”
Publicado 2021
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