-
10921por Duggirala, Aparna, Kimura, Tomomi E., Sala-Newby, Graciela B., Johnson, Jason L., Wu, Yih-Jer, Newby, Andrew C., Bond, Mark“…Inhibiting RhoA activity, which regulates actin-polymerisation, by cAMP-elevation or pharmacologically with C3-transferase, or inhibiting its downstream kinase, ROCK, with Y27632, significantly inhibited CCN1 expression. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10922por Schlosser, Paul M., Bale, Ambuja S., Gibbons, Catherine F., Wilkins, Amina, Cooper, Glinda S.“…Although there are gaps in the database for dichloromethane genotoxicity (i.e., DNA adduct formation and gene mutations in target tissues in vivo), the positive DNA damage assays correlated with tissue and/or species availability of functional glutathione S-transferase (GST) metabolic activity, the key activation pathway for dichloromethane-induced cancer. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10923“…Galectin-8 pre-treatment dramatically enhanced cell adhesion to laminin and neuraminidase treatment also enhanced cell adhesion to laminin in combination with galectin-8. Rho inhibitor, C3-transferase pre-treatment resulted in inhibition of cell invasion to galectin-8. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10924por MacLeod, A. Kenneth, Fallon, Padraic G., Sharp, Sheila, Henderson, Colin J., Wolf, C. Roland, Huang, Jeffrey T.-J.“…We observed compensatory induction of several enzymes, including Cyps 2b10, 2c29, 2c37, 2c54, 2c55, 2e1, 3a11, and 3a13, carboxylesterase (Ces) 2a, and glutathione S-transferases (Gst) m2 and m3, along with down-regulation of hydroxysteroid dehydrogenases (Hsd) 11b1 and 17b6. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10925“…Oxidative stress markers such as total antioxidant status (TAS), serum levels of reduced (GSH) and oxidized (GSSG) glutathione, Gamma-glutamyl transferase (GGT) and malondialdehyde (MDA) were evaluated in patients infected with diverse HCV genotypes and those in the control group. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10926“…The effects of TW-37 alone or combined with cisplain on growth and apoptosis in bcl-2 overexpressed OVCAR3, OV-90 and SKOV3(DDP) cells was detected by MTT,clonogenic assay, ELISA and terminal deoxynucleotidyl transferase-mediated nick end labeling (TUNEL) assay. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10927“…The structure of PseH, together with the conservation of the active-site general acid among GNAT superfamily transferases, are consistent with a common catalytic mechanism for this enzyme that involves direct acetyl transfer from AcCoA without an acetylated enzyme intermediate. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10928por Harris, Donald G., Benipal, Prabhjot K., Cheng, Xiangfei, Burdorf, Lars, Azimzadeh, Agnes M., Pierson, Richard N.“…METHODOLOGY/PRINCIPAL FINDINGS: Confluent wild-type (WT, n = 48) and Gal transferase knock-out (GalTKO, which resist hyperacute rejection; n = 11) porcine endothelia were cultured in microfluidic channels. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10929por Zhang, Chuanzhen, Yan, Daojie, Wang, Shanshan, Xu, Changqing, Du, Wenjun, Ning, Tao, Liu, Changhong, Zhang, Meijuan, Hou, Ruiping, Chen, Ziping“…BACKGROUND: Nicotinamide phosphoribosyl transferase (Nampt) plays a crucial role in tumorigenesis. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10930“…Among all the suggested factors, it is more important that the level of endogenous jasmonates, carbohydrate metabolism, hydroxymethylglutaryl-CoA reductase (HMGR) and Hevea rubber transferase (HRT) in mevalonate (MVA) parthway for latex regeneration while the level of endogenous ethylene (ETH), lignin content of laticifer cell wall, antioxidants and glucanases for the duration of latex flow. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10931por Chen, Liao Y.“…We implement this hSMD approach for two ligand–protein complexes whose structures were determined and whose binding affinities were measured experimentally: caprylic acid binding to bovine β-lactoglobulin and glutathione binding to Schistosoma japonicum glutathione S-transferase tyrosine 7 to phenylalanine mutant. Our computed binding affinities agree with the experimental data within a factor of 1.5. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10932por Omondi, Bonaventure Aman, Latorre-Estivalis, Jose Manuel, Rocha Oliveira, Ivana Helena, Ignell, Rickard, Lorenzo, Marcelo Gustavo“…The set of genes included were: α-tubulin; β-actin; Glyceraldehyde-3-phosphate dehydrogenase; Eukaryotic initiation factor 1A; Glutathione-S-transferase; Serine protease; Succinate dehydrogenase; and Glucose-6-phosphate dehydrogenase. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10933por Zhang, Wei, Qiao, Lixing, Wang, Xinchao, Senthilkumar, Ravichandran, Wang, Fei, Chen, Baoan“…Cell cycle and apoptosis were detected using the terminal deoxyribonucleotidyl transferase (TdT)-mediated biotin-16-dUTP nick-end labeling (TUNEL) assay and flow cytometry (FCM). …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10934por ZHANG, WEIJIE, JIAO, HONGLIANG, ZHANG, XUDONG, ZHAO, RUIHUA, WANG, FENG, HE, WEI, ZONG, HONG, FAN, QINGXIA, WANG, LIUXING“…The aim of the present study was to investigate the correlation between the expression of DNA (cytosine-5)-methyltransferase 1 (DNMT1), glutathione S-transferase-P1 (GSTP1) and adenomatous polyposis coli (APC), and the methylation status of GSTP1 and APC in prostate cancer (PCa) and benign prostatic hyperplasia (BPH), and to examine its clinical significance. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10935por Wen, Yumin, Zhan, Yongli, Liu, Huijie, Zhao, Tingting, Yang, Liping, Zhang, Haojun, Dong, Xi, Li, Ping“…In situ cell apoptosis was detected by a terminal deoxynucleotidyl transferase-mediated uridine 5′-triphosphate-biotin nick end-labeling (TUNEL) assay. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10936por Zhang, Yan, Li, Sainan, He, Lei, Wang, Fan, Chen, Kan, Li, Jingjing, Liu, Tong, Zheng, Yuanyuan, Wang, Jianrong, Lu, Wenxia, Zhou, Yuqing, Yin, Qin, Xia, Yujing, Zhou, Yingqun, Lu, Jie, Guo, Chuanyong“…Combination therapy with UDCA and fenofibrate was more effective than UDCA monotherapy in improving alkaline phosphatase (mean difference [MD]: −90.44 IU/L; 95% confidence interval [CI]: −119.95 to −60.92; P<0.00001), gamma-glutamyl transferase (MD: −61.58 IU/L; 95% CI: −122.80 to −0.35; P=0.05), immunoglobulin M (MD: −38.45 mg/dL; 95% CI: −64.38 to −12.51; P=0.004), and triglycerides (MD: −0.41 mg/dL; 95% CI: −0.82 to −0.01; P=0.05). …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10937por Ariza, Xavier, Solà, Elsa, Elia, Chiara, Barreto, Rogelio, Moreira, Rebeca, Morales-Ruiz, Manuel, Graupera, Isabel, Rodríguez, Ezequiel, Huelin, Patricia, Solé, Cristina, Fernández, Javier, Jiménez, Wladimiro, Arroyo, Vicente, Ginès, Pere“…Other attractive biomarkers for ATN diagnosis were IL-18, albumin, trefoil-factor-3 (TFF-3) and glutathione-S-transferase-π (GST-π) Biomarkers with less accuracy for ATN AUCROC<0.8 were β2-microglobulin, calbindin, cystatin-C, clusterin and KIM-1 (kidney injury molecule-1). …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10938por Zhong, Yun, Cheng, Chun-zhen, Jiang, Nong-hui, Jiang, Bo, Zhang, Yong-yan, Wu, Bo, Hu, Min-lun, Zeng, Ji-wu, Yan, Hua-xue, Yi, Gan-jun, Zhong, Guang-yan“…The root unique changes included the down-regulation in genes of ubiquitin-dependent protein degradation pathway, secondary metabolism, cytochrome P450s, UDP-glucosyl transferases and pentatricopeptide repeat containing proteins. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10939“…FAS and sterol regulatory element-binding proteins 1 (SREBP1) mRNA gene expressions were increased (P<0.05) while the muscle-carnitine palmityl transferase (M-CPT) and peroxisome proliferators-activated receptorγ (PPARγ) mRNA (P<0.05) gene expressions were decreased in the muscles of the IUGR pigs by choline supplementation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
10940“…Proline dehydrogenase and delta-ornithine amino transferase-encoding genes, both involved in P5C synthesis in mitochondria are implicated in defense response of Nicotiana benthamiana and Arabidopsis thaliana against bacterial pathogens. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto