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11041por Tao, W., Yurkovich, M. E., Wen, S., Lebe, K. E., Samborskyy, M., Liu, Y., Yang, A., Liu, Y., Ju, Y., Deng, Z., Tosin, M., Sun, Y., Leadlay, P. F.“…A separate genetic locus encodes a cysteine desulfurase and a (thiouridylase-like) sulfur transferase to supply the sulfur atom for thiotetronate ring formation. …”
Publicado 2016
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11042“…TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) assay coupled to flow cytometry is one of the most promising methods for SDF quantification. …”
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11043“…This systematic review and meta-analysis aims to evaluate the diagnostic accuracy of the novel serological biomarkers intestinal fatty acid-binding protein (I-FABP), α-glutathione S-transferase (α-GST), d-lactate, ischemia modified albumin (IMA), and citrulline to detect AMI. …”
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11044por Tsuji, Daiki, Ikeda, Midori, Yamamoto, Keisuke, Nakamori, Harumi, Kim, Yong-Il, Kawasaki, Yohei, Otake, Aki, Yokoi, Mari, Inoue, Kazuyuki, Hirai, Keita, Nakamichi, Hidenori, Tokou, Umi, Shiokawa, Mitsuru, Itoh, Kunihiko“…In this genetic polymorphism association study, peripheral blood samples from 100 consecutive breast cancer outpatients, between August 2012 and September 2014, treated with doxorubicin and cyclophosphamide (AC) combination chemotherapy were genotyped for polymorphisms in adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1), cytochrome P450 (CYP) enzyme-coding genes (CYP2B6 and CYP3A5), glutathione S-transferase (GST), and excision repair cross-complementing 1 (ERCC1). …”
Publicado 2016
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11045por Kandhare, Amit D., Bodhankar, Subhash Laxmanrao, Mohan, Vishwaraman, Thakurdesai, Prasad A.“…RESULTS: Intratracheal BLM administration caused significant induction (P < 0.001) of hepatotoxicity and liver fibrosis reflected by elevated levels of serum aspartate transaminase (AST), alanine transaminase (ALT), total as well as direct bilirubin, and gamma-glutamyl transferase (GGT). Administration of SFSE-G (20 and 40 mg/kg, p.o.) significantly reduced (P < 0.001) levels of AST, ALT, and GGT and significantly increased (P < 0.001) the level of serum albumin. …”
Publicado 2017
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11046“…Myocardial apoptosis and fibrosis were examined by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling and Masson Trichrome staining, respectively. …”
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11047“…Apoptosis in lung tissues was detected by the terminal-deoxynucleoitidyl transferase mediated nick end-labeling (TUNEL) method. …”
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11048“…Terminal deoxynucleotidyl transferase nick end labelling (TUNEL) and sperm chromatin structure assay (SCSA) were most commonly utilized (30.6% for both), followed by sperm chromatin dispersion (SCD) (20.4%), single cell gel electrophoresis (Comet) (6.1%) and other methods (12.2%). …”
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11049“…Following 3 h reperfusion, flow cytometry and terminal deoxynucleotidyl transferase dUTP nick end labeling staining were performed to measure myocardial cell apoptosis. …”
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11050por Liu, Yu-Chi, Williams, Geraint P., George, Ben L., Soh, Yu Qiang, Seah, Xin Yi, Peh, Gary Swee Lim, Yam, Gary Hin Fai, Mehta, Jodhbir S.“…Clarity evaluation with transmittance measurements, cell-death assays with terminal deoxynucleotidyl transferase-mediated nick end labeling assay (TUNEL), collagen fibril spacing and necrotic response assessed with transmission electron microscopy (TEM), and immunohistochemistry analysis for human leukocyte antigens (HLAs) and CD45 for immunogenicity, and matrix metalloproteinase (MMP)-2 for keratocyte response, were undertaken at baseline, 48 h (short term), and 4 weeks (long term). …”
Publicado 2017
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11051por Sun, Fei, Li, Xin, Duan, Wen‐Qi, Tian, Wei, Gao, Ming, Yang, Jia, Wu, Xia‐Yang, Huang, Di, Xia, Wei, Han, Yan‐Na, Wang, Jia‐Xin, Liu, Yan‐Xin, Dong, Chang‐Jiang, Zhao, Dan, Ban, Tao, Chu, Wen‐Feng“…Cell viability, apoptosis, TGFβR3, and mitogen‐activated protein kinase signaling were assessed by methylthiazolyldiphenyl‐tetrazolium bromide assay, terminal deoxynucleotidyl transferase‐mediated dUTP nick end labeling assay, immunofluorescence, electron microscopy, and Western blotting. …”
Publicado 2017
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11052por Tang, Yao, Cai, Qi-Hang, Wang, Yong-Jian, Fan, Shao-Hua, Zhang, Zi-Feng, Xiao, Meng-Qi, Zhu, Jin-Yu, Wu, Dong-Mei, Lu, Jun, Zheng, Yuan-Lin“…The cell apoptotic rates of AECs were analyzed by terminal deoxynucleotidyl transferase (TdT) mediated dUTP-biotin nick end-labeling (TUNEL) staining. …”
Publicado 2017
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11053“…Glucose, total proteins (TP), urea, creatinine, cystatin C, total bilirubin (BT), total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides (Tg), uric acid (UA), high-sensitivity C-reactive protein, gamma-glutamyl transferase (GGT), aspartate-aminotransferase (AST), alanine-aminotransferase and lactate-dehydrogenase (LD) were studied. …”
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11054por Zhang, Fan, Ru, Neng, Shang, Zheng-Hui, Chen, Jian-Feng, Yan, Chao, Li, Yun, Liang, Jie“…A concomitant decline in edema, inflammatory markers (myeloperoxidase, tumor necrosis factor-α and nuclear factor κB p65), the apoptotic marker caspase-3 and the number of cells with terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling was also observed in the DZ and MP groups. …”
Publicado 2017
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11055“…Reactive oxygen species (ROS) in H9c2 cells was measured by flow cytometry, and the activities of the antioxidant enzymes CAT, SOD, GSH‐px, glutathione‐S‐transferase, TNF‐α, IL‐6 and IL‐1β in cellular supernatant were measured. …”
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11056por Rydman, Eric, Comasco, Erika, Pettersson, H., Oreland, L., Ponzer, S., Ottosson, C.“…BACKGROUND: The COMT (Catechol-O-Methyl Transferase) gene may influence a person’s vulnerability to develop long-term pain and some COMT single nucleotide polymorphisms (SNPs) may associate with patterns of acute or chronic pain. …”
Publicado 2017
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11057por Peng, Wenhui, Li, Miaoxin, Li, Hailing, Tang, Kai, Zhuang, Jianhui, Zhang, Jianguo, Xiao, Jingjing, Jiang, Hui, Li, Dali, Yu, Yongchun, Sham, Pak C., Nattel, Stanley, Xu, Yawei“…Biochemical analyses of MYL4 p.E11K mutation rats showed activation of proapoptotic and profibrotic signaling, along with increased atrial‐cardiomyocyte terminal deoxynucleotidyl transferase dUTP nick end labeling staining, suggesting enhanced apoptotic cell death, findings that were mimicked by in vitro adenoviral transfer of the mutant gene to neonatal‐rat cardiomyocytes. …”
Publicado 2017
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11058“…RESULTS: Using a combination of bacterial two-hybrid (B2H), glutathione S-transferase (GST) pull-down assays, and surface plasmon resonance (SPR), nine interactions were observed among the eight gonococcal cell division proteins tested. …”
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11059por El-Ashker, Maged R., Salama, Mohamed F., El-Boshy, Mohamed E., Abo El-Fadle, Eman A.“…Serum total protein, albumin, creatinine, urea, aspartate aminotransferase, gamma-glutamyl transferase, and total bilirubin levels were also higher in non-survivors than those of survivors (P < 0.05). …”
Publicado 2018
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11060por Anandanarayanan, Arun, Raina, Opinder Krishen, Lalrinkima, Hniang, Rialch, Ajayta, Sankar, Muthu, Varghese, Anju“…Here we optimized conditions for RNAi in the liver fluke F.gigantica targeting six genes including superoxide dismutase (SOD), σ class of glutathione-s-transferase (GST), cathepsin (Cat) L1-D, Cat B1, Cat B2 and Cat B3 that showed robust transcriptional silencing of the targets following exposure of the newly excysted juveniles (NEJs) to long (170–223 nt) dsRNA. …”
Publicado 2017
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