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11281“…Liver and kidney function tests such as alanine amino transferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), bilirubin, urea and uric acid were determined in the serum and organs homogenates. …”
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11282por Awed, Eman M., Sadek, Kadry M., Soliman, Magdy K., Khalil, Riad H., Younis, Elsayed M., Abdel-Warith, Abdel-Wahab A., Van Doan, Hien, Dawood, Mahmoud A.O., Abdel-Latif, Hany M.R.“…Moreover, the expression of hepatic SOD, GSH-Px, and glutathione-S-transferase (GST) genes was also determined. It was found that tissue CAT, SOD, and GSH-Px activities as well as the T-AOC levels were significantly decreased in the SS group (p < 0.05). …”
Publicado 2020
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11283por Ekine-Afolabi, Bene A., Njan, Anoka A., Rotimi, Solomon O., R. I., Anu, Elbehi, Attia M., Cash, Elizabeth, Adeyeye, Ademola“…This review discusses important dietary factors in relation to the expression of EV-associated ncRNAs in CRC, the impact of diet on the colon ecosystem with particular emphasis on molecular mechanisms of interactions in the ecosystem, the influence of homeostasis regulators such as glutathione, and its conjugating enzyme-glutathione S-transferase (GST) polymorphism on intestinal ecosystem, oxidative stress response, and its relationship to DNA adduct fighting enzyme-0-6-methylguanine-DNA methyltransferase. …”
Publicado 2020
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11284“…It has been reported that molybdate is involved in a futile energy cycle with the sulfate-activating enzyme, sulfate adenylyl transferase (Sat), which results in loss of cellular ATP. …”
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11285por Choi, Soo In, Son, Joo Hee, Kim, Nayoung, Kim, Yong Sung, Nam, Ryoung Hee, Park, Ji Hyun, Song, Chin-Hee, Yu, Jeong Eun, Lee, Dong Ho, Yoon, Kichul, Min, Huitae, Kim, Yeon-Ran, Seok, Yeong-Jae“…Enzymes required for producing butyrate—acetyl-CoA transferase, butyryl-CoA dehydrogenase, and butyrate kinase—were not predicted by PICRUSt. …”
Publicado 2021
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11286por Alanazi, Ahmed Z., Alqahtani, Faleh, Mothana, Ramzi A. A., Mohany, Mohamed, Abuohashish, Hatem M., Ahmed, Mohammed M., Al-Rejaie, Salim S.“…In liver, thiobarbituric acid reactive substances (TBARSs) and reduced glutathione (GSH) as well as the proinflammatory cytokines and enzymatic activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reeducates (GR), and glutathione-S-transferase (GST) were assayed. Finally, the degree of hepatic tissue damage was evaluated histologically. …”
Publicado 2020
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11287por Brahma, Manoja K., Ha, Chae‐Myeong, Pepin, Mark E., Mia, Sobuj, Sun, Zhihuan, Chatham, John C., Habegger, Kirk M., Abel, Evan Dale, Paterson, Andrew J., Young, Martin E., Wende, Adam R.“…Elevated blood glucose (type 1 diabetes mellitus and high‐fat diet mice) was associated with reduced cardiac expression of β‐hydroxybutyrate‐dehydrogenase and succinyl‐CoA:3‐oxoacid CoA transferase. Increased myocardial β‐hydroxybutyrate levels were also observed in type 1 diabetes mellitus mice, suggesting a mismatch between ketone body availability and utilization. …”
Publicado 2020
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11288por Wang, Jessie, Dey, Abhinav, Kramer, Adam H., Miao, Yuan, Liu, Juan, Baker, Lisa, Friedman, Joel M., Nacharaju, Parimala, Chuck, Roy S., Zhang, Cheng, Sharp, David J.“…Toxicity assays were performed to assess for apoptosis (terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling [TUNEL] assay) and nerve damage (whole mount immunochemical staining). …”
Publicado 2021
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11289por Zhang, Xiaofang, Mens, Michelle M. J., Abozaid, Yasir J., Bos, Daniel, Darwish Murad, Sarwa, de Knegt, Robert J., Ikram, M. Arfan, Pan, Qiuwei, Ghanbari, Mohsen“…RESULTS: Cross‐sectional analysis showed 61 miRNAs significantly associated with serum gamma‐glutamyl transferase and/or alkaline phosphatase levels (Bonferroni‐corrected P < 8.46 × 10(−5)). …”
Publicado 2020
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11290por Malekinezhad, Pouyan, Ellestad, Laura E., Afzali, Nazar, Farhangfar, Seyed Homayoun, Omidi, Arash, Mohammadi, Abbas“…Feeding PCAFB and PCOTA diets increased feed conversion ratio (FCR), serum aspartate aminotransferase (AST), lactate dehydrogenase (LDH), alanine aminotransferase (ALT), and gamma-glutamyl transferase (GGT) activities, serum urea, and liver lesions compared with NC. …”
Publicado 2020
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11291por Jerotic, Djurdja, Suvakov, Sonja, Matic, Marija, Alqudah, Abdelrahim, Grieve, David J., Pljesa-Ercegovac, Marija, Savic-Radojevic, Ana, Damjanovic, Tatjana, Dimkovic, Nada, McClements, Lana, Simic, Tatjana“…Deletion polymorphism of glutathione S-transferase M1 (GSTM1), a phase II detoxification and antioxidant enzyme, increases susceptibility to end-stage renal disease (ESRD) as well as the development of cardiovascular diseases (CVD) among ESRD patients and leads to their shorter cardiovascular survival. …”
Publicado 2021
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11292por Lee, Syng-ook, Chun, So Young, Lee, EunHye, Kim, Bomi, Yoon, BoHyun, Gil, Haejung, Kim, Dae Hwan, Jang, Byung Ik, Lee, Dong Woo, Yoo, Eun Sang, Park, Dong Jin, Lee, Jun Nyung, Han, Man-Hoon, Kim, Bum Soo, Song, Phil Hyun, Kwon, Tae Gyun, Ha, Yun-Sok“…Terminal deoxynucleotidyl transferase dUTP nick-end labeling- (TUNEL-) positive cells and the secretion of apoptosis-related molecules (Fas and caspase 3) were significantly reduced in the pretreated groups compared with the other groups. …”
Publicado 2021
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11293por Čítek, Jindřich, Brzáková, Michaela, Hanusová, Lenka, Hanuš, Oto, Večerek, Libor, Samková, Eva, Křížová, Zuzana, Hoštičková, Irena, Kávová, Tereza, Straková, Karolina, Hasoňová, Lucie“…Polymorphisms in the acyl-CoA diacylgycerol transferase 1 (DGAT1), leptin (LEP), fatty acid synthase (FASN), stearoyl CoA desaturase 1 (SCD1), casein beta (CSN2), casein kappa (CSN3), and lactoglobulin beta genes were genotyped, and association analysis was performed. …”
Publicado 2021
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11294por Torra, Joel, Montull, José María, Taberner, Andreu, Onkokesung, Nawaporn, Boonham, Neil, Edwards, Robert“…Additionally, HR populations contained enhanced amounts of an ortholog of the glutathione transferase phi (F) class 1 (GSTF1) protein, a functional biomarker of non-target-site resistance (NTSR), as confirmed by enzyme-linked immunosorbent assays. …”
Publicado 2021
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11295por Mascarenhas, Leo, Ogawa, Chitose, Laetsch, Theodore W., Weigel, Brenda J., Bishop, Michael W., Krystal, Julie, Borinstein, Scott C., Slotkin, Emily K., Muscal, Jodi A., Hingorani, Pooja, Levy, Donna E., Mo, Gary, Shahir, Ashwin, Wright, Jennifer, DuBois, Steven G.“…Three dose‐limiting toxicities (DLTs) occurred during olaratumab monotherapy (at 15 mg/kg, grade [G] 4 alanine aminotransferase [ALT]; at 20 mg/kg, G3 lung infection and G3 gamma‐glutamyl transferase). One DLT occurred during vincristine/irinotecan with olaratumab 20 mg/kg therapy (G3 ALT). …”
Publicado 2021
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11296“…Next, hippocampal tissue injury and cell apoptosis were examined by hematoxylin-eosin (HE) and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling (TUNEL) staining. …”
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11297“…Univariate logistic regression analysis showed that gender, history of hepatitis/cirrhosis, and preoperative bilirubin, albumin, coagulation function, albumin-bilirubin ratio, aspartate amino-transferase-to-platelet ratio index (APRI), Model for End-Stage Liver Disease score, spleen volume (SV), spleen volume/liver volume ratio (SV/LV), and relative remnant liver volume were statistically associated with the occurrence of PHLF (all P < 0.05). …”
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11298“…Aim of this study is to evaluate serum gamma-glutamyl transferase (GGT) activity (marker of oxidative stress) and high sensitivity C reactive protein (hsCRP) level (an inflammatory marker) in type 2 DM subjects with good and poor glycemic control. …”
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11299por Torrini, Consuelo, Nguyen, Trang, Shu, Chang, Mela, Angeliki, Humala, Nelson, Mahajan, Aayushi, Karpel-Massler, Georg, Bruce, Jeffrey, Canoll, Peter, Siegelin, Markus“…H3K27ac), which was rescued by genetic and pharmacological inhibition of lactic acid-uptake, ATP-citrate lyase, p300 histone-acetyl-transferase and OXPHOS, resulting in reversal of lactate mediated protection from cell death. …”
Publicado 2021
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11300por Silva, Carla O., Simões, Tiago, Félix, Rafael, Soares, Amadeu M.V.M., Barata, Carlos, Novais, Sara C., Lemos, Marco F.L.“…Antioxidant defenses superoxide dismutase (SOD) and glutathione-S-transferase (GST), oxidative damage endpoints lipid peroxidation (LPO) and DNA damage, the neuronal parameter acetylcholinesterase (AChE), and the fatty acid profile were evaluated. …”
Publicado 2021
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