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11361“…Urinary cadmium levels and the following liver function parameters were measured: alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyl transferase (GGT), total bilirubin (TB), and alkaline phosphatase (ALP). …”
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11362“…After behavioral tests, neuronal apoptosis was detected by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay, and potential mechanisms were determined using western blotting and quantitative real-time PCR. …”
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11363“…At 1 week postoperatively, the four groups of rats were euthanized, and the Achilles tendon tissues were isolated for histological staining, immunohistochemistry (IHC), immunofluorescence, Sirius Red (SR) staining, and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling assay. …”
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11364“…The levels of some Nrf2-dependent cytoprotective and detoxifying proteins, i.e., glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), glutamate cysteine ligase catalytic subunit (GCLC), glutathione synthetase (GSS), NAD(P) H dehydrogenase quinone 1 (NQO1), UDP-glucumno-syltransferase 1 (UGT1), and heme oxygenase 1 (HO-1); glutathione (GSH); metallothionein (MT1); and glutamate-cysteine ligase (GCL) mRNA were measured. …”
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11365por Bai, Wen-wu, Wang, Hao, Gao, Chun-hua, Liu, Ke-yin, Guo, Bing-xiu, Jiang, Fan, Zhang, Ming-xiang, Li, Chen, Qin, Wei-dong“…Moreover, terminal deoxyribonucleotidyl transferase- (TDT-) mediated dUTP nick-end labeling (TUNEL) assay showed that Ang IV infusion reduced AMI-induced cardiomyocyte apoptosis. …”
Publicado 2021
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11366por Iheagwam, Franklyn Nonso, Batiha, Gaber El-Saber, Ogunlana, Olubanke Olujoke, Chinedu, Shalom Nwodo“…Induction of diabetes significantly (p < 0.05) reduced superoxide dismutase, glutathione-S-transferase, and peroxidase activities. Glutathione and protein stores were significantly (p < 0.05) depleted, while glucose, MDA, interleukin-six (IL-6), and tumour necrosis factor-α (TNF-α) concentrations were significantly (p < 0.05) increased. …”
Publicado 2021
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11367“…To further investigate the underlying mechanism of increased fecundity after exposure to the LC(10) dose of imidacloprid, we examined the expression levels of vitellogenin (Vg), Vg receptor (VgR) and caspases in the ovaries of SBPH, and observed the apoptosis by terminal deoxynucleotidyl transferase (TDT)-mediated dUTP-digoxigenin nick end labeling (TUNEL). qRT-PCR results indicated that the expression levels of Vg, VgR and four caspase genes were all significantly increased by the LC(10) dose of imidacloprid, and TUNEL assays suggested that the frequency of apoptosis was significantly higher in the SBPH treated by the LC(10) dose of imidacloprid, suggesting a potential correlation between the increased fecundity and the apoptosis of SBPH ovarioles. …”
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11368por Zhou, Ke, Tian, Ke-yong, Liu, Xin-qin, Liu, Wei, Zhang, Xin-yu, Liu, Jia-yun, Sun, Fei“…The potential otopathogenic effects of V. alginolyticus were determined through the performance of cell viability, cell apoptosis, and cell death assays in tympanic membrane (TM) keratinocytes and HEI-OC1 cells treated with V. alginolyticus-conditioned medium using cell-counting kit (CCK)-8 assay, a wound-healing migration assay, Annexin V/propidium iodide (PI) flow cytometric analysis, and terminal deoxynucleotidyl transferase deoxyuridine triphosphate (dUTP) nick-end labeling (TUNEL staining). …”
Publicado 2021
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11369por Das, Poulami, Xu, Wendy Kaichun, Gautam, Amit Kumar Singh, Lozano, Mary M., Dudley, Jaquelin P.“…Furthermore, purified glutathione S-transferase (GST)-tagged M57-58 and M59-61 demonstrated reduced ability to oligomerize compared to tagged wild-type SP. …”
Publicado 2022
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11370“…Both constructs are composed of sequences encoding a prenyl transferase and a respective S. habrochaites terpene synthase, as well as enhanced green fluorescent protein as a visible marker. …”
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11371por Čítek, Jindřich, Brzáková, Michaela, Hanusová, Lenka, Hanuš, Oto, Večerek, Libor, Samková, Eva, Jozová, Eva, Hoštičková, Irena, Trávníček, Jan, Klojda, Martin, Hasoňová, Lucie“…Polymorphisms in the casein alpha S1 (CSN1S1), beta-casein (CSN2), kappa-casein (CSN3), beta-lactoglobulin (LGB), acyl-CoA diacylglycerol transferase 1 (DGAT1), leptin (LEP), fatty acid synthase (FASN), stearoyl CoA desaturase 1 (SCD1), and 1-acylglycerol-3-phosphate O-acyltransferase 6 (AGPAT6) genes were genotyped, and association analysis to the SCS in the cow’s milk was performed. …”
Publicado 2022
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11372por He, Mingyan, Hu, Jing, Fang, Tingting, Tang, Wenqing, Lv, Bei, Yang, Biwei, Xia, Jinglin“…Additionally, the mechanism by which PCSK9 mediated dissociation of glutathione S-transferase Pi 1 (GSTP1) dimers and phosphorylation of the Jun N-terminal kinase (JNK) pathway components were investigated. …”
Publicado 2022
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11373“…The subcellular responses to food type and availability were assayed using a suite of biomarkers – antioxidant enzymes [superoxide dismutases (SOD), catalase (CAT), and glutathione S-transferases (GST)] and acetylcholinesterase (AChE). …”
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11374“…Multivariate analysis revealed that the significant independent risk factors for dMMR-related CRC were younger age (OR: 0.979, 95% CI: 0.960–0.998), larger tumour diameter (OR: 1.313, 95% CI: 1.162–1.484), poor differentiation, no peripheral nerve invasiveness (OR: 3.018, 95% CI: 1.258–7.239), right-side colon cancer (OR: 10.821, 95% CI: 4.895–23.922), Bcl-2 positivity (OR: 0.209, 95% CI: 0.095–0.458), topoisomerase II negativity (OR: 3.333, 95% CI: 1.563–7.103) and glutathione S-transferase (GST) negativity (OR: 1.748, 95% CI: 1.009–3.027). …”
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11375por Ding, Shengnan, Yang, Weimin, Sun, Xiaodong, Guo, Yan, Zhao, Guangjie, Yang, Jinzhu, Zhang, Lei, Lv, Guoyue“…Alanine transaminase and gamma-glutamyl transferase were used for building the clinical model, and the AUC was 0.784 in the total cohort. …”
Publicado 2022
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11376por Abdel-Latif, Raghda T., Wadie, Walaa, Abdel-mottaleb, Yousra, Abdallah, Dalaal M., El-Maraghy, Nabila N., El-Abhar, Hanan S.“…The apoptotic effect was confirmed by transferase dUTP nick-end labeling assay. Moreover, these drugs inhibited colon content of p-Akt, β-catenin, and cyclin D1 immunoreactivity. …”
Publicado 2022
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11377por Vyas, Ruchi, Kesari, Kavindra Kumar, Slama, Petr, Roychoudhury, Shubhadeep, Sisodia, Rashmi“…Reciprocal elevation was observed in related enzymes, that is, glutathione S-transferase activity (GST), glutathione reductase (GR), and glutathione peroxidase activity (GPx). …”
Publicado 2022
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11378por Kopalli, Spandana Rajendra, Cha, Kyu-Min, Cho, Jae Youl, Kim, Si-Kwan, Koppula, Sushruta“…Further, the decreased antioxidant enzymes (glutathione-S-transferase mu5, glutathione peroxidase 4 and peroxiredoxin 3), spermatogenesis-related factors (nectin-2 and inhibin-α) and testosterone levels in H(2)O(2)-exposed TM3 cells were significantly (p < 0.05 ∼ p < 0.001) ameliorated by COR. …”
Publicado 2022
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11379por Suleiman, Joseph Bagi, Mohamed, Mahaneem, Abu Bakar, Ainul Bahiyah, Zakaria, Zaida, Othman, Zaidatul Akmal, Nna, Victor Udo“…There were significant decreases in the activities of antioxidant enzymes [glutathione-S-transferase (GST), superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), glutathione reductase (GR)], glutathione (GSH)] and total antioxidant capacity (TAC) levels and mRNA expressions of nuclear factor erythroid 2–related factor 2 (Nrf2), superoxide dismutase (Sod), catalase (Cat) and glutathione peroxidase (Gpx) in the obese group relative to the control group. …”
Publicado 2022
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11380“…To control the heavy metal-induced oxidative damage, A. retroflexus invested in detoxification (metallothionein and phytochelatins, glutathione and glutathione-S-transferase (GST). At the organ level, oxidase damage (H(2)O(2), lipid and protein peroxidation) was observed, particularly in the roots. …”
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