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11541por Naegeli, Hanspeter, Birch, Andrew Nicholas, Casacuberta, Josep, De Schrijver, Adinda, Gralak, Mikołaj Antoni, Jones, Huw, Manachini, Barbara, Messéan, Antoine, Nielsen, Elsa Ebbesen, Nogué, Fabien, Robaglia, Christophe, Rostoks, Nils, Sweet, Jeremy, Tebbe, Christoph, Visioli, Francesco, Wal, Jean‐Michel, Álvarez, Fernando, Ardizzone, Michele, Liu, Yi, Neri, Franco Maria, Ramon, Matthew“…Soybean DAS‐44406‐6 expresses 5‐enolpyruvyl‐shikimate‐3‐phosphate synthase (2mEPSPS), conferring tolerance to glyphosate‐based herbicides, aryloxyalkanoate dioxygenase (AAD‐12), conferring tolerance to 2,4‐dichlorophenoxyacetic acid (2,4‐D) and other related phenoxy herbicides, and phosphinothricin acetyl transferase (PAT), conferring tolerance to glufosinate ammonium‐based herbicides. …”
Publicado 2017
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11542por Yan, Li-Ting, Wang, Li-Li, Yao, Jia, Yang, Ya-Ting, Mao, Xiao-Rong, Yue, Wei, Mao, Yong-Wu, Zhou, Wei, Chen, Qing-Feng, Chen, Yu, Duan, Zhong-Ping, Li, Jun-Feng“…The present study aimed to evaluate the value of TBA/TC in the diagnosis of cirrhosis and the relationship between TBA/TC and significant liver fibrosis in chronic hepatitis B virus (HBV) infected patients without cholestasis. 667 patients with alkaline phosphatase (ALP) ≤ 1.5 upper limit of normal (ULN) and gamma-glutamyl transferase (GGT) ≤ 3 ULN were rigorously included in this cross-sectional study. …”
Publicado 2020
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11543por Kang, Yewon, Kim, Sae-Hoon, Park, So-Young, Park, Bo Young, Lee, Ji-Hyang, An, Jin, Won, Ha-Kyeong, Song, Woo-Jung, Kwon, Hyouk-Soo, Cho, You Sook, Moon, Hee-Bom, Shim, Ju Hyun, Yang, Min-Suk, Kim, Tae-Bum“…Among patients with alanine transferase (ALT) ≤ 120 IU/L and total bilirubin (TB) ≤ 2.4 mg/dL in blood test results within 48 hours of admission, those who either had 1) ALT > 120 IU/L and TB > 2.4 mg/dL or 2) ALT > 200 IU/L at least once during hospitalization were identified. …”
Publicado 2020
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11544por Chang, Jia-Feng, Liu, Shih-Hao, Lu, Kuo-Cheng, Ka, Shuk-Man, Hsieh, Chih-Yu, Ho, Chun-Ta, Lin, Wei-Ning, Wen, Li-Li, Liou, Jian-Chiun, Chang, Shu-Wei, Wu, Chang-Chin, Wang, Ting-Ming, Li, Yen-Yao“…CKD arteries exhibited lower α-SMA, higher expressions of caspase-3 and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL), indicative of contractile VSMC loss, and apoptosis. …”
Publicado 2020
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11545“…METHODS: Taiwanese type 2 diabetes patients with inadequate control on insulin secretagogues and metformin, with no history of significant alcohol ingestion, with mildly elevated serum aspartate amino-transferase (AST) and/or alanine aminotransferase (ALT) and a diagnosis of fatty liver determined by ultrasonography were enrolled. …”
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11546por O'Hara, Geraldine, Mokaya, Jolynne, Hau, Jeffrey P, Downs, Louise O, McNaughton, Anna L, Karabarinde, Alex, Asiki, Gershim, Seeley, Janet, Matthews, Philippa C, Newton, Robert“…We derived fibrosis scores (aspartate aminotransferase (AST) to Platelet Ratio Index (APRI), fibrosis-4, gamma-glutamyl transferase (GGT) to platelet ratio (GPR), red cell distribution width to platelet ratio and S-index). …”
Publicado 2020
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11547por Kandel, Shyam L., Hulse-Kemp, Amanda M., Stoffel, Kevin, Koike, Steven T., Shi, Ainong, Mou, Beiquan, Van Deynze, Allen, Klosterman, Steven J.“…In Solomon, the hypersensitive inducible genes such as pathogenesis-related gene PR-1, glutathione-S-transferase, phospholipid hydroperoxide glutathione peroxidase and peroxidase were significantly up-regulated uniquely at 48 hpi and genes involved in zinc finger CCCH protein, glycosyltransferase, 1-aminocyclopropane-1-carboxylate oxidase homologs, receptor-like protein kinases were expressed at 48 hpi through 168 hpi. …”
Publicado 2020
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11548por Lasman, N., Shalom, M., Turpashvili, N., Goldhaber, G., Lifshitz, Y., Leibowitz, E., Berger, G., Saltzman-Shenhav, G., Brom, A., Cohen, D., Avaky, C., Segal, G.“…Low activity of the enzyme ALT (Alanine amino-transferase) in the blood is a known indicator for sarcopenia and frailty, however, no previous studies addressed the association of low ALT amongst patients hospitalized due to COPD exacerbation and long-term survival. …”
Publicado 2020
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11549por Pourkeramati, Alemeh, Zare Mehrjardi, Ehsan, Dehghan Tezerjani, Masoud, Seifati, Seyed Morteza“…BACKGROUND: Coronary artery disease (CAD) is a multifactorial disease that may be caused by the interaction between environmental and genetic risk factors. Glutathione S-transferases (GSTs) are known to participate in detoxification and metabolism of a wide range of xenobiotic compounds and oxidative stress products. …”
Publicado 2020
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11550por Wu, Qing-Juan, Lv, Wen-Liang, Li, Juan-Mei, Zhang, Ting-Ting, Zhou, Wen-hui, Zhang, Qiang, Wang, Jiu-Chong, Wang, Qing-Nan, Zhang, Ruo-Xuan, Zhao, Xin, Chen, Si-Tong, Liu, Shuang, Li, Gao-Hui, Cao, Zheng-Min, Xu, Lei, Chen, Jing“…The secondary outcome measures are hepatitis B virus DNA negative rate, hepatitis B surface antigen negative rate, hepatitis B e antigen seroconversion rate, liver function (alanine aminotransferase, aspartate aminotransferase , gamma-glutamyl transferase , alkaline phosphatase , serum albumin, and total bilirubin), spleen thickness, evaluation scores of patients’ clinical symptoms, and safety assessment. …”
Publicado 2020
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11551por Zou, Xiaojing, Fang, Minghao, Li, Shusheng, Wu, Liang, Gao, Bing, Gao, Hong, Ran, Xiao, Bian, Yi, Li, Renjie, ShanshanYu, Ling, Jianmin, Li, Donghui, Tian, Deying, Huang, Jiao“…RESULTS: Of the 105 patients with SARS-CoV-2 and chronic HBV coinfection, elevated levels of liver test were observed in several patients at admission, including elevated levels of alanine aminotransferase (22, 20.95%), aspartate aminotransferase (29, 27.62%), total bilirubin (7, 6.67%), gamma-glutamyl transferase (7, 6.67%), and alkaline phosphatase (1, 0.95%). …”
Publicado 2021
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11552“…In contrast, significant negative correlations of glutathione S-transferase (GST) and vacuolar invertase (vacInv) both within source and sink were found with NGS and HI. …”
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11553por Liu, Huanhuan, Zhang, Jing, Yuan, Jian, Jiang, Xiaolong, Jiang, Lingyan, Li, Zhenjing, Yin, Zhiqiu, Du, Yuhui, Zhao, Guang, Liu, Bin, Huang, Di“…Specifically, p-coumaric acid caused the most extensive transcriptomic disturbances, particularly affecting the gene expressions of ribosome proteins and the assembly of flagella, DNA replication, repair, and recombination; the addition of syringaldehyde caused significant metabolic disturbances on the gene expressions of ribosome proteins, starch and sucrose metabolism; vanillin mainly disturbed purine metabolism, sporulation and signal transduction; and ferulic acid caused a metabolic disturbance on glycosyl transferase-related gene expressions. CONCLUSION: This study uncovers novel insights into the inhibitory mechanisms of PCs for the first time and provides guidance for future metabolic engineering efforts, which establishes a powerful foundation for the development of phenol-tolerant strains of C. acetobutylicum for economically sustainable ABE production with high productivity from lignocellulosic biomass.…”
Publicado 2020
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11554“…Apoptotic cells were checked by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay and activities of caspase-3 and caspase-8 enzyme were tested. …”
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11555por Qi, Xiaoqiang, Yang, Ming, Ma, Lixin, Sauer, Madeline, Avella, Diego, Kaifi, Jussuf T, Bryan, Jeffrey, Cheng, Kun, Staveley-O’Carroll, Kevin F, Kimchi, Eric T, Li, Guangfu“…Tumor progression was monitored by MRI; tumor necrosis and apoptosis were detected by H&E and terminal deoxynucleotidyl transferase dUTP nick end labeling; immune reaction was defined by flow cytometry; and signaling molecules were examined with real-time PCR (qPCR), western blot, and immunohistochemical staining. …”
Publicado 2020
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11556por Ismy, Jufriady, Sugandi, Suwandi, Rachmadi, Dedi, Hardjowijoto, Sunaryo, Mustafa, Akhmad“…Apoptotic index is calculated based on the reaction introduction 3OH end of fragmentation of DNA by the enzyme terminal transferase in preparations with TUNEL staining reagents. …”
Publicado 2020
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11557“…The apoptosis of hippocampal neurons was detected by terminal deoxynucleotidyl transferase transfer‑mediated dUTP nick end‑labeling (TUNEL) assay and flow cytometry. …”
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11558por Naiki-Ito, Aya, Kato, Hiroyuki, Naiki, Taku, Yeewa, Ranchana, Aoyama, Yoshinaga, Nagayasu, Yuko, Suzuki, Shugo, Inaguma, Shingo, Takahashi, Satoru“…Regarding carcinogenesis, the number and area of glutathione S-transferase placental form (GST-P)-positive preneoplastic hepatic foci were significantly increased in Cx32ΔTg versus Wt rats. …”
Publicado 2020
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11559por Akbar, Sehrish, Wei, Yao, Yuan, Yuan, Khan, Muhammad Tahir, Qin, Lifang, Powell, Charles A., Chen, Baoshan, Zhang, Muqing“…To scavenge the ROS, the Badila genotype illustrated a substantial enhancement of antioxidants i.e. glutathione s-transferase (GST), as compared to its resistant counterpart. …”
Publicado 2020
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11560por Zhao, Haiyan, Wang, Jianshe, Qu, Yunfang, Peng, Renhai, Magwanga, Richard Odongo, Liu, Fang, Huang, Jinling“…Transcriptomic and proteomic results showed that UDP-glucuronosyl/UDP-glucosyltransferase, 60S ribosomal protein L13a-4-like, and glutathione S-transferase were upregulated; while heat shock protein Hsp20, ATPase, F0 complex, and subunit D were downregulated at the microspore abortion stage of Yamian A. …”
Publicado 2020
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