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11561“…Several studies have reported that mutations of dihydropyrimidine dehydrogenase (DPYD) and glutathione S-transferase pi-1 (GSTP1) polymorphisms are related to chemotherapy-related adverse events. …”
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11562por Gan, Weiqiang, Li, Jianguo, Zhang, Chunlan, Chen, Xuefu, Lin, Chaoshuang, Gao, Zhiliang“…HBV DNA, alanine amino transferase (ALT), hepatitis B surface antigen(HBsAg), creatinine kinase(CK), and estimated glomerular filtration rate (eGFR) were measured, safety was assessed. …”
Publicado 2020
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11563por Wang, Tao, Yang, Xianwei, Wang, Wanxiang, Chen, Tingyu, Kong, Junjie, Shen, Shu, Chen, Ying, Wei, Gengfu, Yu, Dinggang, Wang, Cong, Li, Minghao, Rui, Shaozhen, Luo, Biao, Wang, Wentao“…In the multivariate logistic analysis of the primary set, the independent factors for PCs were γ-glutamyl transferase (GGT), and surface area of hepatectomy, which were integrated into the nomogram combined with sarcopenia score. …”
Publicado 2020
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11564por Lai, Jinliang, Ji, Guanglin, Zhou, Yuqiao, Chen, Jincai, Zhou, Min, Mo, Jianwen, Zheng, Tiansheng“…Histologic changes in cartilaginous endplate chondrocytes were observed using hematoxylin and eosin (H&E) staining, transmission electron microscopy (TEM), and terminal deoxyribonucleotidyl transferase (TdT)-mediated dUTP nick-end labeling. RESULTS: Radiographic findings suggested a significantly decreased cervical physiological curvature in the forward flexed neck group over the 6-week follow-up; normal cervical curves were maintained in other groups. …”
Publicado 2021
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11565por Gao, Yanxia, Liu, Liwen, Li, Tiegang, Yuan, Ding, Wang, Yibo, Xu, Zhigao, Hou, Linlin, Zhang, Yan, Duan, Guoyu, Sun, Changhua, Che, Lu, Li, Sujuan, Sun, Pei, Li, Yi, Ren, Zhigang“…Eight factors, including age, ingestion volume, creatine kinase-MB [CK-MB], platelet [PLT], white blood cell [WBC], neutrophil counts [N], gamma-glutamyl transferase [GGT], and serum creatinine [Cr] were identified as independent risk indicators of in-hospital death events. …”
Publicado 2021
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11566por Niu, Meiyun, Yan, Haifeng, Xiong, Yuping, Zhang, Yueya, Zhang, Xinhua, Li, Yuan, da Silva, Jaime A. Teixeira, Ma, Guohua“…To understand the mechanism underlying the biosynthesis of santalols, in this study, we cloned two related genes involved in the mevalonate pathway in S. album coding for acetyl-CoA C-acetyl transferase (AACT) and 3-hydroxy-3-methyglutary-CoA synthase (HMGS). …”
Publicado 2021
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11567“…The expression of MMP8 and MMP9, chondrocyte differentiation markers collagen type II alpha 1 (COL2A1) and collagen type I alpha 1(COL1A1), and antiapoptotic protein BCL2 were detected using immunohistochemistry (IHC), and the number of apoptotic cells was detected by the transferase-mediated d-UTP nick-end-labeling (TUNEL) assay. …”
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11568“…Cell apoptosis was determined using terminal-deoxynucleotidyl transferase mediated nick end labeling (TUNEL) staining, and the expression of apoptotic proteins was examined using Western blot analysis. …”
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11569por Tian, Yu, Li, Peiwei, Xiao, Zhaohua, Zhou, Jie, Xue, Xia, Jiang, Ning, Peng, Chuanliang, Wu, Licun, Tian, Hui, Popper, Helmut, Poh, Mau-Ern, Marcucci, Fabrizio, Zhang, Chengke, Zhao, Xiaogang“…Cell proliferation and apoptosis were evaluated by immunohistochemistry (IHC) and terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) assay, respectively. …”
Publicado 2021
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11570por Wu, Mengjun, Yi, Dan, Zhang, Qian, Wu, Tao, Yu, Kui, Peng, Meng, Wang, Lei, Zhao, Di, Hou, Yongqing, Wu, Guoyao“…Puerarin decreased mRNA levels of glutathione S-transferase omega 2 but increased the levels of nuclear factor erythroid 2-related factor 2. …”
Publicado 2021
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11571por Ding, Li-Na, Cheng, Ya, Xu, Lu-Yao, Zhou, Le-Quan, Guan, Li, Liu, Hai-Mei, Zhang, Ya-Xing, Li, Run-Mei, Xu, Jin-Wen“…In addition, the phosphorylation and protein and mRNA expression of AMP-activated protein kinase (AMPK), peroxisome proliferator-activated receptor γ coactivator (PGC)-1α, and carnitine palmitoyl transferase (CPT)-1b in skeletal muscle were measured by Western blot analysis and qPCR. …”
Publicado 2021
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11572por Wang, Qinqin, Lu, Xuke, Chen, Xiugui, Malik, Waqar Afzal, Wang, Delong, Zhao, Lanjie, Wang, Junjuan, Wang, Shuai, Guo, Lixue, Cui, Ruifeng, Han, Mingge, Rui, Cun, Zhang, Yuexin, Fan, Yapeng, Chen, Chao, Ye, Wuwei“…According to gene functional annotation analysis, genes involved in reactive oxygen species (ROS) scavenging system including osmotic stress and ion toxicity were significantly up-regulated, especially GST (glutathione transferase). In addition, analysis for sulfur metabolism, results in to identification of two rate limiting enzymes [APR (Gh_D05G1637) and OASTL (Gh_A13G0863)] during synthesis of GSH from SO(4)(2−). …”
Publicado 2021
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11573por Firestone, Ross S., Feng, Mu, Basu, Indranil, Peregrina, Karina, Augenlicht, Leonard H., Schramm, Vern L.“…Generation of an MTDIA-resistant cell line in culture showed a four-fold amplification of the methionine adenosyl transferase (MAT2A) locus and expression of this enzyme. …”
Publicado 2021
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11574por Xue, Hong, Xie, Baosong, Xu, Nengluan, Li, Hongru, Chen, Qianshun, Xie, Weiping, Wang, Hong“…METHODS: Histopathological analysis of lung tissues from non-smokers and smokers with or without COPD was conducted using hematoxylin–eosin (H&E) staining, Van Gieson (VG) staining, and terminal transferase-mediated biotin dUTP nick end labeling (TUNEL). …”
Publicado 2021
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11575“…The lung function of each rat was measured, and then lung tissue structures, apoptosis, and collagen deposition were observed by hematoxylin-eosin staining, terminal deoxynucleotidyl transferase-mediated digoxigenin-dUTP nick-end labeling assay, and Masson’s staining, respectively. …”
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11576por Howell, Lawrence, Jenkins, Rosalind E., Lynch, Stephen, Duckworth, Carrie, Kevin Park, B., Goldring, Christopher“…While the final phenotype of differentiated organoids is distinct from liver tissue, the organoids contain multiple drug metabolizing and transporter proteins necessary for liver function and drug metabolism, such as cytochrome P450 3A, glutathione-S-transferase alpha and multidrug resistance protein 1A. …”
Publicado 2021
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11577“…The viability and apoptosis of transfected Huh-7 cells were, respectively, analyzed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and terminal deoxynucleotidyl transferase (TdT) dUTP Nick-End Labeling (TUNEL) assay. …”
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11578por Müller-Schüssele, Stefanie J., Bohle, Finja, Rossi, Jacopo, Trost, Paolo, Meyer, Andreas J., Zaffagnini, Mirko“…RESULTS: We analysed the genomes of nine representative model species from streptophyte algae to angiosperms and found that the antioxidant enzymes and redox proteins belonging to the plastid glutathione-dependent redox network are largely conserved, except for lambda- and the closely related iota-glutathione S-transferases. Focussing on glutathione-dependent redox modifications, we screened the literature for target thiols of S-glutathionylation, and found that 151 plastid proteins have been identified as glutathionylation targets, while the exact cysteine residue is only known for 17% (26 proteins), with one or multiple sites per protein, resulting in 37 known S-glutathionylation sites for plastids. …”
Publicado 2021
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11579por Zhang, Shaohong, Zhang, Mengxiao, Sun, Shuoshuo, Wei, Xiao, Chen, Yu, Zhou, Peng, Zheng, Rendong, Chen, Guofang, Liu, Chao“…Testicular cell apoptosis was assessed by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining. …”
Publicado 2021
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11580“…Crosstalk between H3K9me3 and DNA methylation was examined in cells transfected with siRNA of histone trimethyl-transferase, Suv39H1, or Dnmt1, exposed to high glucose. …”
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