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1161por Lee, Y. S., Choe, G. Y., Kim, Y. I., Park, S. H., Park, I. A., Lee, M. J., Jang, J. J.“…To evaluate the induction of preneoplastic hepatic foci in relation to natural killer cell (NK) activity, we sequentially analyzed glutathione S-transferase placental form positive (GST-P+) hepatocytes and NK activity during diethylnitrosamine (DEN) and phenobarbital (PB)-induced hepatocarcinogenesis in Sprague-Dawley rats. …”
Publicado 1999
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1162por Vintermist, Anna, Böhm, Stefanie, Sadeghifar, Fatemeh, Louvet, Emilie, Mansén, Anethe, Percipalle, Pergiorgio, Östlund Farrants, Ann-Kristin“…The association of the histone acetyl-transferases PCAF, p300 and GCN5 with the promoter is reduced in WSTF knock down cells, whereas the association of the histone acetyl-transferase MOF is retained. …”
Publicado 2011
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1163por de Oliveira Hiragi, Cássia, Miranda-Vilela, Ana Luisa, Rocha, Dulce Maria Sucena, de Oliveira, Silviene Fabiana, Hatagima, Ana, de Nazaré Klautau-Guimarães, Maria“…Antioxidants such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX1) reduce the oxidation rates in the organism. Gluthatione S-transferases (GSTs) play a vital role in phase 2 of biotransformation of many substances. …”
Publicado 2011
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1164por Rich, Tyvin A, Winter, Kathryn, Safran, Howard, Hoffman, John P, Erickson, Beth, Anne, Pramila R, Myerson, Robert J, Cline-Burkhardt, Vivian JM, Perez, Kimberly, Willett, Christopher“…The purpose of the randomized Phase II study by RTOG 0020 was to evaluate the addition of weekly low- dose gemcitabine with concurrent paclitaxel/RT and to evaluate the efficacy and safety of the farnesyl transferase inhibitor R115777 following chemoradiation. …”
Publicado 2012
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1165por Dan, Subhasish, Banerjee, Indranil, Roy, Himangshu, Roy, Shiuli, Jana, Tamoghna, Dan, SatrajitEnlace del recurso
Publicado 2012
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1166“…BACKGROUND: Recent studies on the association between Glutathione S-transferase T1 (GSTT1) polymorphism and risk of prostate cancer showed inconclusive results. …”
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1167por Huang, Sheng-xin, Wu, Fei-xiang, Luo, Min, Ma, Liang, Gao, Ke-feng, Li, Jian, Wu, Wen-juan, Huang, Shan, Yang, Qi, Liu, Ke, Zhao, Yin-nong, Li, Le-qun“…BACKGROUND: GSTP1, which is one major group of the glutathione S-transferase family, plays an important role in the metabolism of carcinogens and toxins, reducing damage of DNA as a suppressor of carcinogenesis. …”
Publicado 2013
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1168por Qiao, Zhe, Dang, Chengxue, Zhou, Bin, Li, Shaomin, Zhang, Wei, Jiang, Jiantao, Zhang, Jin, Kong, Ranran, Ma, Yuefeng“…The aim of this present study was to explore the expression and clinical significance of O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) and enzymatic O-linked glycosylation (O-GlcNAcation) through the addition of O-linked-β-N-acetylglucosamine in esophageal squamous cell carcinoma. …”
Publicado 2012
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1169“…Glutathione transferases (GSTs) are dimeric enzymes containing one active-site per monomer. …”
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1170por Kim, Ji Eun, Bunderson, Brett R., Croasdell, Amanda, Reed, Kent M., Coulombe, Roger A.“…We have demonstrated that such susceptibility is associated with the inability of hepatic glutathione S-transferases (GSTs) to detoxify the reactive electrophilic metabolite exo-AFB(1)-8,9-epoxide (AFBO). …”
Publicado 2013
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1171por Kitada, S, Yamada, S, Kuma, A, Ouchi, S, Tasaki, T, Nabeshima, A, Noguchi, H, Wang, K-Y, Shimajiri, S, Nakano, R, Izumi, H, Kohno, K, Matsumoto, T, Sasaguri, YEnlace del recurso
Publicado 2013
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1172“…The introduction of non-natural amino acids at the N-terminus of peptides/proteins using leucyl/phenylalanyl-tRNA-protein transferase (L/F-transferase) is a useful technique for protein engineering. …”
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1173por Chen, I-Hsuan, Chiu, Meng-Hsuen, Cheng, Shun-Fang, Hsu, Yau-Heiu, Tsai, Ching-Hsiu“…One of the plant glutathione S-transferase (GST) genes, NbGSTU4, responds as an upregulated gene in Nicotiana benthamiana post BaMV infection. …”
Publicado 2013
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1174“…To evaluate the relationship between glutathione-S-transferases polymorphisms and hypermethylation of these genes and the risk of prostate cancer BCR, we carried out a meta-analysis of the published studies. …”
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1175por Wu, Wenzhe, Wang, Zhaowei, Xia, Hongjie, Liu, Yongxiang, Qiu, Yang, Liu, Yujie, Hu, Yuanyang, Zhou, Xi“…Moreover, we found that FHV protein A also possesses a terminal nucleotidyl transferase (TNTase) activity, which was able to restore the nucleotide loss at the 3′-end initiation site of RNA template to rescue RNA synthesis initiation in vitro, and may function as a rescue and protection mechanism to protect the 3′ initiation site, and ensure the efficiency and accuracy of viral RNA synthesis. …”
Publicado 2014
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1176“…Cytochrome 8b1 (CYP8B1), aldehyde dehydrogenase 2 (Aldh2), and thiosulfate transferase (TST) were all significantly stimulated. …”
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1177por Shi, Hai-Yan, Li, Zheng-Hong, Zhang, Yu-Xing, Chen, Liang, Xiang, Di-Ying, Zhang, Yu-Feng“…Two genes encoding putative glutathione S-transferase proteins were isolated from pear (Pyrus pyrifolia) and designated PpGST1 and PpGST2. …”
Publicado 2014
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1178por Olling, Alexandra, Hüls, Corinna, Goy, Sebastian, Müller, Mirco, Krooss, Simon, Rudolf, Isa, Tatge, Helma, Gerhard, Ralf“…We hypothesized that the C-terminally-located combined repetitive oligopeptides (CROPs) interact with the N-terminal part of the toxin, thereby preventing autoproteolysis. Glutathione-S-transferase (GST) pull-down assays and microscale thermophoresis confirmed binding between the CROPs and the glucosyltransferase (TcdA(1–542)) or intermediate (TcdA(1102–1847)) domain of TcdA, respectively. …”
Publicado 2014
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1179por Lao, Xianjun, Peng, Qiliu, Lu, Yu, Li, Shan, Qin, Xue, Chen, Zhiping, Chen, JunqiangEnlace del recurso
Publicado 2014
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1180por Zhang, Hongyan, Wu, Xuwei, Xiao, Yi, Chen, Mei, Li, Zhidong, Wei, Xing, Tang, Kaifa“…BACKGROUND: Our objective is to investigate the genetic polymorphisms of the glutathione S-transferase M1 and T1 genes (GSTM1 and GSTT1) and evaluate oxidative damage in patients with non-small lung cancer (N-SCLC). …”
Publicado 2014
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