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12001por Rotimi, Oluwakemi A., Rotimi, Solomon O., Goodrich, Jaclyn M., Adelani, Isaacson B., Agbonihale, Emmanuel, Talabi, Gbemisola“…Mitochondria and cytosolic fractions were obtained from the liver after which lipids (cholesterol, triacylglycerols) were determined in the mitochondria while biomarkers of oxidative stress (glutathione, glutathione transferase (GST), glutathione peroxidase (GPx), glutathione reductase, nitric oxide (NO), malonaldehyde (MDA), thioredoxin reductase (TR), and superoxide dismutase (SOD) were determined spectrophotometrically in the mitochondria and cytosolic fractions. …”
Publicado 2019
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12002por Itkonen, Harri M, Urbanucci, Alfonso, Martin, Sara ES, Khan, Aziz, Mathelier, Anthony, Thiede, Bernd, Walker, Suzanne, Mills, Ian G“…O-GlcNAc transferase (OGT) is overexpressed in aggressive prostate cancer. …”
Publicado 2019
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12003por Scapini, Gustavo, Rasslan, Roberto, Cayuela, Natalie Chaves, Goes, Miguel Angelo, Koike, Marcia Kiyomi, Utiyama, Edivaldo Massazo, de Souza Montero, Edna Frasson, Rasslan, Samir“…A malondialdehyde (MDA) assay was performed to evaluate oxidative stress, and histochemical analyses (terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling [TUNEL], Bcl-2 and Bax) were conducted to evaluate kidney apoptosis. …”
Publicado 2019
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12004SAT-354 Characterization of Cell Death Induced by SOAT1 Inhibition in Adrenocortical Carcinoma Cellspor Weigand, Isabel, Schreiner, Jochen, Roehrig, Florian, Hoefner, Kerstin, Kendl, Sabine, Fassnacht, Martin, Sbiera, Silviu, Kroiss, Matthias“…We have found that mitotane inhibits Sterol-O-Acyl transferase 1 (SOAT1) which leads to depletion of cholesterol esters and increase of free cholesterol in the ACC cell line NCI-H295. …”
Publicado 2019
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12005por Kwon, Young Dai, Ko, Kyung Ok, Lim, Jae Woo, Cheon, Eun Jung, Song, Young Hwa, Yoon, Jung Min“…Obese children with fibrosis had higher levels of AST (73.57 ± 56.00 vs. 39.86 ± 31.93 IU/L; P = 0.009), ALT (132.47 ± 113.88 vs. 48.66 ± 51.29 IU/L; P = 0.001), and gamma-glutamyl transferase (106.67 ± 69.31 vs. 28.80 ± 24.26 IU/L; P = 0.042) compared to obese children without fibrosis. …”
Publicado 2019
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12006“…Apoptosis of MIN6 cells was detected by a terminal deoxynucleotidyl transferase-mediated deoxyuridinetriphosphate nick end labeling assay and western blot analysis of apoptotic proteins. …”
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12007por Meng, Wei, Xie, Binhui, Yang, Qing, Jia, Changchang, Tang, Hui, Zhang, Xiaomei, Zhang, Yi, Zhang, Jianwen, Li, Heping, Fu, Binsheng“…MTT assay, colony formation assay, terminal deoxynucleotidyl transferase nick end labeling assay and In vivo xenograft assay were used to determine the effect of MCM3 on radioresistance. …”
Publicado 2019
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12008por Xie, Yun-Kai, Zhou, Xin, Yuan, Hong-Tao, Qiu, Jie, Xin, Dan-Qing, Chu, Xi-Li, Wang, Da-Chuan, Wang, Zhen“…Neuronal apoptosis in the prefrontal cortex was detected by terminal deoxyribonucleotidyl transferase-mediated biotin-16-dUTP nick-end labeling assay. …”
Publicado 2019
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12009por Ansari, Mohd Nazam, Ganaie, Majid A., Rehman, Najeeb Ur, Alharthy, Khalid M., Khan, Tajdar H., Imam, Faisal, Ansari, Mushtaq A., Al-Harbi, Naif O., Jan, Basit L., Sheikh, Ishfaq A., Hamad, Abubaker M.“…Cardiotoxicity induced by Cd also resulted in enhanced expression of non-phosphorylated and phosphorylated form of NF-κB p65 and decreased expression of glutathione-S-transferase (GST) and NQO1 which were found reversed with ROF treatments, comparable to normal control group. …”
Publicado 2019
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12010por Kim, Mi-Young, Kruger, Annie J., Jeong, Ju-Yeon, Kim, Jaehee, Shin, Phil kyung, Kim, Sun Young, Cho, Joo Young, Hahm, Ki Baik, Hong, Sung Pyo“…CMG002 induced G0/G1 cell cycle arrest and enhanced apoptotic cell death in AGS and NUGC3 cells, particularly EBV-infected cells compared with mock-infected cells, as confirmed by flow cytometric analyses and TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) assays. The combination of CMG002 plus CQ synergistically increased apoptotic cell death in EBV-infected GC cell lines when compared with CMG002 alone (P < 0.05). …”
Publicado 2019
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12011“…This is probably caused by a secreted benzoic acid/salicylic acid methyl transferase from the pathogen (PbBSMT), which was one of the highest expressed pathogen genes in gall tissue. …”
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12012por Zhao, Fang, Su, Jing-Fen, Lun, Shu-Min, Hou, Yong-Jie, Duan, Li-Juan, Wang, Neng-Chao, Shen, Fang-Fang, Zhang, Yao-Wen, Gao, Zhao-Wei, Li, Jing, Du, Xian-Juan, Zhou, Fu-You“…No association was observed between CYP1A1 and CYP2E1. The glutathione S-transferase mu 1 (GSTM1) null genotype decreased EC risk (OR=0.510). …”
Publicado 2019
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12013“…Masson’s trichrome staining was used to determine the micro-fibrotic area to indicate the severity of myocardial loss. Terminal transferase uridine triphosphate nick end labeling staining was used to detect apoptotic cardiomyocytes. …”
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12014por Román-Anguiano, Nadia Giovanna, Correa, Francisco, Cano-Martínez, Agustina, de la Peña-Díaz, Aurora, Zazueta, Cecilia“…DNA integrity was evaluated by DNA laddering visualized on an agarose gel and by Terminal deoxynucleotidyl transferase dUTP Nick-End Labeling assay. Activities of caspase-3, caspase-8, caspase-9 and calpain-1 were evaluated spectrophotometrically and the content of caspase-3 and calpain-1 by western blot. …”
Publicado 2019
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12015por Munemoto, Masayoshi, Mukaisho, Ken‐ichi, Miyashita, Tomoharu, Oyama, Katsunobu, Haba, Yusuke, Okamoto, Koichi, Kinoshita, Jun, Ninomiya, Itasu, Fushida, Sachio, Taniura, Naoko, Sugihara, Hiroyuki, Fujimura, Takashi“…Expression of O‐GlcNAc transferase (OGT) increased considerably in both ESCC and EAC compared with nonneoplastic squamous epithelium. …”
Publicado 2019
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12016por Malila, Yuwares, Thanatsang, Krittaporn, Arayamethakorn, Sopacha, Uengwetwanit, Tanaporn, Srimarut, Yanee, Petracci, Massimiliano, Strasburg, Gale M., Rungrassamee, Wanilada, Visessanguan, Wonnop“…The muscle-specific mu-2 isoform of glutathione S-transferases (GSTM2) was up-regulated in the abnormal samples, particularly in the heavy groups. …”
Publicado 2019
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12017por Sudhakar, Padhmanand, Jacomin, Anne-Claire, Hautefort, Isabelle, Samavedam, Siva, Fatemian, Koorosh, Ari, Eszter, Gul, Leila, Demeter, Amanda, Jones, Emily, Korcsmaros, Tamas, Nezis, Ioannis P.“…Abbreviations: ATG5: autophagy related 5; CALCOCO2/NDP52: calcium binding and coiled-coil domain 2; GST: glutathione S-transferase; LIR: MAP1LC3/LC3-interacting region; MAP1LC3/LC3: microtubule associated protein 1 light chain 3 alpha; OMV: outer membrane vesicles; SQSTM1/p62: sequestosome 1; SCV: Salmonella containing vesicle; TECPR1: tectonin beta-propeller repeat containing 1; YhjJ: hypothetical zinc-protease.…”
Publicado 2019
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12018por Kang, Wen, Cheng, Yue, Zhou, Fang, Wang, Long, Zhong, Liang, Li, Hai Tao, Wang, Xi, Dang, Song, Wang, Xin“…Apoptosis rates were determined using terminal deoxynucleotidyl transferase dUTP nick end labeling staining. Ras homolog family member A (RhoA) and Rho-associated protein kinase 1 (ROCK1) protein levels were assessed using western blotting. …”
Publicado 2019
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12019“…Due to the misuse of chemical pesticides, small green leafhoppers (Empoasca onukii Matsuda) have developed resistance to pesticides, thereby posing a serious problem to the tea industry. Glutathione S-transferases (GSTs) are an important family of enzymes that are involved in pesticide resistance in Empoasca onukii Matsuda. …”
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12020por Fogarty, Conor E., Zhao, Min, McManus, Donald P., Duke, Mary G., Cummins, Scott F., Wang, Tianfang“…Susceptible B. glabrata several proteins correlated with immunity and anti-inflammation, such as glutathione S-transferase and zinc metalloproteinase, and S. mansoni sporocyst presence. …”
Publicado 2019
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