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12121“…Apoptotic cells were detected using the transferase-mediated dUTP nick end labelling (TUNEL) assay. …”
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12122por Ma, Kaige, Xing, Shan, Luan, Yan, Zhang, Chenglin, Liu, Yingfei, Fei, Yulang, Zhang, Zhichao, Liu, Yong, Chen, Xinlin“…The role of Gpc4/LRP1 on toxic/physical Aβ-induced effects was evaluated using the JC-1 kit, terminal deoxynucleotidyl transferase dUPT nick end labeling, and western blotting. …”
Publicado 2021
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12123por Stotz, Sophie, Bowden, Gregory D., Cotton, Jonathan M., Pichler, Bernd J., Maurer, Andreas“…SNAPTag is a high-affinity protein tag used in a variety of biochemical research areas and based on the suicide DNA repair enzyme O(6)-methylguanine methyl transferase (MGMT). Its ligands are well suited for reporter gene imaging as the benzyl guanine core scaffold can be derivatized with fluorescent or radiolabeled moieties for various applications. …”
Publicado 2021
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12124por Sieroń, Karolina, Knapik, Katarzyna, Onik, Grzegorz, Romuk, Ewa, Birkner, Ewa, Kwiatek, Sebastian, Sieroń, Aleksander“…After 28 consecutive days of the experiment, the following pro- and antioxidative markers were assessed in the gastrointestinal tract homogenates: superoxide dismutase (SOD) and its two isoenzymes (Mn-SOD, Cu,Zn-SOD) catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), total antioxidative capacity (TAC), total oxidative status (TOS), and malondialdehyde (MDA). …”
Publicado 2021
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12125por He, Zhangya, Li, Xiaomin, Yang, Hexiang, Wu, Pei, Wang, Shanshan, Cao, Dan, Guo, Xiaoxiao, Xu, Zhangrui, Gao, Jiayi, Zhang, Wanyu, Luo, Xiaoqin“…The levels of other indicators of liver health, such as gamma-glutamyl transferase, alkaline phosphatase, total bilirubin, and direct bilirubin were decreased after the intervention but comparable among the three groups and so did the parameters of glucose metabolism, such as fasting insulin, fasting glucose, and homeostasis model assessment for insulin resistance. …”
Publicado 2021
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12126“…The changes in the rats' cognitive function were evaluated using the Morris water maze, the hippocampal histopathological changes were observed via hematoxylin-eosin (H&E) staining, and the apoptosis rate of neuronal cells was detected through terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) staining. …”
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12127por Perdices, Lorena, Fuentes-Broto, Lorena, Segura, Francisco, Cavero, Ana, Orduna-Hospital, Elvira, Insa-Sánchez, Gema, Sánchez-Cano, Ana Isabel, Fernández-Sánchez, Laura, Cuenca, Nicolás, Pinilla, Isabel“…No differences were observed in visual acuity, nitrate levels, nitrite levels or glutathione S-transferase activity. In conclusion, EGCG not only reduced the loss of visual function in P23H rats but also improved the levels of antioxidant enzymes and reduced oxidative damage. …”
Publicado 2021
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12128por Zhang, Deshuang, Xie, Dongke, He, Na, Wang, Xiaoling, Dong, Wenbin, Lei, Xiaoping“…There was no significant difference in serum alanine transferase (ALT), aspartate transaminase (AST), creatinine (Cr), or direct bilirubin (DBIL) levels between the two groups. …”
Publicado 2021
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12129por Menkem, Brice, Vemo, Bertin Narcisse, Tsambou, Megnimeza Martine Astride, Fonou, Tadiesse Lavoisier, Dongmo, Nguedia Arius Baulland, Boufack, Judith Laure, Chongsi, Margaret Mary Momo, Kenfack, Augustave“…Results revealed a significant decrease (p < 0.05) of serum levels of creatinine, urea, alanine, and aspartate amino transferases in guinea pigs treated with cadmium chloride and EEPLM compared to the negative control group (Cd). …”
Publicado 2021
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12130“…The apoptosis rate of cerebral cells in the ischemic area was examined by TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) staining, and the expression of Bcl-2, Bax, and caspase-3 was observed by western blot. …”
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12131“…The metabolic processes associated with ammonia detoxification and antioxidant stress were also affected by starter diet supplementation, with proteins, microsomal glutathione S-transferase 3 (MGST3, FC = 2.37) and IDH1, linked to the biosynthesis of glutamate and glutathione metabolism pathway being upregulated in the group with starter diet supplementation. …”
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12132“…The primary measured outcomes included the neural functional deficit score (NFS), infarct volume (IV), brain water content, cell viability, apoptotic cells, terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick end labeling (TUNEL)-positive cells, B-cell lymphoma-2 (Bcl-2) level and tumor necrosis factor-α (TNF-α) level. …”
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12133por Poradowski, Dominik, Janus, Izabela, Chrószcz, Aleksander, Obmińska-Mrukowicz, Bożena“…The apoptosis assessment was carried out using TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) assay. EC(50) values, computed for risedronate sodium and meloxicam cytotoxicity, showed comparable effects against the canine OS cell line in similar concentration of both drugs. …”
Publicado 2021
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12134“…Cell Counting Kit-8, enzyme-linked immunosorbent assay, terminal deoxynucleotidyl-transferase-mediated dUTP nick end labeling and western blotting experiments were used to detect cell activity, lactate dehydrogenase release, apoptosis and apoptosis-related proteins (Bcl-2, Bax, Cleaved caspase-3 and Cleaved caspase-9), respectively. …”
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12135por He, Siyi, He, Shengdong, Yang, Yongxiang, Li, Bin, Gao, Liang, Xie, Qingyun, Zhang, Lin“…According to the results of lactate dehydrogenase (LDH), creatine kinase (CK), creatine kinase isoenzymes (CK-MB), and aspartate amino transferase (AST), patients were divided into myocardial injury group and normal group. …”
Publicado 2021
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12136por Thai, Phung N., Miller, Charles V., King, M. Todd, Schaefer, Saul, Veech, Richard L., Chiamvimonvat, Nipavan, Bers, Donald M., Dedkova, Elena N.“…A KE diet increased expression of mitochondrial succinyl‐CoA:3‐oxoacid‐CoA transferase and restored decreased expression of mitochondrial β‐hydroxybutyrate dehydrogenase, key enzymes in cardiac ketone metabolism. …”
Publicado 2021
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12137por Yang, Lu, Bi, Liping, Jin, Lulu, Wang, Yuming, Li, Yuting, Li, Zixuan, He, Wenju, Cui, Huantian, Miao, Jing, Wang, Li“…Terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling assay (TUNEL) staining demonstrated that geniposide could reduce the apoptosis of hepatocytes. …”
Publicado 2021
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12138por Mengeste, Abel M., Lund, Jenny, Katare, Parmeshwar, Ghobadi, Roya, Bakke, Hege G., Lunde, Per Kristian, Eide, Lars, Mahony, Gavin O’, Göpel, Sven, Peng, Xiao-Rong, Kase, Eili Tranheim, Thoresen, G. Hege, Rustan, Arild C.“…The increased OA metabolism was accompanied by enhanced mRNA-expression of carnitine palmitoyl transferase (CPT) 1B, pyruvate dehydrogenase kinase (PDK) 4, as well as increased AMP-activated protein kinase (AMPK)(Thr172) phosphorylation. …”
Publicado 2021
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12139por Lampignano, Luisa, Donghia, Rossella, Griseta, Chiara, Lagravinese, Gianvito, Sciarra, Sabrina, Zupo, Roberta, Castellana, Fabio, Bortone, Ilaria, Guerra, Vito, Tirelli, Sarah, De Nucci, Sara, Tatoli, Rossella, Lozupone, Madia, Sborgia, Giancarlo, Leo, Antonio, De Pergola, Giovanni, Giannelli, Gianluigi, Panza, Francesco, Sardone, Rodolfo“…Subjects with dementia were older [effect size (ES): −0.89, 95% CI: −1.07 to −0.70], had a lower level of education (ES:0.88, 95% CI:0.69–1.06), higher levels of gamma-glutamyl transferase (ES: −0.21, 95% CI: −0.39 to −0.03), lower levels of total cholesterol (ES: −0.24, 95% CI: −0.42 to −0.06) and low-density lipoprotein cholesterol (ES: −0.20, 95% CI: −0.38 to 0.02), and a higher FLI (ES: −0.22, 95% CI: −0.39 to −0.04). …”
Publicado 2021
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12140por Moreira, Daniel C., Carvajalino-Fernández, Juan M., Navas, Carlos A., de Carvalho, José E., Hermes-Lima, Marcelo“…When data for P. diplolister and P. cristiceps were assembled and analyzed, significant effects of species were detected on the activities of metabolic enzymes (citrate synthase, isocitric dehydrogenase, malic enzyme, and creatine kinase) and antioxidant enzymes (catalase, glutathione peroxidase and glutathione transferase), as well as on GSSG/tGSH ratio. Such effects might underlie the physiological and behavioral differences between these two species that share the same microhabitat and survival strategy (i.e., to estivate) during the dry season. …”
Publicado 2021
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