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12321“…In addition, miR-124-3p, TRAF3 and CREB expression in hepatocytes was altered to identify their roles in modulating the levels of glutathione transferase (GST), aspartate aminotransferase (AST) and alanine aminotransferase (ALT), and inflammation-related factors and hepatocyte apoptosis by ELISA and flow cytometry respectively. …”
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12322por Yao, Xin, Cao, Yujie, Lu, Li, Xu, Yuanxia, Chen, Hao, Liu, Chuanqi, Chen, Dianyi, Wang, Kexue, Xu, Jingxiang, Fang, Runqi, Xia, Hui, Li, Jiangyan, Fang, Qiang, Tao, Zhiyong“…Apoptosis was assessed by terminal deoxynucleotidyl transferase (TdT) dUTP nick-end labeling (TUNEL) staining, and the expression of apoptosis-related proteins including Bax, Bcl-2, caspase-9, and cleaved caspase-3 was detected by western blot and immunohistochemistry, respectively. …”
Publicado 2022
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12323por Zeng, Juanzi, Wu, Heming, Liu, Donghua, Li, Liang, Li, Jiaquan, Wang, Qiuming, Ye, Min, Huang, Qingyan, Yu, Zhikang, Zhang, Jinfeng“…BACKGROUND: The link between glutathione S-transferase P1 (GSTP1) c.313A > G polymorphism and chemotherapy-related adverse events remains controversial. …”
Publicado 2022
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12324por Liu, Zhi, He, He, Dai, Yuzhao, Yang, Lidan, Liao, Shenling, An, Zhenmei, Li, Shuangqing“…RESULTS: After adjusting for age, sex, and body mass index (BMI), serum alanine transaminase (ALT), aspartate transaminase (AST), AST/ALT (A/A), fasting plasma glucose (FPG), cystatin C (Cys-C), uric acid (URIC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), non-HDL-C, LDL-C/HDL-C, non-HDL-C/HDL-C, TG/HDL-C, TC/HDL-C, TyG, and TyG-BMI were risk factors for MAFLD. …”
Publicado 2022
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12325por Shuang, Ou, Zhou, Jianmin, Cai, Zijun, Liao, Longteng, Wang, Yuehua, Wang, Wenyu, Xu, Meng“…Functional assays including immunofluorescence (IF), colony formation, transferase-mediated dUTP nick-end labeling (TUNEL) as well as transwell assays were utilized to test the cell biological process caused by the genes. …”
Publicado 2022
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12326“…Cell counting kit-8 (CCK-8), 5-ethynyl-2’-deoxyuridine (EdU), terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL), transwell assays and western blot analysis of epithelial-mesenchymal transition (EMT) markers were conducted to evaluate cell proliferation, apoptosis, migration, and EMT process. …”
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12327por Lv, Shangbin, Chen, Xiaodong, Chen, Yu, Gong, Daoyin, Mao, Gang, Shen, Caifei, Xia, Ting, Cheng, Jing, Luo, Zhaoliang, Cheng, Yu, Li, Weihong, Zeng, Jinhao“…Apoptosis was detected in rat gastric mucosal cells by terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling staining. …”
Publicado 2022
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12328por Sotomi, Yohei, Sato, Taiki, Hikoso, Shungo, Komukai, Sho, Oeun, Bolrathanak, Kitamura, Tetsuhisa, Nakatani, Daisaku, Mizuno, Hiroya, Okada, Katsuki, Dohi, Tomoharu, Sunaga, Akihiro, Kida, Hirota, Seo, Masahiro, Yano, Masamichi, Hayashi, Takaharu, Nakagawa, Akito, Nakagawa, Yusuke, Tamaki, Shunsuke, Ohtani, Tomohito, Yasumura, Yoshio, Yamada, Takahisa, Sakata, Yasushi“…The 16‐variable model consists of C‐reactive protein, creatinine, gamma‐glutamyl transferase, brain natriuretic peptide, white blood cells, systolic blood pressure, fasting blood sugar, triglyceride, clinical scenario classification, infection‐triggered acute decompensated HF, estimated glomerular filtration rate, platelets, neutrophils, GWTG‐HF (Get With The Guidelines‐Heart Failure) risk score, chronic kidney disease, and CONUT (Controlling Nutritional Status) score. …”
Publicado 2022
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12329por Beltrame, Lucas Cafferati, Zamparette, Caetana Paes, Feltrin, Clarissa, da Cunha, Caroline Ribeiro, Coltro, Elisa Pires, Athayde, Gabriel Saldanha da Silva, Filho, Vilmar Benetti, Tápparo, Deisi Cristina, Monteiro, Jamir, Kich, Jalusa Deon, Palmeiro, Jussara Kasuko, Wagner, Glauber, Fongaro, Gislaine, Zárate-Bladés, Carlos Rodrigo, Sincero, Thaís Cristine Marques“…In addition, PCR reactions were performed to confirm the presence or absence of seven different beta-lactamase family genes and five phosphoethanolamine transferase gene variants clinically relevant. Our findings based on the identification of resistance genes at the mechanism level showed a prevalence of alteration of the drug target (72.3%) profile, followed by drug inactivation (17.5%) and drug efflux (10.1%). …”
Publicado 2022
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12330por Valle, Antonio, Soto, Zamira, Muhamadali, Howbeer, Hollywood, Katherine A., Xu, Yun, Lloyd, Jonathan R., Goodacre, Royston, Cantero, Domingo, Cabrera, Gema, Bolivar, Jorge“…The main genetic engineering strategies to achieve this aim involve the mutation of succinate dehydrogenase (sdhA) gene and also those responsible for acetate synthesis including acetate kinase, phosphate acetyl transferase and pyruvate oxidase encoded by ackA, pta and pox genes respectively in the ΔsdhAΔack-ptaΔpox (M4) mutant. …”
Publicado 2022
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12331por Kim, Soo Yeon, Ko, Saebom, Kang, Hyunook, Kim, Man Jin, Moon, Jangsup, Lim, Byung Chan, Kim, Ki Joong, Choi, Murim, Choi, Hee-Jung, Chae, Jong-Hee“…BACKGROUND: Aminoacyl tRNA transferases play an essential role in protein biosynthesis, and variants of these enzymes result in various human diseases. …”
Publicado 2022
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12332por Okimatsu, Sho, Furuya, Takeo, Miura, Masataka, Shiratani, Yuki, Yunde, Atsushi, Inoue, Takaki, Maki, Satoshi, Ohtori, Seiji“…There was no significant difference between the immediate decompression group and the sub-acute decompression group. TUNEL (transferase-mediated dUTP nick end labeling) staining showed significantly fewer positive cells in both decompression groups compared to the non-decompression group. …”
Publicado 2022
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12333por Zheng, Liang, Xu, Hongbiao, Zheng, Fufu, Lai, Yuanhui, Li, Jie, Lv, Weiming, Hu, Zuojun, Wang, Wenjian“…Cell apoptosis was evaluated by terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL). RESULTS: The cells were treated with ox-LDL for 12 h and 36 h, which were considered to represent early and advanced stages of atherogenesis for this study. …”
Publicado 2022
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12334por van Broekhoven, Amber, Mohammadnia, Niekbachsh, Silvis, Max J. M., Los, Jonathan, Fiolet, Aernoud T. L., Opstal, Tjerk S. J., Mosterd, Arend, Eikelboom, John W., Nidorf, Stefan M., Budgeon, Charley A., Byrnes, Elizabeth, Bax, Willem A., Tijssen, Jan G. P., de Kleijn, Dominique P. V., Thompson, Peter L., El Messaoudi, Saloua, Cornel, Jan H.“…METHODS: Blood samples drawn from 1776 participants at the close-out visit of the LoDoCo2 trial were used to measure markers of renal function (creatinine, blood urea nitrogen [BUN]), liver function (alanine aminotransferase [ALT], γ-glutamyl transferase [GGT], bilirubin and albumin), and CK. Renal and liver function as well as hyperCKemia (elevated CK) were categorized to the degree of elevation biomarkers as mild, mild/moderate, moderate/severe, and marked elevations. …”
Publicado 2022
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12335por Volonté, Mariano, Traverso, Lucila, Estivalis, Jose Manuel Latorre, Almeida, Francisca Cunha, Ons, Sheila“…Three major gene families are involved in xenobiotic detoxification in insects: the cytochromes P450 (CYPs), carboxyl/cholinesterases (CCEs), and glutathione transferases (GSTs). Here we perform a comparative analysis on the complement of these gene superfamilies across five hemipteran species; four heteropterans (the pentatomid plant feeders Nezara viridula and Halyomorpha halys; the hematophagous Cimex lectularius, Cimicidae, and Rhodnius prolixus, Reduviidae), and one Auchenorrhyncha plant feeder (Nilaparvata lugens). …”
Publicado 2022
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12336“…Gallbladder wall thickness (GBWT), indexes of blood routine examination, including white blood cell (WBC), alkaline phosphatase (ALP), the percentage of neutrophil, alanine transaminase (ALT), aspartate aminotransferase (AST), fibrinogen (FIB), gamma-glutamyl transferase, prothrombin time and total bilirubin were evaluated. …”
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12337por Kang, Dongru, Khan, Muhammad Ayoub, Song, Pan, Liu, Yvru, Wu, Yifei, Ai, Penghui, Li, Zhongai, Wang, Zicheng“…In addition, 5-azaC treatment resulted in the differential expression of multiple DNA methylation transferases, which led to the differential expression of many genes. …”
Publicado 2023
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12338por Gobut, Huseyin, Kucuk, Aysegul, Şengel, Necmiye, Arslan, Mustafa, Ozdemir, Cagrı, Mortas, Tulay, Kasapbası, Esat, Kurtipek, Omer, Kavutcu, Mustafa“…Malondialdehyde (MDA) levels, catalase (CAT), glutathione-s-transferase (GST), and arylesterase (ARE) enzyme activities were measured in the tissue samples. …”
Publicado 2023
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12339por Feng, Yao, Zhou, Ying-Hui, Zhao, Jie, Su, Xiao-Lin, Chen, Ning-Xin, Zhao, Ya-Qiong, Ye, Qin, Hu, Jing, Ou-Yang, Ze-Yue, Zhong, Meng-Mei, Yang, Yi-Fan, Han, Peng-Ju, Guo, Yue, Feng, Yun-Zhi“…Background: Glutathione S-transferase kappa 1 (GSTK1) is critical in sarcoma and breast cancer (BRCA) development. …”
Publicado 2023
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12340por Henao, Laura, Zade, Ramin Shirali Hossein, Restrepo, Silvia, Husserl, Johana, Abeel, Thomas“…Lastly, the presence of a putative mono-ADP-ribosyl transferase, homologous to the virulence factor scabin, was confirmed in Streptomyces sp. …”
Publicado 2023
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