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1221“…However, the effect of interaction between PFASs and glutathione S-transferase (GST) T1/M1 genotype on AD remains unclear. …”
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1222“…BACKGROUND: There are several meta-analyses on the genetic relationship between the rs1695 polymorphism within the GSTP1 (glutathione S-transferase pi 1) gene and the risk of different SCC (squamous cell carcinoma) diseases, such as ESCC (oesophageal SCC), HNSCC (head and neck SCC), LSCC (lung SCC), and SSCC (skin SCC). …”
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1223por Tchouakui, Magellan, Chiang, Mu-Chun, Ndo, Cyrille, Kuicheu, Carine K., Amvongo-Adjia, Nathalie, Wondji, Murielle J., Tchoupo, Micareme, Kusimo, Michael O., Riveron, Jacob M., Wondji, Charles S.“…Here, we investigated the association between a marker of glutathione S-transferase mediated metabolic resistance and Plasmodium infection in field population of Anopheles funestus s.s. in comparison to the A296S-RDL target site mutation. …”
Publicado 2019
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1224por Sun, Yuesheng, Pan, Jianghua, Tong, Xiaochun, Chen, Ende, Yan, Wangxin, Wu, Mengpei, Qu, Qiang, Qu, Jian“…Background: The role of glutathione s-transferase genes (GSTP1, GSTM1 and GSTT1) variants and the GSTP1 expression level on chemotherapy efficacy of gastrointestinal cancer (GIC) patients were inconsistent. …”
Publicado 2019
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1225por Leppilahti, Jussi, Majuri, Marja-Leena, Sorsa, Timo, Hirvonen, Ari, Piirilä, Päivi“…Di-isocyanate inhalation has been reported to induce oxidative stress via reactive oxygen and nitrogen species leading to tissue injury. Glutathione transferases (GSTs) and N-acetyltransferases (NATs) are detoxifying enzymes whose general function is to inactivate electrophilic substances. …”
Publicado 2019
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1226por Derbyshire, Mark C., Gohari, Amir Mirzadi, Mehrabi, Rahim, Kilaru, Sreedhar, Steinberg, Gero, Ali, Solaf, Bailey, Andy, Hammond-Kosack, Kim, Kema, Gert H. J., Rudd, Jason J.Enlace del recurso
Publicado 2019
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1227por Farahmand, Fatemeh, Ahmadi, Mitra, Khodadad, Ahmad, Najafi, Mehri, Fallahi, Gholamhossein, Motamed, Farzaneh, Movahedi, Masoud, Aghamohammadi, Asghar, Rezaei, Nima, Javaherizadeh, HazhirEnlace del recurso
Publicado 2019
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1228por Rao, Muhammad Junaid, Xu, Yuantao, Huang, Yue, Tang, Xiaomei, Deng, Xiuxin, Xu, Qiang“…To better understand the underlying mechanism, we designed experiments to overexpress a UDP-GLUCOSYL TRANSFERASE gene from sweet orange (Citrus sinensis) to evaluate its possible function in metabolism and response to stress. …”
Publicado 2019
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1229por Zhou, Jing-Ru, Bu, Dan-Ru, Zhao, Xian-Feng, Wu, Fei, Chen, Xue-Qiu, Shi, Heng-Zhi, Yao, Chao-Qun, Du, Ai-Fang, Yang, Yi“…Our in vitro assay demonstrated that Hc-HRG-2 is a heme-binding protein with glutathione S-transferase activity and heme had a significant effect on its enzymatic activity when a model substrate 1-chloro-2, 4-dinitrobenzene (CDNB) was used. …”
Publicado 2020
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1230por Jeong, Dae-Eun, Lee, Yujin, Ham, Seokjin, Lee, Dongyeop, Kwon, Sujeong, Park, Hae-Eun H., Hwang, Sun-Young, Yoo, Joo-Yeon, Roh, Tae-Young, Lee, Seung-Jae V.“…The oligosaccharyl transferase (OST) protein complex mediates the N-linked glycosylation of substrate proteins in the endoplasmic reticulum (ER), which regulates stability, activity, and localization of its substrates. …”
Publicado 2020
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1231por Batsios, Georgios, Najac, Chloé, Cao, Peng, Viswanath, Pavithra, Subramani, Elavarasan, Saito, Yutaro, Gillespie, Anne Marie, Yoshihara, Hikari A. I., Larson, Peder, Sando, Shinsuke, Ronen, Sabrina M.“…Glutathione (GSH) is often upregulated in cancer, where it serves to mitigate oxidative stress. γ-glutamyl-transferase (GGT) is a key enzyme in GSH homeostasis, and compared to normal brain its expression is elevated in tumors, including in primary glioblastoma. …”
Publicado 2020
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1232por Wang, Qiming, Fang, Peining, He, Rui, Li, Mengqi, Yu, Haisheng, Zhou, Li, Yi, Yu, Wang, Fubing, Rong, Yuan, Zhang, Yi, Chen, Aidong, Peng, Nanfang, Lin, Yong, Lu, Mengji, Zhu, Ying, Peng, Guoping, Rao, Liqun, Liu, Shi“…In this study, we demonstrated an essential function of the hexosamine biosynthesis pathway (HBP)–associated O-linked β-N-acetylglucosamine (O-GlcNAc) signaling in influenza A virus (IAV)–induced cytokine storm. O-GlcNAc transferase (OGT), a key enzyme for protein O-GlcNAcylation, mediated IAV-induced cytokine production. …”
Publicado 2020
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1233por Chen, Haihua, Gan, Qixin, Yang, Congying, Peng, Xiongqun, Qin, Jiao, Qiu, Sisi, Jiang, Yanzhi, Tu, Sha, He, Ying, Li, Shenglan, Yang, Huixiang, Tao, Lijian, Peng, YuEnlace del recurso
Publicado 2020
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1234por Tan, Junkai, Zhang, Xiaoguang, Li, Danli, Liu, Guo, Wang, Yun, Zhang, Daren, Wang, Xizhen, Tian, Wenhong, Dong, Xiaoyan, Zhou, Liang, Zhu, Xianjun, Liu, Xuyang, Fan, Ning“…In this study, we explored whether exoenzyme C3 transferase (C3)-based gene therapy could protect retinas in an ischemia/reperfusion (I/R) injury rat model. …”
Publicado 2020
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1235por Fujii, Hideki, Doi, Haruna, Ko, Tetsuhisa, Fukuma, Taito, Kadono, Toru, Asaeda, Kohei, Kobayashi, Reo, Nakano, Takahiro, Doi, Toshifumi, Nakatsugawa, Yoshikazu, Yamada, Shinya, Nishimura, Takeshi, Tomatsuri, Naoya, Sato, Hideki, Okuyama, Yusuke, Kimura, Hiroyuki, Kishimoto, Etsuko, Nakabe, Nami, Shima, Takatomo“…Some individuals frequently present elevated gamma-glutamyl transferase (GGT) levels without fatty liver ultrasound images and other abnormal liver enzymes levels. …”
Publicado 2020
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1236por Lee, Da Young, Han, Kyungdo, Yu, Ji Hee, Park, Sanghyun, Heo, Jee-In, Seo, Ji A., Kim, Nam Hoon, Yoo, Hye Jin, Kim, Sin Gon, Kim, Seon Mee, Choi, Kyung Mook, Baik, Sei Hyun, Park, Yong Gyu, Kim, Nan HeeEnlace del recurso
Publicado 2020
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1237por Loi, Elena Maria, Weiss, Matjaž, Pajk, Stane, Gobec, Martina, Tomašič, Tihomir, Pieters, Roland J., Anderluh, Marko“…O-GlcNAcylation is an essential post-translational modification that occurs on nuclear and cytoplasmic proteins, regulating their function in response to cellular stress and altered nutrient availability. O-GlcNAc transferase (OGT) is the enzyme that catalyzes this reaction and represents a potential therapeutic target, whose biological role is still not fully understood. …”
Publicado 2020
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1238por Xiao, Binyi, Peng, Jianhong, Tang, Jinghua, Deng, Yuxiang, Zhao, Yujie, Wu, Xiaojun, Ding, Peirong, Lin, Junzhong, Pan, ZhizhongEnlace del recurso
Publicado 2020
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1239por Fujitani, Naoki, Yoneda, Akihiro, Takahashi, Motoko, Takasawa, Akira, Aoyama, Tomoyuki, Miyazaki, TadaakiEnlace del recurso
Publicado 2020
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1240“…Bark beetles have a corresponding defense mechanism for degrading toxic compounds, and glutathione S-transferases (GSTs) can catalyze the binding of endogenous substances that reduce glutathione (GSH) to various harmful electrophilic substrates, increasing their solubility and facilitating their excretion from cells. …”
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