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1241“…The ether linkages of the resulting MPHPV enantiomers are cleaved by stereoselective glutathione (GSH) S-transferases (GSTs) encoded by ligF, ligE, and ligP, generating (βR/βS)-α-glutathionyl-β-hydroxypropiovanillone (GS-HPV) and guaiacol. …”
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1242por Ince, Volkan, Carr, Brian I, Bag, Harika Gozukara, Ersan, Veysel, Usta, Sertac, Koc, Cemalettin, Gonultas, Fatih, Sarici, Baris Kemal, Karakas, Serdar, Kutluturk, Koray, Baskiran, Adil, Yilmaz, SezaiEnlace del recurso
Publicado 2020
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1243por Hasan, Md. Soyib, Singh, Vishal, Islam, Shiful, Islam, Md. Sifatul, Ahsan, Raju, Kaundal, Amita, Islam, Tahmina, Ghosh, Ajit“…Glutathione transferases (GSTs) constitute an ancient, ubiquitous, multi-functional antioxidant enzyme superfamily that has great importance on cellular detoxification against abiotic and biotic stresses as well as plant development and growth. …”
Publicado 2021
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1244“…In this report, we extend our previous characterization of Dictyostelium discoideum glutathione S-transferase (DdGST) enzymes that are expressed in the eukaryotic model organism. …”
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1245por Trabjerg, Michael Sloth, Andersen, Dennis Christian, Huntjens, Pam, Oklinski, Kirsten Egelund, Bolther, Luise, Hald, Jonas Laugård, Baisgaard, Amalie Elton, Mørk, Kasper, Warming, Nikolaj, Kullab, Ulla Bismark, Kroese, Lona John, Pritchard, Colin Eliot Jason, Huijbers, Ivo Johan, Nieland, John Dirk Vestergaard“…Specifically, we report that the activity of carnitine palmitoyl transferase 1 (CPT1) lipid metabolism is associated with disease progression. …”
Publicado 2021
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1246“…Oxidative stress is a key factor contributing to the development of diabetes complications. Glutathione S-transferases (GSTs) protect against products of oxidative stress by conjugating glutathione to electrophilic substrates, producing compounds that are generally less reactive and more soluble. …”
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1247por Lian, Ling, Lin, Yuelong, Wei, Yidong, He, Wei, Cai, Qiuhua, Huang, Wei, Zheng, Yanmei, Xu, Huibin, Wang, Fuxiang, Zhu, Yongsheng, Luo, Xi, Xie, Huaan, Zhang, Jianfu“…In particular, the most enriched pathway “glutathione (GSH) metabolism”, which mainly contains GSH S-transferase (GST), was identified in transgenic rice. …”
Publicado 2021
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1248“…However, TMZ-induced N6-meG sites are efficiently repaired and mediated by the DNA repair protein O(6)-methylguanine-DNA methyl-transferase (MGMT), leading to TMZ resistance. KLF15, a member of the Kruppel-like factors family, mainly functions as transcription factor and potential suppressor gene by inhibiting proliferation, migration, and inducing apoptosis. …”
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1249por Brown, Alistair S., Owen, Jeremy G., Jung, James, Baker, Edward N., Ackerley, David F.“…A recently-validated and underexplored drug target in Mycobacterium tuberculosis is PptT, an essential phosphopantetheinyl transferase (PPTase) that plays a critical role in activating enzymes for both primary and secondary metabolism. …”
Publicado 2021
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1250por Mao, Xue-Ling, Li, Zi-Han, Huang, Meng-Han, Wang, Jin-Tao, Zhou, Jing-Bo, Li, Qing-Run, Xu, Hong, Wang, Xi-Jin, Zhou, Xiao-LongEnlace del recurso
Publicado 2021
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1251por Kishimoto, Naoki, Okano, Ryosuke, Akita, Ayano, Miura, Satoshi, Irie, Ayaka, Takamune, Nobutoki, Misumi, Shogo“…RESULTS: Here, we show that arginyl-tRNA-protein transferase 1 (ATE1) plays an important role in the uncoating process by governing the optimal core stability. …”
Publicado 2021
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1252por Ugalde, José Manuel, Lamig, Liliana, Herrera-Vásquez, Ariel, Fuchs, Philippe, Homagk, Maria, Kopriva, Stanislav, Müller-Schüssele, Stefanie J, Holuigue, Loreto, Meyer, Andreas J“…Plant glutathione S-transferases (GSTs) are glutathione-dependent enzymes with versatile functions, mainly related to detoxification of electrophilic xenobiotics and peroxides. …”
Publicado 2021
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1253por Padi, Neo, Akumadu, Blessing Oluebube, Faerch, Olga, Aloke, Chinyere, Meyer, Vanessa, Achilonu, Ikechukwu“…Glutathione transferases (GSTs) are the main detoxification enzymes in schistosomes. …”
Publicado 2021
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1254por Xu, Bangtian, Tong, Tingting, Wang, Xin, Liu, Fang, Zhang, Xiang, Hu, Xiaolei, Li, Xinpeng, Yang, Xiaolan, Liao, Fei“…The linking of ethacrynic acid with ethylenediamine and 1,4-butanediamine gave EDEA and BDEA, respectively, as membrane-permeable divalent pro-inhibitors of glutathione S-transferase (GST). Their divalent glutathione conjugates showed subnanomolar inhibition and divalence-binding to GSTmu (GSTM) (PDB: 5HWL) at ∼0.35 min(−1). …”
Publicado 2022
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1255“…In this study, we identified 53 glutathione S-transferase genes (PavGSTs) from sweet cherry and found that PavGST1 expression was well correlated with anthocyanin accumulation in cultivars with different fruit skin colors. …”
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1256“…BACKGROUND: Cytochrome P450 (CYP) and glutathione S transferases (GSTs) are important biotransforming enzymes responsible for detoxification of anticancer drugs and carcinogens. …”
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1257por Aubee, Joseph I, Adigun, Alexandria, Branch, Kirsten R, Conyer, Ava C, Olusanya, Olufolakemi, Williams, Kinlyn, Thompson, Karl M“…OBJECTIVES/GOALS: MiaA is a highly conserved prenyl transferase that catalyzes synthesis of the i6A37 tRNA modification in E. coli. …”
Publicado 2022
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1258por Xue, Lei, Huang, Xiaorong, Zhang, Zehuang, Lin, Qihua, Zhong, Qiuzhen, Zhao, Yun, Gao, Zhongshan, Xu, Changjie“…It has been known that in plants anthocyanins are synthesized in the cytoplasmic surface of the endoplasmic reticulum and subsequently transported into the vacuole for storage, and glutathione S-transferases (GSTs) have been verified to be involved in this process. …”
Publicado 2022
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1259por Rahbar, Mohammad H., Samms-Vaughan, Maureen, Kim, Sori, Saroukhani, Sepideh, Bressler, Jan, Hessabi, Manouchehr, Grove, Megan L., Shakspeare-Pellington, Sydonnie, Loveland, Katherine A.“…Glutathione S-transferases (GST) are involved in the detoxification of exogenous chemicals including lead (Pb). …”
Publicado 2022
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1260por Stan, Marius, Botnarciuc, Vladimir, Suceveanu, Andra-Iulia, Mazilu, Laura, Costea, Daniel Ovidiu, Suceveanu, Adrian-Paul, Serban, Dragos, Tudor, Corneliu, Mitroi, Anca, Brinzan, Costel, Voinea, Felix“…The aim of the present study was to evaluate the diagnostic value of glutathione-S-transferase gene P1 (GST-P1) in patients that fall within the ‘grey area’ of the prostate-specific antigen (PSA) values. …”
Publicado 2022
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