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1261por Wang, Xuewen, Xu, Dafen, Chen, Bing, Huang, Dandan, Li, Zhijun, Sui, Yuxia, Lin, Fei, Yao, Hong, Li, Huang Yuan, Lin, Xinhua“…DLL-mediated antitumor immune effects were reversed by overexpression of the N6-methyladenosine (m6A) transferase Mettl3/Mettl14. Mechanistically, DLL upregulated the expression of Stat1 and Irf1 and the secretion of cytokines by inhibiting Mettl3 and Mettl14 in lung cancer cells. …”
Publicado 2022
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1262por Piaggi, Simona, Lorenzini, Evelina, Pratesi, Federico, Migliorini, Paola, Pompella, Alfonso, Bruschi, Fabrizio, Corti, Alessandro“…Glutathione S-transferase omega-1 (GSTO1-1) is a cytosolic enzyme involved in the modulation of critical inflammatory pathways as well as in cancer progression. …”
Publicado 2022
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1263“…The present study is aimed at discovering the in-depth pathogenesis of IPF, exploring the role of adiponectin/carnitine palmityl transferase 1A- (APN/CPT1A-) mediated fatty acid metabolism during the development of IPF, and excavating its potential mechanism. …”
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1264por Nkeck, Jan René, Ida, Chemgne Marie, Koe, Valerie Ndobo, Ndam, Antonin Wilson Ndjitoyap, Jessica, Yondo Ndedi Claudine, Manuella, Eko Ondoa, Charelle, Boukeu Yonta, Corine, Zouague Zalbi, Andrée, Ntyam Abena, Amazia, Falmata, Nkeck, Jériel Pascal, Samba, Esther Astrid Mbono, Moor, Vicky Jocelyne Ama“…OBJECTIVE: The usefulness of gamma glutamyl transferase (GGT) as biomarker of cardiovascular risk (CVR) remains unexplored in sub-Saharan Africans. …”
Publicado 2022
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1265“…BACKGROUND: Gamma-glutamyl transferase (GGT) and high-density lipoprotein cholesterol (HDL-C) have been proven to be valuable predictors of type 2 diabetes mellitus (T2DM). …”
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1266“…The PKSs cannot be functional unless their acyl carrier proteins (ACPs) are phosphopantetheinylated by phosphopantetheinyl transferases (PPTases). Gra-ORF32 was identified as an in-cluster PPTase dedicated for granaticin biosynthesis in Streptomyces vietnamensis and the Arg- and Pro-rich N terminus was found to be crucial for catalytic activity. …”
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1268por Jarerattanachat, Viwan, Boonarkart, Chompunuch, Hannongbua, Supa, Auewarakul, Prasert, Ardkhean, Ruchuta“…We aim to identify potential inhibitors against Dengue NS5 Methyl transferase from small molecular compounds found in Ginseng and Notoginseng. …”
Publicado 2022
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1269por Orlewska, Katarzyna, Klusek, Justyna, Głuszek, Stanisław, Klusek, Jolanta, Witczak, Bartosz, Wawszczak, Monika, Madej, Łukasz, Marzec, Michał Tomasz, Orlewska, Ewa“…GST (glutathione S-transferases) are capable of influencing glucose homeostasis, probably through regulation of the response to oxidant stress. …”
Publicado 2023
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1270por Xu, Tianqi, Yu, Xi, Zhou, Shenjun, Wu, Yiwen, Deng, Xinpeng, Wu, Yuefei, Wang, Shiyi, Gao, Xiang, Nie, Sheng, Zhou, Chenhui, Sun, Jie, Huang, Yi“…Objective: We performed a case-control study to investigate the correlation between DNA methylation and mRNA expression of the glutathione S-transferase alpha 4 (GSTA4) gene and the risk of intracranial aneurysm (IA) in the Chinese Han population. …”
Publicado 2023
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1271por Haijer, Floris W., Van Vliet, Cornelis B., Brusse-Keizer, Marjolein G. J., Van der Palen, Job A. M., Kerbert-Dreteler, Marjo J., Kolkman, Jeroen J.Enlace del recurso
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1272“…Cytochrome P450 (CYP) monooxygenases and glutathione S-transferases (GST) are enzymes that catalyse chemical modifications of a range of organic compounds. …”
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1274por Li, Xingang, Pang, Yuanting, Zhong, Yiwang, Cai, Zhandong, Ma, Qibin, Wen, Ke, Nian, Hai“…In this study, we identified a tau-like glutathione transferase family gene from soybean named GmGSTU23. …”
Publicado 2023
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1276
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1277por Kreuder, Amanda J., Breuer, Ryan M., Wiley, Caitlin, Dohlman, Tyler, Smith, Joseph S., McKeen, Lauren“…METHODS: Retrospective study to assess serum immunoglobulin (IgG) concentrations via turbidimetric immunoassay (TI), gamma‐glutamyl transferase (GGT), serum total protein (TP), and single radial immunodiffusion (RID; reference standard). …”
Publicado 2023
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1278“…There was also no significant association between intraindividual variability and hepatitis B surface antigen, anti-hepatitis C virus (anti-HCV), glutathione S-transferase (GST) M1, or GSTT1 status. In conclusion, we found substantial intraindividual variability in the AFB1 exposure (as determined by AFB1-albumin adducts) in Taiwan, which was probably more likely related to dietary or other environmental influences rather than to endogenous factors (e.g., hepatitis B/C viral infection or GST M1/T1 genetic status).…”
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1279“…BACKGROUND: Glutathione S-transferases (GSTs) are known to abolish or reduce the activities of intracellular enzymes that help detoxify environmental carcinogens, such as those found in tobacco smoke. …”
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1280por Liu, Ai-Lin, Lu, Wen-Qing, Wang, Zeng-Zhen, Chen, Wei-Hong, Lu, Wen-Hong, Yuan, Jing, Nan, Pei-Hong, Sun, Jian-Ya, Zou, Ya-Lin, Zhou, Li-Hong, Zhang, Chi, Wu, Tang-Chun“…To investigate associations among occupational exposure to coke oven emissions (COEs), oxidative stress, cytogenotoxic effects, change in the metabolizing enzyme glutathione S-transferase (GST), and internal levels of polycyclic aromatic hydrocarbons (PAHs) in coke oven workers, we recruited 47 male coke oven workers and 31 male control subjects from a coke oven plant in northern China. …”
Publicado 2006
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