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12921por Li, Wenjie, Yao, Min, Wang, Ruonan, Shi, Yun, Hou, Lianguo, Hou, Ziyuan, Lian, Kaoqi, Zhang, Nan, Wang, Yaqi, Li, Weiwei, Wang, Wei, Jiang, Lingling“…Cardiac ATP levels were analyzed using a commercially available kit. mRNA levels of glucose transporter 4 (GLUT4), fatty acid binding protein 3 (FABP3), palmitoyl transferase 1α (CPT-1α), acyl-CoA oxidase 1 (AOX1), D-bifunctional protein (DBP), 3-ketoacyl-CoA thiolase A (THLA), uncoupling protein (UCP) 2 and UCP3 were investigated by quantitative reverse-transcription polymerase chain reaction. …”
Publicado 2018
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12922por Awodele, O., Badru, W. A., Busari, A. A., Kale, O. E., Ajayi, T. B., Udeh, R. O., Emeka, P. M.“…Therapeutic doses of CGV elevated reduced glutathione, superoxide dismutase, catalase and glutathione S-transferase, although, this was exceeded by supra-therapeutic doses and more in females than male rats. …”
Publicado 2018
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12923“…The high-temperature stimulus mainly induced the expression of glutathione S-transferase, heat shock protein, ascorbate peroxidase, manganese superoxide dismutase, ubiquitin-related protein, lhcSR, rubisco activase, serine/threonine protein kinase 2, adenylate kinase, Ca(2+)-dependent protein kinase (CDPK), disease resistance protein EDS1, metacaspase type II, NDPK2a, 26S proteasome regulatory subunit, ubiquinone oxidoreductase, ATP synthase subunit, SnRK2s, and cytochrome P450. …”
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12924por Yang, Guiyan, Gao, Xiangqian, Ma, Kaiheng, Li, Dapei, Jia, Caixia, Zhai, Meizhi, Xu, Zhenggang“…Compared to the wild type (WT) Arabidopsis, S3, S7, and S8 exhibited enhanced seed germination rate, fresh weight accumulation, and activities of catalase (CAT), peroxidase (POD), superoxide dismutase (SOD) and glutathione-S-transferase (GST) under HT stress. In contrast, the Evans blue staining, electrolyte leakage (EL) rates, hydrogen dioxide (H(2)O(2)) and malondialdehyde (MDA) content of transgenic seedlings were all lower than those of WT exposed to HT stress. …”
Publicado 2018
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12925por Andresini, Oriella, Rossi, Marianna Nicoletta, Matteini, Francesca, Petrai, Stefano, Santini, Tiziana, Maione, Rossella“…Moreover, chromatin immunoprecipitation assays after Kcnq1ot1 depletion demonstrated that the LncRNA is required for the accumulation of H3K27me3, a chromatin modification catalyzed by the histone-methyl-transferase EZH2, at the maternal p57(kip2) intragenic region. …”
Publicado 2019
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12926por Leong, Cherng-Shii, Vythilingam, Indra, Liew, Jonathan Wee-Kent, Wong, Meng-Li, Wan-Yusoff, Wan Sulaiman, Lau, Yee-Ling“…The results of synergism tests and biochemical assays indicated that the mixed functions of oxidases and glutathione S-transferases contributed to the DDT and pyrethroid resistance observed in the present study. …”
Publicado 2019
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12927por Hakkim, Faruck L., Bakshi, Hamid A., Khan, Shabia, Nasef, Mohamad, Farzand, Rabia, Sam, Smitha, Rashan, Luay, Al-Baloshi, Mohammed S., Abdo Hasson, Sidgi Syed Anwar, Jabri, Ali Al, McCarron, Paul A., Tambuwala, Murtaza M.“…Pre treatment with FEO (250 and 500 mg/kg body weight) for seven days retained hematology (complete blood count), biochemical parameters (AST, ALT, ALK, total bilirubin, total protein, glucose, albumin/globulin ratio, cholesterol and triglyceride), and the level of phase I and II drug metabolizing enzymes (cytochrome P450, cytochromeb5, glutathione-S-transferase) which were obstructed by the administration of acetaminophen. …”
Publicado 2019
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12928“…Recently we reported that androgens through both the extra-nuclear and nuclear pathways inhibit the expression and activity of Ezh2, (a histone methyl-transferase involved in gene repression mark, H3K27me3) to induce different genes that are imperative for ovarian function. …”
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12929por Gubbi, Sriram, Mathias, Priyanka, Palaiodimos, Leonidas, Schubart, Ulrich, Hulkower, Raphael“…Background: Metanephrines (MTN), which include normetanephrine (NMN) and metanephrine (MN), are metabolites of catecholamines formed by o-methylation of norepinephrine and epinephrine respectively, by the enzyme catechol-o-methyl transferase present in its most active form in the chromaffin cell derived tumors, namely pheochromocytoma and paraganglioma (PPGL). …”
Publicado 2019
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12930por Butt, Nazish, Reema, Sehrish, Ali Khan, M, Abbasi, Amanullah, Butt, Sehrish, Khoso, Mohammad M, Akbar, Ali, Haleem, Farhan, Mahesar, Ghulam B, Fahad, Anoshia, Qureshi, Talha“…The mean alanine transaminase (ALT), aspartate aminotransferase (AST), and gamma-glutamyl transferase (GGT) levels at presentation were 41.89 ± 46.23 IU/l, 68.57 ± 83.62 IU/l, and 54.52 ± 77.57 IU/l, respectively. …”
Publicado 2019
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12931por Jain, Ram B.“…Data (N = 9523) for US adults for the years 2003–2014 from National Health and Nutrition Examination Survey were analyzed to estimate variabilities in concentrations associated with liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphate (APH), and γ-glutamyl transferase (GGT) across the stages of GF and to assess variabilities in associations that perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) may have with these enzymes across the stages of GF. …”
Publicado 2019
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12932por Ma, Hui, Lam, Ping Kuen, Tong, Cindy See Wai, Lo, Kin Ki Yan, Wong, George Kwok Chu, Poon, Wai Sang“…Compared with normoxic mesenchymal stem cells and traumatic brain injury only groups, there was significantly (p < 0.05) less neuronal death in both the hippocampus and penumbral regions in sections treated with hypoxic mesenchymal stem cells as determined by Cresyl violet and terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling staining respectively. …”
Publicado 2019
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12933por Xiong, Guangbing, Liu, Chang, Yang, Gang, Feng, Mengyu, Xu, Jianwei, Zhao, Fangyu, You, Lei, Zhou, Li, Zheng, Lianfang, Hu, Ya, Wang, Xiaowo, Zhang, Taiping, Zhao, Yupei“…We then constructed a chemoresistance-related lncRNA-associated ceRNA network and proposed that lncRNA Homo sapiens glutathione S-transferase mu 3, transcript variant 2 and noncoding RNA (GSTM3TV2; NCBI Reference Sequence: NR_024537.1) might act as a key ceRNA to enhance chemoresistance by upregulating L-type amino acid transporter 2 (LAT2) and oxidized low-density lipoprotein receptor 1(OLR1) in pancreatic cancer. …”
Publicado 2019
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12934“…Pneumococcus teichoic acid (TA) and lipoteichoic acid (LTA) have repeating units with α-GalNAc-(1→3)β-GalNAc decorated with phosphorylcholine (PC) at the O-6 positions. Two PC transferases, LicD1 and LicD2, mediate the attachment of PC to GalNAc residues while phosphorylcholine esterase (Pce) removes PCs attached to the terminal GalNAcs. …”
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12935por Bhavnani, Sujata M, Trang, Michael, George, Darryl R, Liolios, Kathryn, McGovern, Paul C, Friedrich, Lawrence, Steenbergen, Judith N, Rubino, Christopher M, Tzanis, Evan, Ambrose, Paul G, Hammel, Jeffrey P“…RESULTS: The final model, developed using data from 327 patients with PK, included increased prior cumulative AUC among males, increased baseline gamma-glutamyl transferase, and study (ABSSSI, PO only) as factors predictive of increased ALT (P < 0.0001). …”
Publicado 2019
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12936por Chen, Mao-Sheng, Zhao, Mei-Li, Wang, Gui-Juan, He, Hui-Ying, Bai, Xue, Pan, Bang-Zhen, Fu, Qian-Tang, Tao, Yan-Bin, Tang, Ming-Yong, Martínez-Herrera, Jorge, Xu, Zeng-Fu“…Among them, Jatropha ADENOSINE KINASE 2 (JcADK2), ADENINE PHOSPHORIBOSYL TRANSFERASE 1 (JcAPT1), CYTOKININ OXIDASE 3 (JcCKX3), ISOPENTENYLTRANSFERASE 5 (JcIPT5), LONELY GUY 3 (JcLOG3) and JcLOG5 may participate in cytokinin metabolic pathway in Jatropha. …”
Publicado 2019
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12937“…The number of terminal deoxynucleotidyl transferase-mediated nucleotide nick-end labeling-positive apoptotic hepatocytes in LPS/D-Gal-exposed mice also reduced. …”
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12938por Bai, Jie, Luo, Lei, Liu, Shuang, Liang, Chen, Bai, Li, Chen, Yu, Zheng, Sujun, Duan, Zhongping“…The current study aimed to investigate the effects of uridine diphospho-glucuronosyl transferase 1A1 (UGT1A1) and/or solute carrier organic anion transporter family member 1B (SLCO1B) polymorphic variants and their combined effects on mild unconjugated hyperbilirubinemia in Chinese adults. …”
Publicado 2019
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12939por Kabisch, Stefan, Meyer, Nina Marie Tosca, Honsek, Caroline, Gerbracht, Christiana, Dambeck, Ulrike, Kemper, Margrit, Osterhoff, Martin A., Birkenfeld, Andreas L., Arafat, Ayman M., Weickert, Martin O., Pfeiffer, Andreas F.H.“…Within the OBESE stratum, leukocyte count and gamma-glutamyl transferase (GGT) levels decreased more in the fibre group compared with placebo (adjusted for change in body weight). …”
Publicado 2019
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12940“…Specifically, the up-regulated genes were enriched in acute phase response (P < 0.01), pyruvate metabolic process (P < 0.01) and proton-acceptors (P ≪ 0.001), indicating the liver’s response to feed induced acidosis at the transcriptome level. Twelve transferase activity related genes had significant correlation with rumen microbial rRNA expression changes. …”
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