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1321por Mørkholt, Anne Skøttrup, Wiborg, Ove, Nieland, Jette G. K., Nielsen, Søren, Nieland, John Dirk“…Mitochondrial carnitine palmitoyl transferase 1a (CPT1a) is a key molecule involved in lipid metabolism and mutations in CPT1a causing reduced function is hypothesized to have a protective role in the development of depression. …”
Publicado 2017
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1322“…OBJECTIVES: Glutathione‐S‐transferases (GSTs) detoxify reactive xenobiotics, and defective GST gene polymorphisms increase cancer risk in humans. …”
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1323“…Specimens were stained with hematoxylin and eosin, along with a terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling (TUNEL) assay, to highlight the degree of irreversible cellular injury. …”
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1324por Abdul Kayum, Md., Nath, Ujjal Kumar, Park, Jong-In, Biswas, Manosh Kumar, Choi, Eung Kyoo, Song, Jae-Young, Kim, Hoy-Taek, Nou, Ill-Sup“…Plant growth and development can be adversely affected by cold stress, limiting productivity. The glutathione S-transferase (GST) family comprises important detoxifying enzymes, which play major roles in biotic and abiotic stress responses by reducing the oxidative damage caused by reactive oxygen species. …”
Publicado 2018
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1325por He, Feng, Liu, Changyu, Zhang, Ruijie, Hao, Zhipeng, Li, Yangkai, Zhang, Ni, Zheng, Liang“…BACKGROUND: Glutathione-S-Transferase T1 (GSTT1) null genotype has been shown to be associated with the risk of esophageal cancer. …”
Publicado 2018
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1326por Kontur, Wayne S., Bingman, Craig A., Olmsted, Charles N., Wassarman, Douglas R., Ulbrich, Arne, Gall, Daniel L., Smith, Robert W., Yusko, Larissa M., Fox, Brian G., Noguera, Daniel R., Coon, Joshua J., Donohue, Timothy J.“…We found that the Nu-class glutathione S-transferase NaGST(Nu) is the only enzyme needed to remove glutathione from both (R)- and (S)-GS-HPV in N. aromaticivorans. …”
Publicado 2018
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1327“…Aromatic hydrocarbons in smoke, including benzo[n]pyrene, first require metabolic activation by Phase I enzymes, cytochrome P450, to their ultimate forms, and these activated forms are then subjected to detoxification by Phase II enzymes, especially glutathione S‐transferases. Thus, genetically determined susceptibility to lung cancer may depend on the metabolic balance between Phase I and Phase II enzymes. …”
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1328por Kasagi, Noriko, Gomyo, Yoshihito, Shirai, Hiroyuki, Tsujitani, Shunichi, Ito, Hisao“…We have examined the occurrence of apoptotic cell death in formalin‐fixed, paraffin‐embedded human gastric carcinoma specimens by the terminal deoxynucleotidyl transferase (TdT)‐mediated dUTP‐biotin nick end labeling (TUNEL) method. …”
Publicado 1994
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1329por Nakae, Dai, Denda, Ayumi, Kobayashi, Yozo, Akai, Hiroyuki, Kishida, Hideki, Tsujiuchi, Toshifumi, Konishi, Yoichi, Suzuki, Toshiya, Muramatsu, Masami“…Hepatocarcinogenesis initiated with N‐nitrosodiethylamine (DEN) and that initiated by feeding of a choline‐deficient, l‐amino acid‐defined (CDAA) diet were compared in transgenic male Wistar rats harboring a rat glutathione S‐transferase placental form (GST‐P) gene (GST‐P‐Tg rats) and non‐transgenic (N‐Tg) rats. …”
Publicado 1998
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1330“…Using the placental form of glutathione S‐transferase (GST‐P) as a marker of carcinogen‐initiated hepatocytes, we investigated how a choline‐deficient (CD) diet and BR931, a carcinogenic hypolipidemic agent, modify populations of single GST‐P‐positive hepatocytes. …”
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1331por Howlett, Robert, Read, Nicholas, Varghese, Anpu, Kershaw, Charles, Hancock, Y., Smith, Margaret C. M.Enlace del recurso
Publicado 2018
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1332por Flint, Mike, Chatterjee, Payel, Lin, David L., McMullan, Laura K., Shrivastava-Ranjan, Punya, Bergeron, Éric, Lo, Michael K., Welch, Stephen R., Nichol, Stuart T., Tai, Andrew W., Spiropoulou, Christina F.“…We identify GNPTAB, which encodes the α and β subunits of N-acetylglucosamine-1-phosphate transferase. We show that EBOV infection of a GNPTAB knockout cell line is impaired, and that this is reversed by reconstituting GNPTAB expression. …”
Publicado 2019
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1333por Kontur, Wayne S., Olmsted, Charles N., Yusko, Larissa M., Niles, Alyssa V., Walters, Kevin A., Beebe, Emily T., Vander Meulen, Kirk A., Karlen, Steven D., Gall, Daniel L., Noguera, Daniel R., Donohue, Timothy J.“…Sphingomonad bacteria use stereospecific glutathione S-transferases (GSTs) called β-etherases to cleave the β-aryl ether (β-O-4) bond, the most common bond between aromatic subunits in lignin. …”
Publicado 2019
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1334por Ouyang, Haomiao, Du, Ting, Zhou, Hui, Wilson, Iain B. H., Yang, Jinghua, Latgé, Jean-Paul, Jin, Cheng“…In this report the gene encoding A. fumigatus EtN-P transferase GPI7 was investigated. By deletion of the gpi7 gene, we evaluated the effects of EtN-P modification on the morphogenesis of A. fumigatus and localization of GPI proteins. …”
Publicado 2019
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1335“…It was thought that some pesticides used in agriculture could adversely affect the antioxidant enzyme system and the minimum inhibition values were studied. glutathione s-transferase (GST), an important antioxidant enzyme, catalyzes the conjugation of glutathione with toxic metabolites. …”
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1336por Hou, Yanhua, Qiao, Chenhui, Wang, Yifan, Wang, Yatong, Ren, Xiulian, Wei, Qifeng, Wang, Quanfu“…Glutathione S-transferases are one of the most important antioxidant enzymes to protect against oxidative damage induced by reactive oxygen species. …”
Publicado 2019
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1337por Tchouakui, Magellan, Fossog, Billy Tene, Ngannang, Brigitte Vanessa, Djonabaye, Doumani, Tchapga, Williams, Njiokou, Flobert, Wondji, Charles S.“…Here, we investigated the potential impact of the glutathione S-transferase L119F-GSTe2 resistance on the mating competitiveness of male Anopheles funestus, in Cameroon. …”
Publicado 2019
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1338por Weigand, Isabel, Altieri, Barbara, Ferreira, Amanda, Basile, Vittoria, Landwehr, Laura-Sophie, Ronchi, Cristina, Schreiner, Jochen, Megerle, Felix, Berruti, Alfredo, Canu, Letizia, Volante, Marco, Paiva, Isabel, Della Casa, Silvia, Sbiera, Silviu, Fassnacht, Martin, Fragoso, Maria, Terzolo, Massimo, Kroiss, Matthias“…We have previously discovered that mitotane is an inhibitor of sterol-O-Acyl transferase 1 (SOAT1) which leads to depletion of cholesterol esters, endoplasmic reticulum stress and cell death in the ACC cell line NCI-H295. …”
Publicado 2019
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1339por Islam, Shiful, Sajib, Saikat Das, Jui, Zakya Sultana, Arabia, Shatil, Islam, Tahmina, Ghosh, Ajit“…Glutathione S-transferases (GSTs) compose a family of multifunctional enzymes involved in the numerous aspects of regulating plant growth, development, and stress response. …”
Publicado 2019
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1340por Tan, Junkai, Wang, Xizhen, Cai, Suping, He, Fen, Zhang, Daren, Li, Dongkan, Zhu, Xianjun, Zhou, Liang, Fan, Ning, Liu, Xuyang“…We have demonstrated that the lentivirus-mediated exoenzyme C3 transferase (C3) expression in rat and monkey eyes induced relatively long-term IOP reduction. …”
Publicado 2019
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