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1381por Kumar, Gavish, Dagur, Pradeep Kumar, Singh, Prashant Kumar, Shankar, Hari, Yadav, Virendra S., Katoch, Vishwa M., Bajaj, Bharat, Gupta, Rajesh, Sengupta, Utpal, Joshi, Beenu“…In the present study an enzyme-linked immunosorbent assay was used to evaluate the diagnostic potential of an immuno-dominant 30/32-kDa mycolyl transferase complex (Ag85 complex) and Mycobacterium tuberculosis-specific proteins (ESAT-6 and CFP-10) of the RD1 region. …”
Publicado 2010
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1382por Minelli, Cosetta, Granell, Raquel, Newson, Roger, Rose-Zerilli, Matthew J, Torrent, Maties, Ring, Sue M, Holloway, John W, Shaheen, Seif O, Henderson, John A“…Background Oxidative stress is thought to be involved in the pathogenesis of asthma. Glutathione-S-transferase (GST) enzymes, which play an important role in antioxidant defences, may therefore influence asthma risk. …”
Publicado 2010
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1383por Park, Young-Min, Lee, Heon-Jeong, Kang, Seung-Gul, Choi, Jung-Eun, Cho, Jae-Hyuck, Kim, Leen“…The aims of this study was to assess the possible association between the oxidative stress related Glutathione S-Transferase genes (GST-M1, GST-T1, and GST-P1) variants and the olanzapine-induced weight gain in Korean schizophrenic patients. …”
Publicado 2010
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1384“…While it is widely believed that Rev1 plays a non-catalytic function in translesion synthesis, the role of its dCMP transferase activity remains uncertain. To determine the relevance of its catalytic function in translesion synthesis, we separated the Rev1 dCMP transferase activity from its non-catalytic function in yeast. …”
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1386por Linher-Melville, Katja, Zantinge, Stephanie, Sanli, Toran, Gerstein, Hertzel, Tsakiridis, Theodoros, Singh, Gurmit“…The current study examined breast cancer as a metabolic disease in the context of altered fatty acid catabolism by examining the effect of PRL on carnitine palmitoyl transferase 1 (CPT1), an enzyme that shuttles long-chain fatty acids into the mitochondrial matrix for β-oxidation. …”
Publicado 2011
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1387“…Lanp is a critical member of the protein complex inhibitor of histone acetyl transferase (INHAT), which prevents histone tail's acetylation, thus leading to transcriptional repression. …”
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1388por Suneetha, K. J., Nancy, K. Nirmala, Rajalekshmy, K. R., Rama, R., Sagar, T. G., Rajkumar, T.“…BACKGROUND: Polymorphisms in the drug-metabolizing enzymes are found to be associated with the inter-individual variation in response to a particular drug. Glutathione S-transferases (GSTs) are involved in the metabolism of several anticancer drugs, including alkylating agents, anthracyclines, and cyclophosphamides. …”
Publicado 2011
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1389“…OBJECTIVES: To study the epidemiology of Hepatitis B virus (HBV) and Hepatitis C virus (HCP) in a relatively new industrial community in Yanbu, and to find out whether any relationship exists between increased serum Alanine Transferase (ALT) and HBV infection. METHOD: A group of Saudi male workers (n=332) (mean age = 32 years) were screened for Hepatitis B core antibody (anti-HBc), Hepatitis B surface antigen (HBsAg), Hepatitis C virus antibody (anti-HCV), and Alanine Transferase (ALT) level and the results were correlated with age and marital status. …”
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1390“…We have demonstrated that the glutathione S-transferase M1 (GSTM1) null genotype could aggravate DEP-induced airway inflammation in human subjects. …”
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1391por Shafiee-Nick, Reza, Ghorbani, Ahmad, Vafaee Bagheri, Farzaneh, Rakhshandeh, Hassan“…Also, there was significant difference in the level of triglyceride (60 ± 9 versus 158 ± 37 mg/dl, P < 0.01), total cholesterol (55 ± 2 versus 97 ± 11 mg/dl, P < 0.01) and aspartate amino transferase activity (75 ± 12 versus 129 ± 18 U/L, P < 0.05) between treated rats and diabetic control group. …”
Publicado 2012
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1392por Weng, Jianfeng, Li, Bo, Liu, Changlin, Yang, Xiaoyan, Wang, Hongwei, Hao, Zhuanfang, Li, Mingshun, Zhang, Degui, Ci, Xiaoke, Li, Xinhai, Zhang, Shihuang“…ZmIPT2, which is expressed mainly in the basal transfer cell layer, endosperm, and embryo during maize kernel development, encodes an isopentenyl transferase (IPT) that is involved in CK biosynthesis. …”
Publicado 2013
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1393por Chen, Chang, Wu, Chuanhong, Lu, Xinhua, Yan, Zhiyong, Gao, Jian, Zhao, Hui, Li, Shaojing“…Glutathione S-transferase (GST) is the key enzyme in multidrug resistance (MDR) of tumour. …”
Publicado 2013
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1394“…The present study was carried out to investigate the effect of 28-homobrassinolide (28-HBL) on the protein content as well as activities of antioxidant enzymes viz., glutathione-s-transferase (GST) and polyphenol oxidase (PPO) in radish plants grown under Cadmium (Cd) and Mercury (Hg) metal stress. …”
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1395por Callier, Patrick, Calvel, Pierre, Matevossian, Armine, Makrythanasis, Periklis, Bernard, Pascal, Kurosaka, Hiroshi, Vannier, Anne, Thauvin-Robinet, Christel, Borel, Christelle, Mazaud-Guittot, Séverine, Rolland, Antoine, Desdoits-Lethimonier, Christèle, Guipponi, Michel, Zimmermann, Céline, Stévant, Isabelle, Kuhne, Françoise, Conne, Béatrice, Santoni, Federico, Lambert, Sandy, Huet, Frederic, Mugneret, Francine, Jaruzelska, Jadwiga, Faivre, Laurence, Wilhelm, Dagmar, Jégou, Bernard, Trainor, Paul A., Resh, Marilyn D., Antonarakis, Stylianos E., Nef, Serge“…In the present study, we report a unique case of autosomal recessive syndromic 46,XY Disorder of Sex Development (DSD) with testicular dysgenesis and chondrodysplasia resulting from a homozygous G287V missense mutation in the hedgehog acyl-transferase (HHAT) gene. This mutation occurred in the conserved membrane bound O-acyltransferase (MBOAT) domain and experimentally disrupted the ability of HHAT to palmitoylate Hh proteins such as DHH and SHH. …”
Publicado 2014
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1396por Curti, Elena, Seid, Christopher A, Hudspeth, Elissa, Center, Lori, Rezende, Wanderson, Pollet, Jeroen, Kwityn, Cliff, Hammond, Molly, Matsunami, Rise K, Engler, David A, Hotez, Peter J, Elena Bottazzi, Maria“…Previously, we reported on the expression and purification of a highly promising hookworm vaccine candidate, Na-GST-1, an N. americanus glutathione s-transferase expressed in Pichia pastoris (yeast), which led to production of 1.5 g of 95% pure recombinant protein at a 20L scale.(1)(, )(2)(, )(3) This yield and purity of Na-GST-1 was sufficient for early pilot manufacturing and initial phase 1 clinical testing. …”
Publicado 2014
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1397por Guven, Mehmet, Unal, Selin, Erhan, Duygu, Ozdemir, Nihal, Baris, Safa, Celkan, Tiraje, Bostancı, Merve, Batar, Bahadir“…Polymorphisms associated with genes coding for the glutathione S-transferase (GST) enzyme were known to affect the metabolism of different carcinogens. …”
Publicado 2015
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1398por Jiang, Xiao-Bing, Hu, Bin, He, Dong-Sheng, Mao, Zhi-Gang, Wang, Xin, Song, Bing-Bing, Zhu, Yong-Hong, Wang, Hai-Jun“…BACKGROUND: Low-level expression of O(6) methylguanine-DNA-methyl transferase (MGMT) prolactinomas has been noted previously in case reports, although what modulates MGMT expression remains unclear. …”
Publicado 2015
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1399por Song, Peipei, Inagaki, Yoshinori, Wang, Zhigang, Hasegawa, Kiyoshi, Sakamoto, Yoshihiro, Arita, Junichi, Tang, Wei, Kokudo, Norihiro“…Predictive factors associated with 1-, 3-, and 5-year survival and recurrence-free survival (RFS) were assessed using a univariate log-rank test and multivariate Cox proportional hazards regression model. Gamma-glutamyl transferase (GGT) > 100 U/L was identified as a preoperative independent risk factor affecting 1-, 3-, and 5-year survival whereas GGT > 50 U/L and indocyanine green retention 15 min (ICG-R15) > 10% were identified as preoperative independent risk factors affecting 1-, 3-, and 5-year RFS. …”
Publicado 2015
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1400por Pajaud, J, Ribault, C, Ben Mosbah, I, Rauch, C, Henderson, C, Bellaud, P, Aninat, C, Loyer, P, Morel, F, Corlu, A“…Glutathione transferases (GST) are phase II enzymes catalyzing the detoxification of endogenous noxious compounds and xenobiotics. …”
Publicado 2015
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