-
141“…The inclusion of approximately physiological amounts of human glutathione S-transferases (GSTs) A1-1, A2-2, P1-1, M1a-1a M3-3 or P1-1 (for nomenclature see Mannervik et al., 1992, Biochem. …”
Enlace del recurso
Enlace del recurso
Texto -
142“…Glutathione S-transferase (GST) isoenzyme expression is altered in a variety of neoplasms and the enzymes are implicated in metabolism of carcinogens and resistance to drugs, including cisplatin. …”
Enlace del recurso
Enlace del recurso
Texto -
143“…The presence of succinyl-coenzyme A: acetoacetate CoA--transferase (3-oxo acid-CoA transferase), an initiator of ketone body utilization in non-hepatic tissue was examined in a number of animal and human tumours of peripheral tissues. …”
Enlace del recurso
Enlace del recurso
Texto -
144
-
145por Lewis, A. D., Forrester, L. M., Hayes, J. D., Wareing, C. J., Carmichael, J., Harris, A. L., Mooghen, M., Wolf, C. R.“…An increasing body of evidence indicates that glutathione S-transferases play a role in the intrinsic and acquired resistance of tumours to anticancer drugs. …”
Publicado 1989
Enlace del recurso
Enlace del recurso
Texto -
146por Abu-Amero, Khaled K., Morales, Jose, Mohamed, Gamal H., Osman, Mazen N., Bosley, Thomas M.“…PURPOSE: Glutathione S-transferases (GSTs) are a family of enzymes that inactivate xenobiotics and endogenous end products formed as secondary metabolites during oxidative stress. …”
Publicado 2008
Enlace del recurso
Enlace del recurso
Texto -
147“…BACKGROUND: Glutathione S-transferases (GSTs) is a genetic factor for many diseases and exhibits great diversities among various populations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
148
-
149“…BACKGROUND: Oxidative stress plays a potential role in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD). Glutathione S-transferases (GSTs) detoxify toxic compounds in tobacco smoke via glutathione-dependent mechanisms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
150“…Enzyme screens with Strep-tagged recombinant proteins and expression studies with the respective green fluorescent protein (GFP) fusions have been employed to examine the functional activities and subcellular localization of members of the Arabidopsis glutathione transferase (GST) superfamily. Fifty-one of 54 GST family members were transcribed and 41 found to express as functional glutathione-dependent enzymes in Escherichia coli. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
151por Josephy, P. David“…Glutathione transferase enzymes (GSTs) catalyze reactions in which electrophiles are conjugated to the tripeptide thiol glutathione. …”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
152por Dorfmueller, Helge C., Borodkin, Vladimir S., Blair, David E., Pathak, Shalini, Navratilova, Iva, van Aalten, Daan M. F.“…In metazoa, a single, highly conserved and essential gene encodes the O-GlcNAc transferase (OGT) that transfers GlcNAc onto substrate proteins using UDP–GlcNAc as the sugar donor. …”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
153por Nair, Divya R., Ghosh, Ratna, Manocha, Alzu, Mohanty, Debasisa, Saran, Shweta, Gokhale, Rajesh S.“…Here we have identified and characterized two phosphopantetheinyl transferases from D. discoideum that exhibit distinct functional specificity. …”
Publicado 2011
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
154por Andrukhova, Olena, Salama, Mohamed, Rosenhek, Raphael, Gmeiner, Matthias, Perkmann, Thomas, Steindl, Johannes, Aharinejad, Seyedhossein“…BACKGROUND: Glutathione S-transferase P1 1 (GSTP1) belongs to the multigene isozyme family involved in cellular response to oxidative stress and apoptosis. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
155por LaCourse, E. James, Perally, Samirah, Morphew, Russell M., Moxon, Joseph V., Prescott, Mark, Dowling, David J., O'Neill, Sandra M., Kipar, Anja, Hetzel, Udo, Hoey, Elizabeth, Zafra, Rafael, Buffoni, Leandro, Pérez Arévalo, José, Brophy, Peter M.“…A new form of glutathione transferase (GST) family, Sigma class GST, closely related to a leading Schistosome vaccine candidate (Sm28), has previously been revealed by proteomics in the liver fluke but not functionally characterised. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
156por Turck, Natacha, Robin, Xavier, Walter, Nadia, Fouda, Catherine, Hainard, Alexandre, Sztajzel, Roman, Wagner, Ghislaine, Hochstrasser, Denis F., Montaner, Joan, Burkhard, Pierre R., Sanchez, Jean-CharlesEnlace del recurso
Publicado 2012
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
157por Zamaro, Paula Juliana AntoniazzoEnlace del recurso
Publicado 2012
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
158por Sanjay, Pandey, Mani, Mishra Rahasy, Sweta, Pandey, Vineet, Shah, Kumar, Ahuja Rajesh, Renu, Saxena“…BACKGROUND: Glutathione S-transferase gene deletions are known detoxification agents and cause oxidative damage. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
159por Saeed, Mohd, Baig, Mohd Hassan, Bajpai, Preeti, Srivastava, Ashwini Kumar, Ahmad, Khurshid, Mustafa, Huma“…Glutathione-S-transferase is a major phase-II detoxification enzyme in parasitic helminthes. …”
Publicado 2013
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
160por Li, Tao, Zhao, Xin-Ping, Wang, Li-Yuan, Gao, Shuai, Zhao, Jing, Fan, Yu-Chen, Wang, Kai“…Background: Glutathione-S-transferase P1 (GSTP1) is an important phase II enzyme that can protect cells from oxidative stress in various human cancers. …”
Publicado 2013
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto