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1921por Idris, Adi, Zulkipli, Ihsan N., Zulhilmi, Nurul Ramizah, Lee, Huan F., Rajabalaya, Rajan, Chee, Lim Y., Majid, Mohamed, David, Sheba R.“…Annexin-V/propidium iodide (PI) and terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL) staining was done to determine the mode of cell death. …”
Publicado 2017
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1922por Zhang, Junnan, Chen, Jiajing, Yang, Jing, Gong, Sijia, Zheng, Jiangxia, Xu, Guiyun“…By comparing different qualities oil effect on antioxidant-related genes, the expression of Glutathione S-Transferase Theta 1 (GSTT1), Glutathione S-Transferase Alpha 3 (GSTA3), Glutathione S-Transferase Omega 2 (GSTO2), and Superoxide Dismutase 2 (SOD2) were increased when dietary oils were oxidized, in which change of the GSTO2 expression was the most with 1.5% of oxidized soybean oil. …”
Publicado 2021
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1923“…In pairwise comparisons of before and during treatment timepoints, we found that those with CF-associated liver involvement experienced significant decreases in gamma-glutamyl transferase, aspartate aminotransferase-to-platelet index, and gamma-glutamyl transferase-to-platelet ratio while on lumacaftor/ivacaftor. …”
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1924“…However, only 1–3% of the total activity was recovered in the Golgi apparatus fractions under conditions where 30–50% of the UDPgalactose:N-acetylglucosamine-galactosyl transferase activity was recovered. Considering both recovery of galactosyl transferase and fraction purity, we estimate that approximately 10% of the total thiamine pyrophosphatase activity of the liver was localized within the Golgi apparatus, with a specific activity of about ten times that of the total homogenate. …”
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1925por Sharpe Elles, Lisa M., Sykes, Michael T., Williamson, James R., Uhlenbeck, Olke C.“…Escherichia coli DbpA is an ATP-dependent RNA helicase with specificity for hairpin 92 of 23S ribosomal RNA, an important part of the peptidyl transferase center. The R331A active site mutant of DbpA confers a dominant slow growth and cold sensitive phenotype when overexpressed in E. coli containing endogenous DbpA. …”
Publicado 2009
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1926“…Human DNA polymerase mu (Polμ), a family X member involved in DNA repair, has both template-directed and terminal transferase (template-independent) activities. In addition to their ability to incorporate untemplated nucleotides, another similarity between Polµ and terminal deoxynucleotidyl transferase (TdT) is their promiscuity in using ribonucleotides (NTPs), whose physiological significance is presently unknown. …”
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1927por Low, Van Lun, Chen, Chee Dhang, Lee, Han Lim, Tan, Tiong Kai, Chen, Chin Fong, Leong, Cherng Shii, Lim, Yvonne Ai Lian, Lim, Phaik Eem, Norma-Rashid, Yusoff, Sofian-Azirun, Mohd“…Nine populations demonstrated elevated levels of mixed function oxidases and glutathione-S-transferase. Acetylcholinesterase was insensitive to propoxur in all 14 populations. …”
Publicado 2013
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1928por Praskova, Eva, Plhalova, Lucie, Chromcova, Lucie, Stepanova, Stanislava, Bedanova, Iveta, Blahova, Jana, Hostovsky, Martin, Skoric, Misa, Maršálek, Petr, Voslarova, Eva, Svobodova, Zdenka“…We did not find histopathological changes and changes of selected parameters of oxidative stress (glutathione S-transferase, glutathione reductase) in tested fish. …”
Publicado 2014
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1929por Bontemps-Gallo, Sébastien, Madec, Edwige, Robbe-Masselot, Catherine, Souche, Erika, Dondeyne, Jacqueline, Lacroix, Jean-Marie“…The opgC gene encoding a transmembrane protein required for the succinylation of the OPGs in D. dadantii was found after an in silico search of a gene encoding a protein with the main characteristics recovered in the two previously characterized OpgC of E. coli and R. sphaeroides, i.e. 10 transmembrane segments and one acyl-transferase domain. Characterization of the opgC gene revealed that high osmolarity expression of the succinyl transferase is controlled by both the EnvZ-OmpR and RcsCDB phosphorelay systems. …”
Publicado 2016
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1930“…Not only we tested the functionality of the mutant transferases by expressing them and assessing their capacity to drive the appearance of A antigen on the cell surface, but we also analyzed their subcellullar localization, which has not been described before. …”
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1931por Wang, Juanjuan, Zhu, Chenggang, Song, Dan, Xia, Ruiqi, Yu, Wenbo, Dang, Yongjun, Fei, Yiyan, Yu, Long, Wu, Jiaxue“…Most small-molecule PARP inhibitors developed to date have been against PARP1, a poly-ADP-ribose transferase, and suffer from poor selectivity. PARP16, a mono-ADP-ribose transferase, has recently emerged as a potential therapeutic target, but its inhibitor development has trailed behind. …”
Publicado 2017
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1932“…Esterases, glutathione-S-transferases, and cytochrome-oxidases played less important roles in detoxification.…”
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1933por Scaiola, Alain, Leibundgut, Marc, Boehringer, Daniel, Caspers, Patrick, Bur, Daniel, Locher, Hans H., Rueedi, Georg, Ritz, Daniel“…They target the bacterial protein synthesis machinery by binding to the peptidyl transferase centre (PTC) of the ribosome and interfering with the peptidyl transferase reaction. …”
Publicado 2019
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1934por Bi, Yang, Deng, Zhiping, Ni, Weimin, Shrestha, Ruben, Savage, Dasha, Hartwig, Thomas, Patil, Sunita, Hong, Su Hyun, Zhang, Zhenzhen, Oses-Prieto, Juan A., Li, Kathy H., Quail, Peter H., Burlingame, Alma L., Xu, Shou-Ling, Wang, Zhi-Yong“…Two homologs of O-GlcNAc transferase, SECRET AGENT (SEC) and SPINDLY (SPY), which have O-GlcNAc and O-fucosyl transferase activities, respectively, are essential in Arabidopsis but have largely unknown cellular targets. …”
Publicado 2021
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1935por Adekenov, Sergazy, Zhumakayeva, Ainur, Perminov, Vladimir, Bekmanov, Bakhytzhan, Rakhimov, Kayrolla“…H-Ras may become a target for farnesyl transferase inhibitors, and in combination with other immunohistochemical factors it will contribute to the progression of a breast tumor. …”
Publicado 2020
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1936por Smith, Rebecca A., Cass, Cynthia L., Petrik, Deborah L., Padmakshan, Dharshana, Ralph, John, Sedbrook, John C., Karlen, Steven D.“…On its own, knocking out the native p‐COUMAROYL‐CoA MONOLIGNOL TRANSFERASE (BdPMT) pathway that competes for monolignols and the p‐coumaroyl‐CoA intermediate did not change ML‐FA incorporation, nor did partial loss of CINNAMOYL‐CoA REDUCTASE1 (CCR1) function, which reduced metabolic flux to monolignols. …”
Publicado 2021
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1937“…This report describes the early diagnosis of lecithin cholesterol acyl transferase deficiency in a young asymptomatic woman who initially presented to ophthalmology with bilateral corneal clouding. …”
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1938“…Recent characterizations of methyl transferases as regulators of cellular processes have spurred investigations into how methylation events might influence the HIV-1 life cycle. …”
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1939por Poli, Annarita, Nicolaus, Barbara, Chan, Kok-Gan, Kahar, Ummirul Mukminin, Chan, Chia Sing, Goh, Kian Mau“…This work also provides useful insights into glycoside hydrolases, glycoside transferases, and sugar transporters that may be involved in cellular carbohydrate metabolism.…”
Publicado 2015
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1940por Norppa, H“…For instance, erythrocytes from individuals positive for glutathione S-transferase T1 (GSTT1) express GSTT1, whereas GSTT1-null donors, having a homozygous deletion of the GSTT1 gene, completely lack this detoxification enzyme. …”
Publicado 1997
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