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801“…Group 1: early bupivacaine/tramadol, Group 2: late bupivacaine/tramadol, Group 3: early bupivacaine/dexmedetomidine, and Group 4: late bupivacaine/dexmedetomidine. …”
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802por Langford, Richard, Morte, Adelaida, Sust, Mariano, Cebrecos, Jesús, Vaqué, Anna, Ortiz, Esther, Fettiplace, James, Adeyemi, Shola, Raba, Grzegorz, But‐Husaim, Liudmila, Gascón, Neus, Plata‐Salamán, Carlos“…BACKGROUND: STARDOM2 is a randomized, double‐blind, phase 3 trial evaluating the efficacy and safety of co‐crystal of tramadol‐celecoxib (CTC)—a first‐in‐class analgesic co‐crystal comprising racemic tramadol hydrochloride and celecoxib in a supramolecular network that modifies their pharmacokinetic properties—for the management of acute postoperative pain (NCT03062644; EudraCT:2016–000593‐38). …”
Publicado 2022
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803por Costa, Giovanna L., Di Pietro, Simona, Interlandi, Claudia, Leonardi, Fabio, Macrì, Daniele, Ferrantelli, Vincenzo, Macrì, Francesco“…BACKGROUND: Tramadol produces a significant reduction in both sevoflurane and isoflurane minimum alveolar concentrations in dogs under experimental conditions. …”
Publicado 2023
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804por Tantavisut, Saran, Ho, Kok Yuen, Arandia, Edsel F, Cheng, Sze Chung, Eiamtanasate, Sarasate, Jarayabhand, Rahat, Kokseng, Raymond Alvin J, Paco, Jesse Jane L, Raju, Gopinathan, Suwanpramote, Prakrit, Thepsoparn, Marvin, Nagrale, Dinesh“…Previous clinical trials have demonstrated good results with the use of a fixed-dose combination (FDC) of tramadol 75 mg and dexketoprofen 25 mg (TRAM/DKP) in acute pain management. …”
Publicado 2023
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805“…ITS2 sequence motifs allowed an accurate in-silico distinction of the trematodes. The data indicate that ITS2 motifs (≤ 50 bp in size) can be considered promising tool for trematode species identification. …”
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806“…Patients on sufentanil had more movement-evoked pain and a higher sedation score at 4, 8, and 12 h postoperatively, as compared with the tramadol group. At 24 h, the QoR-40 was higher in the tramadol group compared with the sufentanil group. …”
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807por Kaguelidou, Florentia, Le Roux, Enora, Mangiarini, Laura, Lundin, Rebecca, de Leeuw, Thomas G, Della Pasqua, Oscar, Felisi, Mariagrazia, Bonifazi, Donato, Tibboel, Dick, Ceci, Adriana, de Wildt, Saskia N, Alberti, Corinne“…A total of 94 subjects will be randomised to receive gabapentin and tramadol placebo or tramadol and gabapentin placebo throughout 16–19 weeks (including 3 weeks of titration [optimisation period], 12 weeks of treatment at a stable dose [maintenance period] and 1–4 weeks of tapering [discontinuation period]). …”
Publicado 2019
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808“…RESULTS: The mean total tramadol consumption was significant higher in paracetamol group 250 ± 79.06 mg compared to paracetamol-diclofenac (173.81 ± 87.49 mg p = 0. 008) and paracetamol-tramadol (154.76 ± 70.54 mg p = 0. 001) group. …”
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809“…To overcome these many alternatives have been used. Tramadol has been shown to have some local anesthetic (LA) effects when used for infiltration anesthesia in dentistry. …”
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810“…Single-dose APAP exposure was similar for IR/ER HB/APAP 15/650 mg and IR tramadol HCl/APAP 75/650 mg. Steady-state hydrocodone and APAP exposures were similar between treatments. …”
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811por López-Cedrún, José, Videla, Sebastián, Burgueño, Miguel, Juárez, Inma, Aboul-Hosn, Samir, Martín-Granizo, Rafael, Grau, Joan, Puche, Miguel, Gil-Diez, José-Luis, Hueto, José-Antonio, Vaqué, Anna, Sust, Mariano, Plata-Salamán, Carlos, Monner, Antoni“…BACKGROUND: Co-crystal of tramadol–celecoxib (CTC), containing equimolar quantities of the active pharmaceutical ingredients (APIs) tramadol and celecoxib (100 mg CTC = 44 mg rac–tramadol hydrochloride and 56 mg celecoxib), is a novel API-API co-crystal for the treatment of pain. …”
Publicado 2018
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812por Duan, Guangyou, Bao, Xiaohang, Yang, Guiying, Peng, Jing, Wu, Zhuoxi, Zhao, Peng, Zuo, Zhiyi, Li, Hong“…INTRODUCTION: This study aimed to compare the postoperative analgesic effects of tramadol and hydromorphone for secondary cesarean delivery (CD) as well as their anti-anxiety and anti-depression properties. …”
Publicado 2018
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813por Harder, Achim“…As homologs of Sm.TRPM(PZQ) are also present in the other trematodes S. japonicum, S. haematobium, or Clonorchis sinensis and cestodes Taenia solium, Echinococcus multilocularis, or Hymenolepis microstoma (Park and Marchant, Trends Parasitol 36:182–194, 2020), it is suggested that a similar deadly cascade will be operating generally in PZQ-sensitive parasites.…”
Publicado 2020
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814por Elnagar, Gehad M., Elseweidy, Mohamed M., Mahmoud, Yasmin K., Elkomy, Nesreen M. I. M., Althafar, Ziyad M., Alnomasy, Sultan F., Al-Gabri, Naif A., Shawky, Mohamed“…Tramadol represents a synthetic opioid analgesic especially for mild to severe pain. …”
Publicado 2022
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816por Mamo, Mebratu, Zema, Zewde, Abera, Wogayehu, Tila, Mebratu, Darma, Bahiru, Suileman, Mohammed, Gurmu, Mesfin, Ayele, Mitiku, Demeke, Tsegaye, Sintayhu, Ashagire, Dendir, Getahun“…CONCLUSIONS: Tramadol controlled shivering early, and recurrence of shivering and incidence of sedation were also low in the tramadol group. …”
Publicado 2023
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817“…This study investigated the efficacy and tolerability of oral tapentadol and tramadol on postoperative CRBD. METHODS: This was a prospective, randomised double-blind study. 100 patients, undergoing transurethral resection of the prostate were randomly assigned into two groups to receive tramadol 100 mg (Group A) or tapentadol 50 mg (Group B) orally 1 h before surgery. …”
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818por Saleem, Muhammad Talha, Shoaib, Muhammad Harris, Yousuf, Rabia Ismail, Ahmed, Farrukh Rafiq, Ahmed, Kamran, Siddiqui, Fahad, Mahmood, Zafar Alam, Sikandar, Muhammad, Imtiaz, Muhammad Suleman“…The study is based on using SeDeM expert system in developing controlled-release tramadol HCl osmotic tablets and its in-silico physiologically based pharmacokinetic (PBPK) modeling for in-vivo pharmacokinetic evaluation. …”
Publicado 2022
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819por Kawai, Shinichi, Sobajima, Satoshi, Jinnouchi, Masashi, Nakano, Hideshi, Ohtani, Hideaki, Sakata, Mineo, Adachi, Takeshi“…BACKGROUND AND OBJECTIVES: Knee osteoarthritis pain is a chronic form of pain for which conventional non-steroidal anti-inflammatory drugs may provide insufficient analgesia. Twice-daily tramadol hydrochloride (65% sustained-release/35% immediate-release) bilayer tablets are a novel formulation of tramadol developed for managing chronic pain. …”
Publicado 2022
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820“…Two species of heterophyid trematodes were found in the Magellanic penguin, Spheniscus magellanicus (Forster), from Patagonia, Argentina. …”
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