“…We generated experimental stability data (40 confidence intervals) for two analytes—tramadol and its major metabolite (O-desmethyl-tramadol)—in two concentrations, two storage conditions, and in five sample sizes (n = 3, 4, 5, 6, or 8). …”
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“…The visual analog scale of pain, consumption of morphine and tramadol for pain relief in 48 hours, and side effects were recorded. …”
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“…There were no differences in doses of paracetamol and tramadol, or in adverse effects.…”
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“…Herein, we present our experience of management of such cases with a single epidural injection of local anaesthetic, tramadol and methylprednisolone, and table tilt for management of both radiculopathies. …”
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“…MBP and HR increased significantly due to pneumoperitoneum at T3, T4 and T5, compared with T1 and T2 within Group N, and were higher at T3, T4 and T5 in Group N than at the same time points in Group O. Tramadol consumption was statistically lower in Group O (P=0.0003). …”
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“…Rescue analgesia was provided with IM tramadol (2 mg kg(−1)), and the pain scores were reassessed 30 min after the rescue intervention. …”
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“…Twenty-four hours after surgery, the mean tramadol consumption was (55.45 ± 30.51) versus (37.27 ± 27.09) mg in TAP and II-IH groups, respectively (p = 0.009). …”
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“…RESULTS: The prescription of opioids became significantly more common while the use of tramadol decreased significantly. The staff reported that 63.4% in 2007 and 62.3% in 2013 had experienced pain. …”
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“…Cholestasis was induced by bile duct resection in mice and physical dependence was induced by administration of morphine and/or tramadol three times daily (8, 12 and 16 h) at the doses of 25, 50 and 75 mg/kg during three consecutive days. …”
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“…On day 5–8, treatment continued with Gabapentin and Tramadol injections, and the pain scale (NRS) decreased to 2–3. …”
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“…However, lornoxicam + paracetamol and tramadol + paracetamol were effective because of their sustained releasing ability. …”
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“…It can block voltage-dependent sodium and potassium channels, cause serotonin release, and inhibit norepinephrine reuptake and can also be used as an adjuvant in PNBs. However, tramadol’s effectiveness and safety as an adjuvant to local anesthetic for PNB are inconsistent. …”
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“…CONCLUSION: High preoperative anxiety increased the immediate postoperative pain score and 24 h tramadol consumption. It would be better to decrease preoperative anxiety levels to reduce postoperative pain and 24 h analgesic consumption.…”
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“…Studies showed that tramadol is also an effective drug used to control shivering in most patients, and its effect is comparable with the pethidine.…”
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“…Morphine, codeine, 6-acetylmorphine, nalbuphine, tramadol and dextromethorphan were selected as target opioids. …”
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“…Within 24 h after surgery, the requirements for tramadol in Group A (0.25 g) and Group B (0.35 g) were significantly lower than those in Group C (0.75 g) (p < 0.05). …”
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“…The primary outcomes included the VAS score and dose of tramadol from the first to the third day after surgery. …”
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“…Forty two patients received meperidine and 49 received tramadol. Rigors were tabulated using the proxy of number of doses of as needed (PRN) rigor medications and normalized by IL2 doses. …”
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“…In hot plate test, after 30 min of administration, our test compound showed significant anti-nociceptive potential (p < 0.05 at 15 and 30 mg kg(−1) and p < 0.01 at 45 mg kg(−1)) and tramadol (p ˂ 0.001) at 30 mg kg(−1) dose. After 60 min tramadol (30 kg(−1)) and test sample (30, 45 mg kg(−1)) exhibited significant anti-nociceptive activity p < 0.001. …”
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“…In conclusion, opioids and psychotropic medications dominated by morphine, tramadol and quetiapine most frequently caused medication‐related deaths in PNUIDs. …”
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