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41por Sarbu, Laura G., Shova, Sergiu, Peptanariu, Dragos, Sandu, Isabela A., Birsa, Lucian M., Bahrin, Lucian G.“…In this paper, we present the cytotoxic effects of five tricyclic flavonoids, one of which was previously identified as a potent antimicrobial agent. …”
Publicado 2019
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42por Mohammed, Anber F., Andrei, Graciela, Hayallah, Alaa M., Abdel-Moty, Samia G., Snoeck, Robert, Simons, Claire“…A series of tricyclic penciclovir (PCV) and hydroxybutylguanine (HBG) derivatives have been prepared with enhanced lipophilicity following an efficient synthetic route. …”
Publicado 2019
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43por Samaan, George N., Wyllie, Mckenzie K., Cizmic, Julian M., Needham, Lisa-Maria, Nobis, David, Ngo, Katrina, Andersen, Susan, Magennis, Steven W., Lee, Steven F., Purse, Byron W.“…Aiming to improve on these properties, we designed a new tricyclic pyrimidine nucleoside analogue with a push–pull conjugated system and synthesized it in seven sequential steps. …”
Publicado 2020
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44por Nguyen, Hiep, Kidron, Ariel, Ghildyal, Christopher, Veluri, Shriya, Nguyen, Nghi, Nguyen, Quan, Nguyen, Hoang“…Tricyclic antidepressant (TCA) is a known frequently used and highly potent antidepressant that serves as an unsuspecting source of acute human poisoning. …”
Publicado 2021
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45por Asensi-Cantó, Antonio, López-Abellán, María Dolores, Castillo-Guardiola, Verónica, Hurtado, Ana María, Martínez-Penella, Mónica, Luengo-Gil, Ginés, Conesa-Zamora, Pablo“…SIMPLE SUMMARY: Tricyclic antidepressants (TCAs) are old and known therapeutic agents whose good safety profile makes them good candidates for drug repurposing. …”
Publicado 2022
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46por Abd Rani, Nur Zahirah, Lee, Yean Kee, Ahmad, Sarfraz, Meesala, Ramu, Abdullah, Iskandar“…A marine natural product possesses a diverse and unique scaffold that contributes to a vast array of bioactivities. Tricyclic guanidine alkaloids are a type of scaffold found only in marine natural products. …”
Publicado 2022
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47“…The synthesis of new iodine containing synthetic tricyclic flavonoids is reported. Due to the sensitivity of the precursors to the heat and acidic conditions required for the ring closure of the 1,3-dithiolium core, a new cyclization method has been developed. …”
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49por Würschum, Tobias, Liu, Wenxin, Busemeyer, Lucas, Tucker, Matthew R, Reif, Jochen C, Weissmann, Elmar A, Hahn, Volker, Ruckelshausen, Arno, Maurer, Hans PeterEnlace del recurso
Publicado 2014
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52por Robin, Valérie, Griffith, Graziella, Carter, John-Paul L., Leumann, Christian J., Garcia, Luis, Goyenvalle, Aurélie“…In this study, we show that systemic delivery of tricyclo-DNA (tcDNA) AONs in a type III SMA mouse augments retention of exon 7 in SMN2 mRNA both in peripheral organs and the CNS. …”
Publicado 2017
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53por Relizani, Karima, Echevarría, Lucía, Zarrouki, Faouzi, Gastaldi, Cécile, Dambrune, Chloe, Aupy, Philippine, Haeberli, Adrian, Komisarski, Marek, Tensorer, Thomas, Larcher, Thibaut, Svinartchouk, Fedor, Vaillend, Cyrille, Garcia, Luis, Goyenvalle, Aurélie“…Tricyclo-DNA (tcDNA) is a conformationally constrained oligonucleotide analog that has demonstrated great therapeutic potential as antisense oligonucleotide (ASO) for several diseases. …”
Publicado 2021
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56por Niculescu-Duvaz, Dan, Niculescu-Duvaz, Ion, Suijkerbuijk, Bart M.J.M., Ménard, Delphine, Zambon, Alfonso, Nourry, Arnaud, Davies, Lawrence, Manne, Helen A., Friedlos, Frank, Ogilvie, Lesley, Hedley, Douglas, Takle, Andrew K., Wilson, David M., Pons, Jean-Francois, Coulter, Tom, Kirk, Ruth, Cantarino, Neus, Whittaker, Steven, Marais, Richard, Springer, Caroline J.Enlace del recurso
Publicado 2010
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57“…BACKGROUND: Several studies suggest links between cancer and tricyclic antidepressant use. METHODS: A case–control study using the General Practice Research Database examined whether previous tricyclic usage was associated with reduced incidence of brain (with glioma as a sub-category), breast, colorectal, lung and prostate cancers. …”
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58por Wietecha-Posłuszny, Renata, Garbacik, Aneta, Woźniakiewicz, Michał, Kościelniak, Paweł“…The objective of this research was to develop, optimize, and validate a modern, rapid method of preparation of human hair samples, using microwave irradiation, for analysis of eight tricyclic antidepressants (TCADs): nordoxepin, nortriptyline, imipramine, amitriptyline, doxepin, desipramine, clomipramine, and norclomipramine. …”
Publicado 2010
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59“…The resultants were reacted with acetic anhydride to afford the benzoxazinone intermediates, which upon condensation with elected amines in either DMF or ethanol gave the corresponding tricyclic 4(3H)-quinazolinone derivatives. It was found that reactions in DMF produced higher yields.…”
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