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121por Li, Yuqing, Ma, Yeying, Xia, Yinzheng, Zhang, Tao, Sun, Shuaishuai, Gao, Jiangtao, Yao, Hongwei, Wang, Huan“…Herein, we report the discovery and biosynthesis of bacteria-derived tricyclic lanthipeptide noursin, which is constrained by a tri amino acid labionin crosslink and an unprecedented histidine-to-butyrine crosslink, named histidinobutyrine. …”
Publicado 2023
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122por Sarker, Subhodeep, Weissensteiner, René, Steiner, Ilka, Sitte, Harald H, Ecker, Gerhard F, Freissmuth, Michael, Sucic, SonjaEnlace del recurso
Publicado 2010
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123“…The kinetics of the oxidation of two tricyclic antidepressants (TCA) namely, imipramine (IMP) and clomipramine (CLM) with sodium N-chloro-p-toluenesulfonamide or chloramine-T (CAT) in HClO(4) medium was studied at 300 K. …”
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124“…We aimed in our study to clarify the influence of selected tricyclic antidepressants (TCAs) on mast cell function: secretion, uptake, and reuptake of 5-HT, that could interfere with 5-HT levels and in this way contribute to the generation of pain. …”
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125por Timoshenko, Mariya A., Kharitonov, Yurii V., Shakirov, Makhmut M., Bagryanskaya, Irina Yu., Shults, Elvira E.“…A selective synthesis of 7‐ or 14‐nitrogen containing tricyclic diterpenoids was completed according to a strategy in which the key step was the catalyzed direct allylic amination of methyl 14α‐hydroxy‐15,16‐dihydroisopimarate with a wide variety of nitrogenated nucleophiles. …”
Publicado 2015
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126por Zhao, Wenting, Pang, Qin, Xu, Ruixue, Liu, Jianwen, Liu, Shengfa, Li, Jian, Su, Xin-zhuanEnlace del recurso
Publicado 2016
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127por Wang, Xiaojing, Barbosa, James, Blomgren, Peter, Bremer, Meire C., Chen, Jacob, Crawford, James J., Deng, Wei, Dong, Liming, Eigenbrot, Charles, Gallion, Steve, Hau, Jonathon, Hu, Huiyong, Johnson, Adam R., Katewa, Arna, Kropf, Jeffrey E., Lee, Seung H., Liu, Lichuan, Lubach, Joseph W., Macaluso, Jen, Maciejewski, Pat, Mitchell, Scott A., Ortwine, Daniel F., DiPaolo, Julie, Reif, Karin, Scheerens, Heleen, Schmitt, Aaron, Wong, Harvey, Xiong, Jin-Ming, Xu, Jianjun, Zhao, Zhongdong, Zhou, Fusheng, Currie, Kevin S., Young, Wendy B.“…[Image: see text] In our continued effort to discover and develop best-in-class Bruton’s tyrosine kinase (Btk) inhibitors for the treatment of B-cell lymphomas, rheumatoid arthritis, and systemic lupus erythematosus, we devised a series of novel tricyclic compounds that improved upon the druglike properties of our previous chemical matter. …”
Publicado 2017
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128por Iqbal, Jamshed, El-Gamal, Mohammed I., Ejaz, Syeda Abida, Lecka, Joanna, Sévigny, Jean, Oh, Chang-Hyun“…Herein, a series of tricyclic coumarin sulphonate 1a-za with known antiproliferative activity, was evaluated for AP inhibition against human tissue nonspecific alkaline phosphatase (h-TNAP) and human intestinal alkaline phosphatase (h-IAP). …”
Publicado 2018
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129por Zhang, Xin, Liu, Qiang, Li, Qianqian, Li, Yinghong, Liu, Zhandong, Deng, Hongbin, Tang, Sheng, Wang, Yanxiang, Wang, Youchun, Song, Danqing“…Twenty-six novel tricyclic sophoridinic and matrinic derivatives containing a common chlorinated benzene fragment were designed, synthesized and evaluated for their anti-ebolavirus (EBOV) activities. …”
Publicado 2018
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130“…Next, the intramolecular CuAAC of the linear precursor successfully produced the well-defined tricyclic triblock terpolymer with narrow dispersity in a reasonable yield. …”
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131por Abuelizz, Hatem A., Iwana, Nor Azman N. I., Ahmad, Rohaya, Anouar, El-Hassane, Marzouk, Mohamed, Al-Salahi, Rashad“…We have synthesized 25 tricyclic 2-phenoxypyrido[3,2-e][1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-ones hybrids and evaluated their α-glucosidase inhibitory activity. …”
Publicado 2019
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132por Geiselman, Gina M., Kirby, James, Landera, Alexander, Otoupal, Peter, Papa, Gabriella, Barcelos, Carolina, Sundstrom, Eric R., Das, Lalitendu, Magurudeniya, Harsha D., Wehrs, Maren, Rodriguez, Alberto, Simmons, Blake A., Magnuson, Jon K., Mukhopadhyay, Aindrila, Lee, Taek Soon, George, Anthe, Gladden, John M.“…RESULTS: We developed a biomass deconstruction and conversion process that enabled the production of two tricyclic sesquiterpenes, epi-isozizaene and prespatane, from the woody biomass poplar using the versatile basidiomycete Rhodosporidium toruloides. …”
Publicado 2020
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133por Cho, Hyewon, Lee, Eun, Kwon, Hye Ah, Seul, Lee, Jeon, Hui-Jeon, Yu, Ji Hoon, Ryu, Jae-Ha, Jeon, RaokEnlace del recurso
Publicado 2020
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134por Vos, Cornelis F., Aarnoutse, Rob E., Op de Coul, Marijke J. M., Spijker, Jan, Groothedde-Kuyvenhoven, Mascha M., Mihaescu, Raluca, Wessels-Basten, Sonja J. W., Rovers, Jordy J. E., ter Hark, Sophie E., Schene, Aart H., Hulscher, Marlies E. J. L., Janzing, Joost G. E.“…BACKGROUND: Traditionally tricyclic antidepressants (TCAs) have an important place in treatment of major depressive disorder (MDD). …”
Publicado 2021
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135por Rio, Irina S. R., Rodrigues, Ana Rita O., Rodrigues, Juliana M., Queiroz, Maria-João R. P., Calhelha, R. C., Ferreira, Isabel C. F. R., Almeida, Bernardo G., Pires, Ana, Pereira, André M., Araújo, João P., Castanheira, Elisabete M. S., Coutinho, Paulo J. G.“…Two new potential antitumor fluorescent drugs, tricyclic lactones derivatives of thienopyridine, were loaded in these nanosystems with very high encapsulation efficiencies (higher than 98%). …”
Publicado 2021
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136por Koike, Rima, Watanabe, Yoshihiro, Kato, Kazuho, Mikasa, Yudai, Shimizu, Kota, Nonaka, Kenichi, Honsho, Masako, Suga, Takuya, Hokari, Rei, Ishiyama, Aki, Asami, Yukihiro, Iwatsuki, Masato“…Four new tricyclic macrolides, named shikinefragalides A (1), B (2), C (3) and D (4), were isolated by physicochemical (PC) screening from a static culture material of Stachybotryaceae sp. …”
Publicado 2022
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137por Ruf, Sven, Rajagopal, Sridharan, Kadnur, Sanjay Venkatachalapathi, Hallur, Mahanandeesha S., Rani, Shilpa, Kristam, Rajendra, Swaminathan, Srinivasan, Zope, Bharat Ravindra, Gondrala, Pavan Kumar, Swamy, Indu, Putta, V. P. Rama Kishore, Kandan, Saravanan, Zech, Gernot, Schreuder, Herman, Rudolph, Christine, Elvert, Ralf, Czech, Joerg, Birudukota, Swarnakumari, Siddiqui, M. Amir, Anand, Niranjan Naranapura, Mane, Vishal Subhash, Dittakavi, Sreekanth, Suresh, Juluri, Gosu, Ramachandraiah, Ramesh, Mullangi, Yura, Takeshi, Dhakshinamoorthy, Saravanakumar, Kannt, Aimo“…We conducted a high-throughput screening campaign that led to the identification of a tricyclic core as a potential NNMT small molecule inhibitor series. …”
Publicado 2022
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139por Bizot, Flavien, Fayssoil, Abdallah, Gastaldi, Cécile, Irawan, Tabitha, Phongsavanh, Xaysongkhame, Mansart, Arnaud, Tensorer, Thomas, Brisebard, Elise, Garcia, Luis, Juliano, Rudolph L, Goyenvalle, AurélieEnlace del recurso
Publicado 2023
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