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Mostrando 161 - 180 Resultados de 2,273 Para Buscar 'Tricicle~', tiempo de consulta: 3.05s Limitar resultados
  1. 161
    “…Background. Poisoning with tricyclic antidepressants (TCAs) is still a major concern for emergency physicians and intensivists. …”
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    Arterial Blood Gas Analysis and the Outcome of Treatment in Tricyclic Antidepressants Poisoned Patients with Benzodiazepine Coingestion
  2. 162
    “…A tricyclic lactam is reported in a four step synthesis sequence via Beckmann rearrangement and ring-rearrangement metathesis as key steps. …”
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    Synthesis of a tricyclic lactam via Beckmann rearrangement and ring-rearrangement metathesis as key steps
  3. 163
    “…To assess their potential toxicity, we have determined their cytotoxicity against rat myoblast L6 cells and their AChE inhibitory activity. Several tricyclic heterofused quinoline derivatives were found to display an interesting multi-trypanosomatid profile, with one-digit micromolar potencies against two of these parasites and two-digit micromolar potency against the other. …”
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    Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity
  4. 164
    “…Starting from γ-ketoesters with an o-iodobenzyl group we studied a palladium-catalyzed cyclization process that stereoselectively led to bi- and tricyclic compounds in moderate to excellent yields. …”
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    Stereoselective synthesis of tricyclic compounds by intramolecular palladium-catalyzed addition of aryl iodides to carbonyl groups
  5. 165
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    A Counterion‐Directed Approach to the Diels–Alder Paradigm: Cascade Synthesis of Tricyclic Fused Cyclopropanes
  6. 166
    “…Poisoning with tricyclic antidepressants is an important cause of drug-related self-poisoning in the developed world and a very common cause of poisoning and mortality in developing countries. …”
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    Cardiotoxicity of tricyclic antidepressant treated by 2650 mEq sodium bicarbonate: A case report
  7. 167
    “…We screened 1600 compounds and identified 21 small molecules that induce HSC inactivation. Four hits were tricyclic antidepressants (TCAs), and they repressed expression of pro-fibrotic factors Alpha-Actin-2 (ACTA2) and Alpha-1 Type I Collagen (COL1A1) in HSCs. …”
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    Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells
  8. 168
    “…Tricyclic furan derivatives with multiple chiral centers are ubiquitous in natural products. …”
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    Two-step synthesis of chiral fused tricyclic scaffolds from phenols via desymmetrization on nickel
  9. 169
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    Synthesis and biological evaluation of tricyclic matrinic derivatives as a class of novel anti-HCV agents
  10. 170
    por Giwa, Al, Oey, Edwin
    Publicado 2018
    “…Tricyclic antidepressants (TCAs) were first approved by the Food and Drug Administration (FDA) for use as antidepressants in the 1950s. …”
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    The return of an old nemesis: Survival after severe tricyclic antidepressant toxicity, a case report
  11. 171
    “…Amitriptyline, a tricyclic antidepressant, is commonly used to treat depression and neuropathic pain, but its mechanism is still unclear. …”
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    Tricyclic antidepressant amitriptyline inhibits 5-hydroxytryptamine 3 receptor currents in NCB-20 cells
  12. 172
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    Electrochemical Characterization of Central Action Tricyclic Drugs by Voltammetric Techniques and Density Functional Theory Calculations
  13. 173
    “…INTRODUCTION: The relationship between benzodiazepines, opioids and tricyclic antidepressants and trauma is of great importance because of increased consumption and the growing evidence of a positive association among older adults. …”
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    Association of benzodiazepines, opioids and tricyclic antidepressants use and falls in trauma patients: Conditional effect of age
  14. 174
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    Tricyclic Nucleobase Analogs and Their Ribosides as Substrates and Inhibitors of Purine-Nucleoside Phosphorylases III. Aminopurine Derivatives
  15. 175
    por Fei, Teng, Du, Yao, He, Chunlin, Pang, Siping
    Publicado 2018
    “…In addition, our design strategy, which combines the azoxy moiety and fused tricyclic skeleton to construct nitrogen-rich molecular structures with high density and positive heat of formation, is a valuable approach for developing novel high-energy-density materials with excellent performance and stability.…”
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    Theoretical investigations on azole-fused tricyclic 1,2,3,4-tetrazine-2-oxides
  16. 176
    “…A set of substituted non‐canonical tricyclic cyclobutanes were synthesized under mild conditions using [(Ph(3)P)(2)Fe(CO)(NO)]BF(4) as catalyst in good to excellent yields with high levels of stereocontrol.…”
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    Iron‐Catalyzed Cycloisomerization and C−C Bond Activation to Access Non‐canonical Tricyclic Cyclobutanes
  17. 177
    “…A novel nitrated [6,6,6]tricycles-derived compound containing nitro, methoxy, and ispropyloxy groups, namely SK1, was developed in our previous report. …”
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    Antioral Cancer Effects by the Nitrated [6,6,6]Tricycles Compound (SK1) In Vitro
  18. 178
    “…To identify such a novel class of antibiotics, a chemical library of unique 3-D bioinspired molecules was explored revealing a promising, mycobacterium specific Tricyclic SpiroLactam (TriSLa) hit. Chemical optimization of the TriSLa scaffold delivered potent analogues with nanomolar activity against replicating and nonreplicating Mycobacterium tuberculosis. …”
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    Tricyclic SpiroLactams Kill Mycobacteria In Vitro and In Vivo by Inhibiting Type II NADH Dehydrogenases
  19. 179
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    A case against the trickle-down effect in technology ecosystems
  20. 180
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    Nitric Oxide Trickle Drives Heme into Hemoglobin and Muscle Myoglobin
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