Mostrando 121 - 140 Resultados de 2,369 Para Buscar 'Verkami~', tiempo de consulta: 1.39s Limitar resultados
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    por Yao, Xiaoming, Verkman, Alan S.
    Publicado 2017
    “…We reported evidence previously, using CD59(−/−) mice, that the membrane-associated complement inhibitor CD59 modulates CDC in NMO (Zhang and Verkman, J. Autoimmun. 53:67–77, 2014). Motivated by the observation that rats, unlike mice, have human-like complement activity, here we generated CD59(−/−) rats to investigate the role of CD59 in NMO and to create NMO pathology by passive transfer of AQP4-IgG under conditions in which minimal pathology is produced in normal rats. …”
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  7. 127
    por Yao, Xiaoming, Verkman, Alan S.
    Publicado 2017
    “…We recently reported that rats lacking complement inhibitor protein CD59 were highly susceptible to development of NMO pathology in brain and spinal cord following direct AQP4-IgG administration (Yao and Verkman, Acta Neuropath Commun 2017, 5:15). Here, we report evidence that CD59 is responsible for protection of peripheral, AQP4-expressing tissues in seropositive NMO. …”
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