Synthesis and Biological Evaluation of Phosphate Prodrugs of 4-Phospho-d -erythronohydroxamic Acid, an Inhibitor of 6-Phosphogluconate Dehydrogenase

por Ruda, Gian Filippo, Alibu, Vincent P, Mitsos, Christos, Bidet, Olivier, Kaiser, Marcel, Brun, Reto, Barrett, Michael P, Gilbert, Ian H
Publicado 2007

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

por Dennehy, Kevin M, Ferwerda, Gerben, Faro-Trindade, Inês, Pyż, Elwira, Willment, Janet A, Taylor, Philip R, Kerrigan, Ann, Tsoni, S Vicky, Gordon, Siamon, Meyer-Wentrup, Friederike, Adema, Gosse J, Kullberg, Bart-Jan, Schweighoffer, Edina, Tybulewicz, Victor, Mora-Montes, Hector M, Gow, Neil A R, Williams, David L, Netea, Mihai G, Brown, Gordon D
Publicado 2008

Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases

por Brenk, Ruth, Schipani, Alessandro, James, Daniel, Krasowski, Agata, Gilbert, Ian Hugh, Frearson, Julie, Wyatt, Paul Graham
Publicado 2008

Synthesis of Natural-Product-Like Molecules with Over Eighty Distinct Scaffolds**

por Morton, Daniel, Leach, Stuart, Cordier, Christopher, Warriner, Stuart, Nelson, Adam
Publicado 2008

β-Selection: Abundance of TCRβ(–)/γδ(–) CD44(–)CD25(–) (DN4) cells in the foetal thymus

por Hager-Theodorides, Ariadne L, Rowbotham, Nicola J, Outram, Susan V, Dessens, Johannes T, Crompton, Tessa
Publicado 2007

Investigation of Distribution of Heavy Metals between Blood Plasma and Blood Cells

por Tautkus, Stasys, Irnius, Algimantas, Speiciene, Danute, Barkauskas, Jurgis, Kareiva, Aivaras
Publicado 2007

Pannexin-1-dependent caspase-1 activation and secretion of IL-1β is regulated by zinc

por Brough, David, Pelegrin, Pablo, Rothwell, Nancy J
Publicado 2009

A Novel Mycolactone Toxin Obtained by Biosynthetic Engineering

por Hong, Hui, Stinear, Tim, Porter, Jessica, Demangel, Caroline, Leadlay, Peter F
Publicado 2007

Synthesis, Conformation, and Activity of Human Insulin-Like Peptide 5 (INSL5)

por Hossain, Mohammed Akhter, Bathgate, Ross A D, Kong, Chze K, Shabanpoor, Fazel, Zhang, Suode, Haugaard-Jönsson, Linda M, Rosengren, K Johan, Tregear, Geoffrey W, Wade, John D
Publicado 2008

Functional and biophysical characterization of an HLA-A*6801-restricted HIV-specific T cell receptor

por Gostick, Emma, Cole, David K, Hutchinson, Sarah L, Wooldridge, Linda, Tafuro, Sabrina, Laugel, Bruno, Lissina, Anna, Oxenius, Annette, Boulter, Jonathan M, Price, David A, Sewell, Andrew K
Publicado 2007

A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection

por Barr, Daniel P, Belz, Gabrielle T, Reading, Patrick C, Wojtasiak, Magdalena, Whitney, Paul G, Heath, William R, Carbone, Francis R, Brooks, Andrew G
Publicado 2007

Emerging trends in plasma‐free manufacturing of recombinant protein therapeutics expressed in mammalian cells

por Grillberger, Leopold, Kreil, Thomas R., Nasr, Sonia, Reiter, Manfred
Publicado 2009

The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells

por Mahajan, Simmi, Cervera, Ana, MacLeod, Megan, Fillatreau, Simon, Perona-Wright, Georgia, Meek, Stephen, Smith, Andrew, MacDonald, Andrew, Gray, David
Publicado 2007

Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy

por Kropf, Pascale, Baud, David, Marshall, Sara E, Munder, Markus, Mosley, Angelina, Fuentes, José M, Bangham, Charles R M, Taylor, Graham P, Herath, Shanti, Choi, Beak-San, Soler, Germán, Teoh, Tg, Modolell, Manuel, Müller, Ingrid
Publicado 2007

TLR-mediated stimulation of APC: Distinct cytokine responses of B cells and dendritic cells

por Barr, Tom A, Brown, Sheila, Ryan, Gemma, Zhao, Jiexin, Gray, David
Publicado 2007

Characterisation of the expression and function of the GM-CSF receptor α-chain in mice

por Rosas, Marcela, Gordon, Siamon, Taylor, Philip R
Publicado 2007

Adenosine closes the K(+) channel K(Ca)3.1 in human lung mast cells and inhibits their migration via the adenosine A(2A) receptor

por Duffy, S Mark, Cruse, Glenn, Brightling, Christopher E, Bradding, Peter
Publicado 2007

Peptide-based immunotherapy of experimental autoimmune encephalomyelitis without anaphylaxis

por Leech, Melanie D, Chung, Chen-Yen, Culshaw, Abigail, Anderton, Stephen M
Publicado 2007

DC activated via dectin-1 convert Treg into IL-17 producers

por Osorio, Fabiola, LeibundGut-Landmann, Salomé, Lochner, Matthias, Lahl, Katharina, Sparwasser, Tim, Eberl, Gérard, Reis e Sousa, Caetano
Publicado 2008

CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions

por Laugel, Bruno, Price, David A, Milicic, Anita, Sewell, Andrew K
Publicado 2007