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24701
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24702por Meyers-Needham, Marisa, Ponnusamy, Suriyan, Gencer, Salih, Jiang, Wenhui, Thomas, Raquela J, Senkal, Can E, Ogretmen, Besim“…Here we report that the CerS1 promoter was repressed by HDAC1-dependent inhibition of Sp1 recruitment to two specific GC-boxes spanning the −177 and −139 region. Moreover, an alternatively spliced variant CerS1 mRNA (CerS1-2) was detected mainly in cancer cells or primary tumour tissues compared to controls, which was targeted by miR-574-5p for degradation. …”
Publicado 2012
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24703por Koltsida, Ourania, Hausding, Michael, Stavropoulos, Athanasios, Koch, Sonja, Tzelepis, George, Übel, Caroline, Kotenko, Sergei V, Sideras, Paschalis, Lehr, Hans A, Tepe, Marcus, Klucher, Kevin M, Doyle, Sean E, Neurath, Markus F, Finotto, Susetta, Andreakos, Evangelos“…Recently, IL-28 cytokine family members were found to be profoundly down-regulated in allergic asthma. We now reveal a novel role of IL-28 cytokines in inducing type 1 immunity and protection from allergic airway disease. …”
Publicado 2011
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24704por Dietz, U. A., Wichelmann, C., Wunder, C., Kauczok, J., Spor, L., Strauß, A., Wildenauer, R., Jurowich, C., Germer, C. T.Enlace del recurso
Publicado 2012
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24705
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24706“…Our hypothesis was that in patients with a high risk of infection Rituximab (RTX) could be a safer alternative. METHODS: We analyzed the outcome of RA patients who received RTX instead of TNF-alpha antagonist because of a history of serious infections or frequent infectious events. …”
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24707“…RESULTS: Treatment of THP-1 cells with various concentration of HDM extract induced marked up- regulation of the expression of cytokines IL-10 and IL-6, which indicated that allergic responses were efficiently induced. Recombinant CCL3L1 protein had no effect on cytokine expression of THP-1 Cells in absence of HDM extract stimulation. …”
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24708por Cingi, Cemal, Oghan, Fatih, Eskiizmir, Gorkem, Yaz, Aytekin, Ural, Ahmet, Erdogmus, Nagehan“…OBJECTIVE: To determine prognostic value of acoustic rhinometry in patients with perennial allergic rhinitis (PAR) treated with montelukast in fix combination with desloratidine and to assess effectiveness of this medication on health-related quality of life (HRQL). …”
Publicado 2012
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24709“…BACKGROUND: Hypoxia-inducible factor 1 is a transcription complex that plays a pivotal role in cellular adaptation to low oxygen availability, which occurs during allergic responses, host immune defence and leukaemia progression. …”
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24710“…BACKGROUND: We examined rates of comorbid allergy-related respiratory conditions among patients diagnosed with allergic rhinitis (AR) to characterize AR-related disease burden. …”
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24711
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24712por Wilm, Andreas, Aw, Pauline Poh Kim, Bertrand, Denis, Yeo, Grace Hui Ting, Ong, Swee Hoe, Wong, Chang Hua, Khor, Chiea Chuen, Petric, Rosemary, Hibberd, Martin Lloyd, Nagarajan, NiranjanEnlace del recurso
Publicado 2012
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24713por Szalai, Krisztina, Kopp, Tamara, Lukschal, Anna, Stremnitzer, Caroline, Wallmann, Julia, Starkl, Philipp, Vander Elst, Luc, Saint-Remy, Jean-Marie, Pali-Schöll, Isabella, Jensen-Jarolim, Erika“…The presented mouse model is suitable for investigating the mechanisms of allergic eczema.…”
Publicado 2012
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24714
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24715“…Background. Allergic asthma is showed an increase in Th2-cytokine and IgE levels and an accumulation activation of Th2 cells, eosinophils and mast cells. …”
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24716por Hassan, Musa A, Melo, Mariane B, Haas, Brian, Jensen, Kirk D C, Saeij, Jeroen P J“…BACKGROUND: Accurate gene model predictions and annotation of alternative splicing events are imperative for genomic studies in organisms that contain genes with multiple exons. …”
Publicado 2012
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24717por Combs, Stephanie E, Ganswindt, Ute, Foote, Robert L, Kondziolka, Douglas, Tonn, Jörg-ChristianEnlace del recurso
Publicado 2012
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24718“…It appears that Maca-GO may act as a toner of hormonal processes, leading to alleviation of discomfort felt by perimenopausal women, hence, its potential use as non-hormonal alternative to HRT program.…”
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24719por Curigliano, Giuseppe, Criscitiello, Carmen, Andrè, Fabrice, Colleoni, Marco, Di Leo, Angelo“…The recognition that early breast cancer is a spectrum of diseases each requiring a specific systemic therapy guided the 13th St Gallen International Breast Cancer Consensus Conference [1]. …”
Publicado 2013
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24720