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  1. 25901
    Publicado 1996
    “…To obtain a "humanized" animal model that responds to human IgE in allergic reactions, transgenic mice expressing the human Fc epsilon RI alpha chain were generated. …”
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    Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor alpha chain respond to human IgE in mast cell degranulation and in allergic reactions
  2. 25902
    “…We have previously found that in Ca(V)1.4 L-type Ca(2+) channels, activation, voltage, and calcium-dependent inactivation are controlled by an intrinsic distal C-terminal modulator. Because alternative splicing in the Ca(V)1.3 α1 subunit C terminus gives rise to a long (Ca(V)1.3(42)) and a short form (Ca(V)1.3(42A)), we investigated if a C-terminal modulatory mechanism also controls Ca(V)1.3 gating. …”
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    Modulation of Voltage- and Ca(2+)-dependent Gating of Ca(V)1.3 L-type Calcium Channels by Alternative Splicing of a C-terminal Regulatory Domain
  3. 25903
    “…This model was then used to assess the possibility of alternative or cryptic splicing within the highly variable immune response gene family known as 185/333. …”
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    A method for identifying alternative or cryptic donor splice sites within gene and mRNA sequences. Comparisons among sequences from vertebrates, echinoderms and other groups
  4. 25904
    “…Importantly, we identified a human alternatively spliced BK channel variant, hSloΔ(579–664), in which these trafficking signals are excluded because of in-frame exon skipping. …”
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    Membrane Trafficking of Large Conductance Calcium-activated Potassium Channels Is Regulated by Alternative Splicing of a Transplantable, Acidic Trafficking Motif in the RCK1-RCK2 Linker
  5. 25905
    “…The side chain of F122, facing a secondary hydrophobic pocket (Pocket 2), interacts with the Alix peptide. An alternatively spliced shorter isoform, designated ALG-2(ΔGF122), lacks Gly(121)Phe(122 )and does not bind Alix, but the structural basis of the incompetence has remained to be elucidated. …”
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    Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2(ΔGF122)) and structural roles of F122 in target recognition
  6. 25906
    “…These data clearly indicate that SIVsmm relies on CCR5-independent entry pathways in SM that are homozygous for defective CCR5 alleles and, while the extent of alternative coreceptor use in SM with CCR5 wild type alleles is uncertain, strongly suggest that SIVsmm tropism and host cell targeting in vivo is defined by the distribution and use of alternative entry pathways in addition to CCR5. …”
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    A Novel CCR5 Mutation Common in Sooty Mangabeys Reveals SIVsmm Infection of CCR5-Null Natural Hosts and Efficient Alternative Coreceptor Use In Vivo
  7. 25907
    “…A well-trained medical assistant could be considered an alternative for assigning major causes of neonatal deaths in rural Bangladesh and in similar settings where physicians are scarce and their time costs more. …”
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    A comparison of physicians and medical assistants in interpreting verbal autopsy interviews for allocating cause of neonatal death in Matlab, Bangladesh: can medical assistants be considered an alternative to physicians?
  8. 25908
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    The Tennessee Children's Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases
  9. 25909
    por Patel, Ami, Tikoo, Suresh, Kobinger, Gary
    Publicado 2010
    “…Overall, PAV3-based vector is capable of mediating swift, strong immune responses and offer a promising alternative to AdHu5.…”
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    A Porcine Adenovirus with Low Human Seroprevalence Is a Promising Alternative Vaccine Vector to Human Adenovirus 5 in an H5N1 Virus Disease Model
  10. 25910
    “…IgE binding to these proteins was studied in sera from 59 latex-allergic patients and 20 banana-allergic patients without latex allergy by ELISA and ELISA inhibition. …”
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    Latex-allergic patients sensitized to the major allergen hevein and hevein-like domains of class I chitinases show no increased frequency of latex-associated plant food allergy
  11. 25911
    “…These results suggest that decreased sFlt-1 expression due to hypoxia contributes to hypoxia-induced angiogenesis and reveals a novel mechanism regulating angiogenesis by alternative mRNA 3′-end processing.…”
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    Hypoxia down-regulates sFlt-1 (sVEGFR-1) expression in human microvascular endothelial cells by a mechanism involving mRNA alternative processing
  12. 25912
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    Online Artículo Texto
    Ambient Particulate Matter Induces Interleukin-8 Expression through an Alternative NF-κB (Nuclear Factor-Kappa B) Mechanism in Human Airway Epithelial Cells
  13. 25913
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    Online Artículo Texto
    Use of Omalizumab to treat a nine-year old, with steroid-dependent, allergic asthma, adrenal insufficiency and vertebral compression fractures due to steroid induced severe osteoporosis
  14. 25914
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    Online Artículo Texto
    Chimeric superficial temporal artery based skin and temporal fascia flap plus temporalis muscle flap – An alternative to free flap for suprastructure maxillectomy with external skin defect
  15. 25915
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    Online Artículo Texto
    Variable Regions of PI4P 5-Kinases Direct PtdIns(4,5)P(2) Toward Alternative Regulatory Functions in Tobacco Pollen Tubes
  16. 25916
    “…The c-Myb gene encodes the p75(c-Myb) isoform and less-abundant proteins generated by alternatively spliced transcripts. Among these, the best known is p(c-Mybex9b), which contains 121 additional amino acids between exon 9 and 10, in a domain involved in protein–protein interactions and negative regulation. …”
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    Expression of p89(c-Mybex9b), an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells
  17. 25917
    “…BACKGROUND: Previous studies show an increased interest and usage of complementary and alternative medicine (CAM) in the general population and among health care workers both internationally and nationally. …”
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    Knowledge about complementary, alternative and integrative medicine (CAM) among registered health care providers in Swedish surgical care: a national survey among university hospitals
  18. 25918
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    Online Artículo Texto
    Can Alberta infant motor scale and milani comparetti motor development screening test be rapid alternatives to bayley scales of infant development-II at high-risk infants
  19. 25919
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    Online Artículo Texto
    Bone marrow-derived, alternatively activated macrophages enhance solid tumor growth and lung metastasis of mammary carcinoma cells in a Balb/C mouse orthotopic model
  20. 25920
    “…The varied functional requirements satisfied by trans fatty acid (TFA)—containing oils constrains the selection of alternative fats and oils for use as potential replacements in specific food applications. …”
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    Predicted Changes in Fatty Acid Intakes, Plasma Lipids, and Cardiovascular Disease Risk Following Replacement of trans Fatty Acid-Containing Soybean Oil with Application-Appropriate Alternatives
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