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25921
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25922por Ohno, Genta, Ono, Kanako, Togo, Marina, Watanabe, Yohei, Ono, Shoichiro, Hagiwara, Masatoshi, Kuroyanagi, Hidehito“…However, mechanisms orchestrating the processing of the entire transcript are not well understood. Muscle-specific alternative pre–mRNA processing of the unc-60 gene in Caenorhabditis elegans, encoding two tissue-specific isoforms of ADF/cofilin with distinct biochemical properties in regulating actin organization, provides an excellent in vivo model of complex and tissue-specific pre–mRNA processing; it consists of a single first exon and two separate series of downstream exons. …”
Publicado 2012
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25923por Chavez Villarreal, Karen Giselle, Hernandez, Jahzeel Avila, Goytia Acevedo, Raquel Concepción, Velazquez, Rocio Meza, Guillen, Mario Rivera, Jurado, Michelle Gomez, García-Arenas, Guadalupe, Maravilla-Domínguez, Aurora“…BACKGROUND: There are precedents to suggest that lead exposure may increase the severity of allergic disease in children. In Torreon Coahuila is known the problem of lead contamination and its association with the body burden in children. …”
Publicado 2012
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25924por Khateb, Samer, Zelinger, Lina, Ben-Yosef, Tamar, Merin, Saul, Crystal-Shalit, Ornit, Gross, Menachem, Banin, Eyal, Sharon, Dror“…A subsequent WES analysis of the two index cases revealed a shared homozygous novel nucleotide deletion (c.1220delG) leading to a frameshift (p.Gly407Glufs*56) in an alternative exon (#15) of USH1C. Screening of additional Yemenite Jewish patients revealed a total of 16 homozygous RP patients (with a carrier frequency of 0.008 in controls). …”
Publicado 2012
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25925por Steel, Amie, Adams, Jon, Sibbritt, David, Broom, Alex, Gallois, Cindy, Frawley, Jane“…BACKGROUND: There is little known about women’s concurrent use of conventional and complementary health care during pregnancy, particularly consultation patterns with complementary and alternative medicine (CAM). This study examines health service utilisation among pregnant women including consultations with obstetricians, midwives, general practitioners (GPs) and CAM practitioners. …”
Publicado 2012
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25926por Fanning, Laura B., Buckley, Carolyn C., Xing, Wei, Breslow, Rebecca G., Katz, Howard R.“…Our data establish a new mechanism by which LILRB4 can downregulate the development of pathologic allergic inflammation: reduced upregulation of key molecules needed for DC migration leading to decreases in Th2 cells in lymph nodes and their target tissue.…”
Publicado 2013
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25927“…RESULTS: We have developed a novel protein structure alignment algorithm, MICAN (a structure alignment algorithm that can handle Multiple-chain complexes, Inverse direction of secondary structures, C(α) only models, Alternative alignments, and Non-sequential alignments). …”
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25928por Higginson, I, Rumble, C, Koffman, J, Hopkins, P, Heenen, S, Prentice, W, Burman, R, Leonard, S, Dampier, O, Noble, J, Morgan, M, Shipman, CEnlace del recurso
Publicado 2013
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25929por Kargi, Aysegul, Bisgin, Atil, Yalcin, Arzu Didem, Kargi, Bulent, Sahin, Emel, Gumuslu, SaadetEnlace del recurso
Publicado 2013
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25930por Goodman, Richard, Gupta, Ashok, Mahesh, Padukudru A, Singh, Anand B, Komarla, Nagendra, Van Ree, Ronald, Mills, EN Clare, Taylor, Steve LEnlace del recurso
Publicado 2013
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25931
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25932por Quah, Phaik Ling, Huang, Chiung-Hui, Shi Shek, Lynette,Pei, Aw, Marion, Lee, Bee Wah, Kuo, I-ChunEnlace del recurso
Publicado 2013
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25933por de la Cueva, Ana, Ramírez de Molina, Ana, Álvarez-Ayerza, Néstor, Ramos, Ma Angeles, Cebrián, Arancha, del Pulgar, Teresa Gómez, Lacal, Juan Carlos“…The effect of ChoKα inhibitors in combination with 5-FU as a new alternative for the treatment of colon tumors has been investigated both in vitro in CRC-tumour derived cell lines, and in vivo in mouse xenografts models. …”
Publicado 2013
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25934por Murphy, Kevin, Gawchik, Sandra, Bernstein, David, Andersen, Jens, Pedersen, Martin Rud“…We evaluated grass allergy immunotherapy tablet (AIT) treatment in North American adults with grass pollen-induced allergic rhinitis with or without conjunctivitis (AR/C), with/without asthma. …”
Publicado 2013
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25935“…We add to this discussion by quantifying how many years behind comparison countries the USA has fallen and by identifying when US mortality rates began to diverge. …”
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25936
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25937por Georgescu, I, Gavriliu, S, Pârvan, A, Martiniuc, A, Japie, E, Ghiță, R, Drăghici, I, Hamei, S, Ţiripa, I, El Nayef, T, Dan, DEnlace del recurso
Publicado 2013
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25938
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25939por Fritz, Zoë, Malyon, Alexandra, Frankau, Jude M., Parker, Richard A., Cohn, Simon, Laroche, Clare M., Palmer, Chris R., Fuld, Jonathan P.“…AIMS: To determine whether the introduction of the Universal Form of Treatment Options (the UFTO), as an alternative approach to Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) orders, reduces harms in patients in whom a decision not to attempt cardiopulmonary resuscitation (CPR) was made, and to understand the mechanism for any observed change. …”
Publicado 2013
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25940por Ojeda, Pedro, Piqué, Núria, Alonso, Alicia, Delgado, Julio, Feo, Francisco, Igea, Juan Manuel, Navarro, Ana, Olaguibel, José María, Subiza, Javier, Nieto, Carles, Andersson, Morgan“…BACKGROUND: Since barrier protection measures to avoid contact with allergens are being increasingly developed, we assessed the clinical efficacy and tolerability of a topical nasal microemulsion made of glycerol esters in patients with allergic rhinitis. METHODS: Randomized, controlled, double-blind, parallel group, multicentre, multinational clinical trial in which adult patients with allergic rhinitis or rhinoconjunctivitis due to sensitization to birch, grass or olive tree pollens received treatment with topical microemulsion or placebo during the pollen seasons. …”
Publicado 2013
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