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27561por Kajita, Kimihiro, Goshima, Satoshi, Noda, Yoshifumi, Kawada, Hiroshi, Kawai, Nobuyuki, Okuaki, Tomoyuki, Honda, Masatoshi, Matsuo, MasayukiEnlace del recurso
Publicado 2018
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27562por Barrio-Galán, Rubén Del, Úbeda, Cristina, Gil, Mariona, Medel-Marabolí, Marcela, Sieczkowski, Nathalie, Peña-Neira, ÁlvaroEnlace del recurso
Publicado 2019
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27563por Schmitz, S.I., Widholz, B., Essers, C., Becker, M., Tulyaganov, D.U., Moghaddam, A., Gonzalo de Juan, I., Westhauser, F.“…However, under certain circumstances BGs such as the well-known 45S5 Bioglass® (composition in wt%: 45.0 SiO(2), 24.5 Na(2)O, 24.5 CaO, 6.0 P(2)O(5)) act cytotoxic due to a strong increase in pH caused by a burst release of sodium ions. A potential alternative is a sodium-reduced fluoride-containing BG belonging to the CaO–MgO–SiO(2) system, namely BG1d-BG (composition in wt%: 46.1 SiO(2), 28.7 CaO, 8.8 MgO, 6.2 P(2)O(5), 5.7 CaF(2), 4.5 Na(2)O), that has already been evaluated in-vitro, in-vivo and in preliminary clinical trials. …”
Publicado 2020
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27564por Fang, Shu-Bin, Zhang, Hong-Yu, Wang, Cong, He, Bi-Xin, Liu, Xiao-Qing, Meng, Xiang-Ci, Peng, Ya-Qi, Xu, Zhi-Bin, Fan, Xing-Liang, Wu, Zhang-Jin, Chen, Dong, Zheng, Lei, Zheng, Song Guo, Fu, Qing-Ling“…Group 2 innate lymphoid cells (ILC2s) are recently reported to play a more critical role in allergic diseases. We previously identified that mesenchymal stromal cells (MSCs) elicited therapeutic effects on allergic airway inflammation. …”
Publicado 2020
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27565por Miller, Bradley Scott, Rihs, Silvia, Parween, Shaheena, Ternand, Christine, Gregory, Louise Cheryl, Dattani, Mehul Tulsidas, Pandey, Amit V“…Computational prediction of transcription indicated that alternative splicing is likely to produce a shorter GH variant with skipping of exon 3 in GH1. …”
Publicado 2020
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27566por Theobald, NigelEnlace del recurso
Publicado 2020
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27567por Sim, Hyejin, Lee, Tae-Kyeong, Yoo, Yeon Ho, Ahn, Ji Hyeon, Kim, Dae Won, Kim, Bora, Lee, Jae-Chul, Park, Joon Ha, Lim, Soon-Sung, Park, Jung-Seok, Kang, Il Jun, Kim, Young-Myeong, Shin, Myoung Cheol, Cho, Jun Hwi, Park, Yoonsoo, Won, Moo-HoEnlace del recurso
Publicado 2021
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27568“…The present study aimed to investigate the correlation of long non-coding RNA nuclear-enriched abundant transcript 1 (lncRNA NEAT1) with microRNA (miR)-21, miR-124, and miR-125a, and their associations with disease risk, severity, and inflammatory cytokines of allergic rhinitis (AR). Totally 70 AR patients and 70 non-atopic obstructive snoring patients (as controls) were recruited. …”
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27569“…The objective of this study was to evaluate the prognostic value of tumor size effects on prognosis in T3a RCC and propose an alternative tumor stage system combined with T1‐2. METHODS: Data relating to T1‐3aN0M0 RCC (n = 49586) were obtained from the Surveillance, Epidemiology, and End Results database (2004–2015). …”
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27570por Shinjyo, Noriko, Hikosaka, Kenji, Kido, Yasutoshi, Yoshida, Hiroki, Norose, Kazumi“…In addition to the core components C3 and C1q, anaphylatoxin C3a and C5a receptors (C3aR and C5aR1), as well as alternative complement pathway components properdin (CFP) and factor B (CFB), were significantly upregulated 2 weeks after inoculation. …”
Publicado 2021
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27571por Sprague, Sheila, Bhandari, Mohit, Bzovsky, Sofia, Scott, Taryn, Thabane, Lehana, Heels-Ansdell, Diane, O’Toole, Robert V., Howe, Andrea, Gaski, Greg E., Hill, Lauren C., Brown, Krista M., Viskontas, Darius, Zomar, Mauri, Della Rocca, Gregory J., Slobogean, Gerard P.“…OBJECTIVES: To conduct a pilot trial for the Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH-2) protocol to assess feasibility of a definitive trial. …”
Publicado 2020
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27572por Okumura, Norihito, Soh, Junichi, Suzuki, Hiroyuki, Nakata, Masao, Fujiwara, Toshiya, Nakamura, Hiroshige, Sonobe, Makoto, Fujinaga, Takuji, Kataoka, Kazuhiko, Gemba, Kenichi, Kataoka, Masafumi, Hotta, Katsuyuki, Yoshioka, Hiroshige, Matsuo, Keitaro, Sakamoto, Junichi, Date, Hiroshi, Toyooka, Shinichi“…BACKGROUND: The aim of this multicenter, randomized phase II study was to analyze the feasibility and safety of alternate-day S-1, an oral fluoropyrimidine, for adjuvant chemotherapy in patients with completely resected pathological stage I (tumor diameter > 2 cm) non-small cell lung cancer (NSCLC). …”
Publicado 2021
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27573por Piao, Yihua, Jiang, Jingzhi, Wang, Zhiguang, Wang, Chongyang, Jin, Shan, Li, Li, Li, Liangchang, Piao, Hongmei, Jin, Zhehu, Zhu, Lianhua, Yan, Guanghai“…Consequently, these data suggest that GLA regulates the NrF2/HO-1 signaling pathway through p38MAPK phosphorylation and inhibits HMGB1/TLR4/NF-κB signaling pathway to reduce mast cell degranulation and allergic inflammation. Our findings could be used as a promising therapeutic drug against allergic inflammatory disease.…”
Publicado 2021
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27574“…The main purpose of this study was to investigate whether the blockade of the interaction between the receptor activator of nuclear factor-κB (NF-ĸB) ligand (RANKL) and its receptor RANK as well as the blockade of NF-κB inhibitor kinase (IKK) and of NF-κB translocation have the potential to suppress the pathogenesis of allergic asthma by inhibition and/or enhancement of the production by CD4(+) and CD8(+) T cells of important cytokines promoting (i.e., IL-4 and IL-17) and/or inhibiting (i.e., IL-10 and TGF-β), respectively, the development of allergic asthma. …”
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27576por Shah, Manish A., Udrea, Anghel Adrian, Bondarenko, Igor, Mansoor, Was, Sánchez, Raquel Guardeño, Sarosiek, Tomasz, Bozzarelli, Silvia, Schenker, Michael, Gomez-Martin, Carlos, Morgan, Carys, Özgüroğlu, Mustafa, Pikiel, Joanna, Kalofonos, Haralabos P., Wojcik, Elzbieta, Buchler, Tomas, Swinson, Daniel, Cicin, Irfan, Joseph, Mano, Vynnychenko, Ihor, Luft, Alexander Valerievich, Enzinger, Peter C., Salek, Tomas, Papandreou, Christos, Tournigand, Christophe, Maiello, Evaristo, Wei, Ran, Ferry, David, Gao, Ling, Oliveira, Joana M., Ajani, Jaffer A.“…ABSTRACT: Studies JVDB and JVCZ examined alternative ramucirumab dosing regimens as monotherapy or combined with paclitaxel, respectively, in patients with advanced/metastatic gastric/gastroesophageal junction (GEJ) adenocarcinoma. …”
Publicado 2022
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27577por Zhang, Yong, Fang, Yuan, Ma, Lijie, Xu, Jing, Lv, Chentao, Deng, Li, Zhu, Guanghui“…Moreover, LINC00857 was confirmed to recruit serine/arginine-rich splicing factor 1 (SRSF1) to promote the alternative splicing (AS) targeting CLDN12, affecting the phenotypes of PAAD cells. …”
Publicado 2022
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27579por Zharskaia, Nina A., Solomatina, Anastasia I., Liao, Yu-Chan, Galenko, Ekaterina E., Khlebnikov, Alexander F., Chou, Pi-Tai, Chelushkin, Pavel S., Tunik, Sergey P.“…The key result of this study consists of the demonstration of an alternative approach for the preparation of NIR biosensors by taking advantage of in situ generation of NIR emission due to the nanoconfined aggregation of Pt (II) complexes inside the micellar nanocarriers.…”
Publicado 2022
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27580por Kasapoglu, Muhammed Zahid, Sagdic, Osman, Avci, Esra, Tekin-Cakmak, Zeynep Hazal, Karasu, Salih, Turker, Rabia Sena“…This study aimed to investigate the potential use of cold-pressed coconut oil by-products (COB) as a low-cost alternative source for plant-based drink and ice cream production. …”
Publicado 2023
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