“…The resulting data violates assumptions of variant callers developed for bulk sequencing. Thus, only dedicated models accounting for amplification bias and errors can provide accurate calls. …”
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“…First, the balance of 133 elderly individuals, including 32 fallers, was measured on a relatively inexpensive, portable force platform (Wii Balance Board, Nintendo) with a 25‐s open‐eyes protocol. …”
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“…Step Test, turn sway, depression, physical activity level and edge contrast sensitivity were significantly worse for fallers (p < 0.05). Multiple logistic regression analysis showed that turning performance, visual acuity and back pain were significantly associated with falls risk, accounting for 72% of the variance of risk factors for falls among studied population. …”
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“…Frequent fallers were only seen among those with slower walk (T10max > 10seconds), and fewer steps in the STEP test (STEP≤5 steps). …”
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“…Women represented 59% of callers. Most calls were from those aged 41–50 and 71–80 years old. …”
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“…METHOD: A nation-wide helpline, Lifeline Aoteroa, provided data from distressed callers obtained from May 2017 to April 2018. The analyzed sample consisted of 32,889 counseling calls of clients with a wide range of presenting issues. …”
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“…We evaluate Variabel on both synthetic data (SARS-CoV-2) and patient derived datasets (Ebola virus, norovirus, SARS-CoV-2); our results show that Variabel can accurately identify low frequency variants below 0.5 allele frequency, outperforming existing state-of-the-art ONT variant callers for this task. Variabel is open-source and available for download at: www.gitlab.com/treangenlab/variabel.…”
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“…We benchmarked SavvyCNV against five state-of-the-art CNV callers using truth sets generated from genome sequencing data and Multiplex Ligation-dependent Probe Amplification assays. …”
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“…BACKGROUND: In several African and Asian countries, callers to mobile phones sometimes hear a song or message in place of the typical ringing sound. …”
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“…We present a tool, Minos, which combines outputs from arbitrary variant callers, increasing recall without loss of precision. …”
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“…The inhibition of bitter taste signalling components with gallein (G(βγ) subunits), U73122 (phospholipase C), 2-APB (IP3-receptors) or with TPPO (Trpm5, transient receptor potential-melastatin 5 channel) reduced the denatonium effect. …”
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“…This study aimed to establish a clinical physical and functional profile of the patients with neuromusculoskeletal and cognitive disorders and fallers in interventions within SGRS. From a retrospective study design, 127 medical records were compiled and analyzed to determine the physical and functional profile of older adults and differences according to sex, age groups and the benefits for local physical therapy intervention. …”
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“…We established a high-confidence SV callset with 8938 SVs by integrating four alignment-based SV callers, including 109× Pacific Biosciences (PacBio) continuous long reads (CLRs), 22× PacBio circular consensus sequencing (CCS) reads, 104× Oxford Nanopore Technologies (ONT) long reads, and 114× Bionano optical mapping platform, and one de novo assembly-based SV caller using CCS reads. …”
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“…A Manchester screening decision tree was adopted, to define a set of guidelines to provide support to the callers, based mainly on the guidelines defined by the Order of Portuguese Psychologists. …”
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“…Approximately equal numbers of callers were advised active management of administering rabies PEP and conservative management of withholding PEP. …”
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“…We fitted a mixed logistic regression model with random intercepts for county and state and identified associations between caller type and the following: animal characteristics (i.e., age, weight, breed-class), type of toxicant, season, year, and access to veterinary services (i.e., veterinarians per capita in the county of the caller). …”
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“…Prior studies have displayed differences in postural dynamics and stability in older adults with a fall history (FH) and those who are non-fallers (NF), suggesting surplus alterations that occur in some older adults (i.e., FH group) in addition to the natural aging process. …”
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“…We demonstrate SCExecute with two popular variant callers—GATK and Strelka2—executed in shell-scripts together with commands for BAM file manipulation and variant filtering, to detect single-cell-specific expressed single nucleotide variants from droplet scRNA-seq data (10X Genomics Chromium System). …”
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“…The second line of defense would be to develop original protocols to detect future fallers before any fall occur. This paper briefly summarizes the current advancements and perspectives that may arise from the combination of affordable and easy-to-use non-wearable systems (force platforms, 3D tracking motion systems), wearable systems (accelerometers, gyroscopes, inertial measurement units-IMUs) with appropriate machine learning analytics, as well as the efforts to address these challenges.…”
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