“…In the present case, we showed that a lesion with genetic alterations based on the histological sequence SSA/P → high-grade SSA/P → cancer in SSA/P and an alternative serrated pathway may exhibit aggressive behavior.…”
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“…In this review, we discuss recent work leading to better utilization of alternative substrates. This review aims to provide a comprehensive understanding of the current state of knowledge for alternative substrate utilization, suggest potential pathways identified through homology in the absence of prior characterization, discuss recent work that either identifies, endogenous or cryptic metabolism, and describe metabolic engineering to improve alternative substrate utilization. …”
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“…BACKGROUND: There is currently considerable uncertainty regarding what the predictors of the severity of diagnostic or accidental food allergic reactions are, and to what extent the severity of such reactions can be predicted. …”
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“…Local allergic rhinitis (LAR) in patients with no systemic markers of atopy is a very interesting phenomenon due to the lack of any definitive explanation for the mechanism of this IgE-dependent reaction. …”
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“…Switching between TSH receptor stimulating antibodies (TSAb) and TSH receptor blocking antibodies (TBAb) most likely accounts for presentations of alternating hyperthyroidism and hypothyroidism. To achieve stability of thyroid function, definitive therapy is recommended to remove the pathological thyroid.…”
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“…Alternative splicing (AS) is a fundamental regulatory process in all higher eukaryotes. …”
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“…The most severe allergic reaction in the patient’s life occurred after eating a mango fruit. …”
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“…Studying the pathophysiology of allergic fungal rhinosinusitis (AFRS) has proved challenging. …”
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“…This commentary outlines a protein engineering approach as an alternative to immobilisation developed in our laboratory. …”
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“…Alternative splicing may result in the partial or complete skipping of exons, or the partial inclusion of introns, as documented at the transcription level. …”
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“…Allergic rhinitis (AR) is a critical public health, medical and economic problem in China. …”
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“…Although several studies have suggested increased risks of atopic dermatitis, allergic rhinitis, and allergic sensitization in relation to PM exposure, the evidence remains inconsistent. …”
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“…The prevalence of allergic disorders has been increasing worldwide and significantly impacts the quality of life of the atopic individual. …”
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“…Alternative splicing and transcription elongation by RNA polymerase II (RNAPII) are two processes which are tightly connected. …”
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