A ROCK inhibitor suppresses the transforming growth factor-beta-2-induced endothelial–mesenchymal transition in Schlemm’s canal endothelial cells

por Fujimoto, Tomokazu, Inoue-Mochita, Miyuki, Inoue, Toshihiro
Publicado 2023

Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells

por Diep, Duy Trong Vien, Hong, Kyungki, Khun, Triyeng, Zheng, Mei, ul-Haq, Asad, Jun, Hee-Sook, Kim, Young-Bum, Chun, Kwang-Hoon
Publicado 2018

ROCK 1 and 2 affect the spatial architecture of 3D spheroids derived from human corneal stromal fibroblasts in different manners

por Ida, Yosuke, Umetsu, Araya, Furuhashi, Masato, Watanabe, Megumi, Tsugeno, Yuri, Suzuki, Soma, Hikage, Fumihito, Ohguro, Hiroshi
Publicado 2022

RhoA/Rock activation represents a new mechanism for inactivating Wnt/β-catenin signaling in the aging-associated bone loss

por Shi, Wei, Xu, Chengyun, Gong, Ying, Wang, Jirong, Ren, Qianlei, Yan, Ziyi, Mei, Liu, Tang, Chao, Ji, Xing, Hu, Xinhua, Qv, Meiyu, Hussain, Musaddique, Zeng, Ling-Hui, Wu, Ximei
Publicado 2021

Circ_0057558 promotes nonalcoholic fatty liver disease by regulating ROCK1/AMPK signaling through targeting miR-206

por Chen, Xi, Tan, Qing-Qing, Tan, Xin-Rui, Li, Shi-Jun, Zhang, Xing-Xing
Publicado 2021

Fumigaclavine C ameliorates liver steatosis by attenuating hepatic de novo lipogenesis via modulation of the RhoA/ROCK signaling pathway

por Yu, Wanguo, Gao, Yaxin, Zhao, Zaoya, Long, Xiufeng, Yi, Yi, Ai, Shuo
Publicado 2023

Long non-coding RNA CCHE1 participates in postoperative distant recurrence but not local recurrence of osteosarcoma possibly by interacting with ROCK1

por Zhang, Zhi, Yu, Tao, Geng, Wei
Publicado 2020

Conditional deletion of ROCK2 induces anxiety-like behaviors and alters dendritic spine density and morphology on CA1 pyramidal neurons

por Weber, Audrey J., Adamson, Ashley B., Greathouse, Kelsey M., Andrade, Julia P., Freeman, Cameron D., Seo, Jung Vin, Rae, Rosaria J., Walker, Courtney K., Herskowitz, Jeremy H.
Publicado 2021

NMMHC IIA Inhibition Ameliorates Cerebral Ischemic/Reperfusion-Induced Neuronal Apoptosis Through Caspase-3/ROCK1/MLC Pathway

por Wang, Guang-Yun, Wang, Tie-Zheng, Zhang, Yuan-Yuan, Li, Fang, Yu, Bo-Yang, Kou, Jun-Ping
Publicado 2020

Hypoxic induction of vasculogenic mimicry in hepatocellular carcinoma: role of HIF-1 α, RhoA/ROCK and Rac1/PAK signaling

por Zhang, Ji-Gang, Zhou, He-Ming, Zhang, Xue, Mu, Wan, Hu, Juan-Ni, Liu, Gao-Lin, Li, Qin
Publicado 2020

“What’s happening in Syria even affects the rocks”: a qualitative study of the Syrian refugee experience accessing noncommunicable disease services in Jordan

por McNatt, Zahirah Zahrah, Freels, Patricia Elaine, Chandler, Hannah, Fawad, Muhammad, Qarmout, Sandy, Al-Oraibi, Amani Saleh, Boothby, Neil
Publicado 2019

∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling

por Campbell, Hamish, Fleming, Nicholas, Roth, Imogen, Mehta, Sunali, Wiles, Anna, Williams, Gail, Vennin, Claire, Arsic, Nikola, Parkin, Ashleigh, Pajic, Marina, Munro, Fran, McNoe, Les, Black, Michael, McCall, John, Slatter, Tania L., Timpson, Paul, Reddel, Roger, Roux, Pierre, Print, Cristin, Baird, Margaret A., Braithwaite, Antony W.
Publicado 2018

Osteosarcoma cell intrinsic PD-L2 signals promote invasion and metastasis via the RhoA-ROCK-LIMK2 and autophagy pathways

por Ren, Tingting, Zheng, Bingxin, Huang, Yi, Wang, Shidong, Bao, Xing, Liu, Kuisheng, Guo, Wei
Publicado 2019

ROCK inhibition with Fasudil induces beta-catenin nuclear translocation and inhibits cell migration of MDA-MB 231 human breast cancer cells

por Guerra, Fabiana Sélos, Oliveira, Ramon Guerra de, Fraga, Carlos Alberto Manssour, Mermelstein, Claudia dos Santos, Fernandes, Patricia Dias
Publicado 2017

Experimental characterization of [Formula: see text] /water multiphase flow in heterogeneous sandstone rock at the core scale relevant for underground hydrogen storage (UHS)

por Boon, Maartje, Hajibeygi, Hadi
Publicado 2022

Enhanced terrestrial Fe(II) mobilization identified through a novel mechanism of microbially driven cave formation in Fe(III)-rich rocks

por Parker, Ceth W., Senko, John M., Auler, Augusto S., Sasowsky, Ira D., Schulz, Frederik, Woyke, Tanja, Barton, Hazel A.
Publicado 2022

Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles

por Shan, Shidong, Su, Min, Li, Yan, Wang, Zhen, Liu, Daoquan, Zhou, Yongying, Fu, Xun, Yang, Shu, Zhang, Junchao, Qiu, Jizhang, Liu, Huan, Zeng, Guang, Chen, Ping, Wang, Xinghuan, DiSanto, Michael E., Guo, Yuming, Zhang, Xinhua
Publicado 2023

Boron isotope record of peak metamorphic ultrahigh-pressure and retrograde fluid–rock interaction in white mica (Lago di Cignana, Western Alps)

por Halama, Ralf, Konrad-Schmolke, Matthias, De Hoog, Jan C. M.
Publicado 2020

LncRNA NEAT1 Acts as an miR-148b-3p Sponge to Regulate ROCK1 Inhibition of Retinoblastoma Growth

por Lu, Hang, Zhang, Zhenjun, Lu, Yao, Xiu, Weiwei, Cui, Jinglin
Publicado 2021

A gravimetric assessment of the Gotthard Base Tunnel geological model: insights from a novel gravity terrain-adaptation correction and rock physics data

por Scarponi, M., Hetényi, G., Baron, L., Marti, U.
Publicado 2022